Na H Exchange


Na H Exchange
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The Sodium Hydrogen Exchanger


The Sodium Hydrogen Exchanger
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Author : Morris Karmazyn
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Sodium Hydrogen Exchanger written by Morris Karmazyn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


I am extremely honored and pleased to have the opportunity to write a few introductory words for this timely volume on Na + /It exchange. This is a field of investigation that I entered into by challenge and necessity, embraced with passion and fmally left in my quest for new discoveries in growth control. Ten years, one third of my scientific life, has been devoted to uncovering the mysteries of intracellular pH (PH;) regulation with respect to growth factor action. I got started on this new topic in 1980, when I heard a rather provocative hypothesis presented by Enrique Rozengurt at an ICN-UCLA Keystone meeting on "Cell Surface and Malignancy". He showed that all mitogens induced amiloride-sensitive Na + entry into resting cells and proposed that, if a compound stimulates Na + influx, it could be a mitogen. In support of his proposal Enrique reported that the amphipathic polypeptide, mellitin, which induced Na+ influx, was indeed mitogenic for 3T3 cells. This was only correlation at this stage. However, I was fascinated by this talk. I immediately approached Enrique to inform him of my skepticism about this beautiful story, and to indicate that I would only be convinced when I succeeded in isolating mutant fibroblasts lacking the amiloride-sensitive Na+ transporter. ''Good luck!" was his response.



The Na H Exchanger


The Na H Exchanger
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Author : Larry Fliegel
language : en
Publisher: New York : Springer
Release Date : 1996

The Na H Exchanger written by Larry Fliegel and has been published by New York : Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.




Na H Exchange


Na H Exchange
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Author : S. Grinstein
language : en
Publisher: CRC Press
Release Date : 2018-05-04

Na H Exchange written by S. Grinstein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-04 with Science categories.


Prepared by leading scientists in the field, these volumes compile for the first time, concise, up-to-date reviews of several aspects of the basic properties, distribution, function and regulation of the Na+/H+ antiport. In addition, current methods and the use of inhibitors and ligands for the study of the exchanger are described. These volumes are indispendable to researchers and students in the areas of ion transport, membrane biology and cellular physiology.



Na H Antiporter


Na H Antiporter
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Author : Marc Alan Post
language : en
Publisher:
Release Date : 1992

Na H Antiporter written by Marc Alan Post and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.




Experimental Neurochemistry


Experimental Neurochemistry
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Author : Abel Lajtha
language : en
Publisher: Springer
Release Date : 1982-12-01

Experimental Neurochemistry written by Abel Lajtha and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-12-01 with Science categories.


The second volume of the Handbook does not parallel any volume of the first edition; it is one more sign, or reflection, of the expansion of the field. By emphasizing the experimental approach, it illustrates the tools that have re cently become available for investigating the nervous system. Also, perhaps even more than other volumes, it illustrates the multidisciplinary nature of the field, requiring multidisciplinary methodology. It is now recognized that the availability of methodology is often the rate-limiting determinant of studies and that improvements or innovations in instrumentation can open up new avenues. A new improved method, although opening up new possibilities and being crucial to making advances, is only a tool whose use will determine its use fulness. If we do not recognize its possibilities, its use will be limited; if we do not recognize its limitations, it will mislead us. It is the possibilities and limitations and the results obtained that are illustrated here.



The Alkali Metal Ions Their Role For Life


The Alkali Metal Ions Their Role For Life
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Author : Astrid Sigel
language : en
Publisher: Springer
Release Date : 2016-02-09

The Alkali Metal Ions Their Role For Life written by Astrid Sigel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-09 with Science categories.


MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.



The Na H Exchanger In Blood Brain Barrier Endothelial Cells


The Na H Exchanger In Blood Brain Barrier Endothelial Cells
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Author : Tina Iun San Lam
language : en
Publisher:
Release Date : 2009

The Na H Exchanger In Blood Brain Barrier Endothelial Cells written by Tina Iun San Lam and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.




Savage Exchange


Savage Exchange
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Author : Tamara T. Chin
language : en
Publisher: BRILL
Release Date : 2020-10-26

Savage Exchange written by Tamara T. Chin and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-26 with History categories.


Savage Exchange explores the politics of representation during the Han dynasty (206 BCE–220 CE) at a pivotal moment when China was asserting imperialist power on the Eurasian continent and expanding its local and long-distance (“Silk Road”) markets. Tamara T. Chin explains why rival political groups introduced new literary forms with which to represent these expanded markets. To promote a radically quantitative approach to the market, some thinkers developed innovative forms of fiction and genre. In opposition, traditionalists reasserted the authority of classical texts and advocated a return to the historical, ethics-centered, marriage-based, agricultural economy that these texts described. The discussion of frontiers and markets thus became part of a larger debate over the relationship between the world and the written word. These Han debates helped to shape the ways in which we now define and appreciate early Chinese literature and produced the foundational texts of Chinese economic thought. Each chapter in the book examines a key genre or symbolic practice (philosophy, fu-rhapsody, historiography, money, kinship) through which different groups sought to reshape the political economy. By juxtaposing well-known texts with recently excavated literary and visual materials, Chin elaborates a new literary and cultural approach to Chinese economic thought. Co-Winner, 2016 Harry Levin Prize, American Comparative Literature Association; Honorable Mention, 2016 Joseph Levenson Book Prize, Pre-1900 Category, China and Inner Asia Council of the Association for Asian Studies



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.




Current Topics In Membranes And Transport


Current Topics In Membranes And Transport
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Author :
language : en
Publisher: Academic Press
Release Date : 1987-06-04

Current Topics In Membranes And Transport written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-06-04 with Science categories.


Current Topics in Membranes and Transport