Nanocarriers Based Colon Targeting
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Nanocarriers Based Colon Targeting
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Author : Lalit Kumar
language : en
Publisher: Academic Press
Release Date : 2025-04-01
Nanocarriers Based Colon Targeting written by Lalit Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-01 with Medical categories.
Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies unveils a groundbreaking exploration of nanotechnology's potential in revolutionizing drug delivery for colon-related ailments. Today, an array of colonic diseases, including colorectal cancer, colonic polyps, ulcerative colitis, and inflammatory bowel syndrome, pose significant medical challenges. Conventional methods to deliver drugs to this system prove difficult, with limited efficacy and notable side effects. This book delves into the intricate complexities of colonic diseases, their pathophysiology, and epidemiology to support pharmaceutical scientists in designing better drug delivery systems. Providing a comprehensive overview of the area, the chapters elucidate diverse targeting strategies, from time-dependent to microbiota-based drug delivery systems, and explore receptor-based and magnetically assisted delivery mechanisms. Case studies dissected the working mechanisms behind polymeric nanoparticles, polymersomes, polymeric micelles, solid lipid nanoparticles, and other nanocarrier systems tailored for colon targeting. Additionally, this book explores cuttingedge topics such as gold nanoparticles, supra-magnetic iron oxide nanoparticles, and protein–peptide-based nanoparticles, highlighting their mechanisms, applications, and potential toxicities. Merging an overview of colonic pathophysiology with in-depth reviews of each nanomaterial used for drug delivery and practical case studies, Nanocarriers Based Colon Targeting: Design, Development, Mechanism and Case Studies is a complete reference for pharmaceutical scientists involved in elevating drug delivery precision and therapeutic efficacy in this organ system. Toxicologists, material scientists, research physicians, and regulators can also benefit from the case studies developed by expert authors. - Introduces different colonic diseases and their pathophysiology - Explains the mechanism of action of different nanocarriers in colon targeting - Presents case studies of different nanocarriers in colon targeting
Nanocarriers For Drug Targeting Brain Tumors
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Author : Lalit Kumar
language : en
Publisher: Elsevier
Release Date : 2022-06-21
Nanocarriers For Drug Targeting Brain Tumors written by Lalit Kumar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-21 with Technology & Engineering categories.
Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. - Provides information on the design and development of nanocarriers for targeting brain tumors - Outlines the working principles of different nanocarriers for targeting brain tumors - Includes case studies of different nanocarriers for targeting brain tumors
Nanoparticles And Nanocarriers Based Pharmaceutical Formulations
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Author : Akhlesh K. Jain
language : en
Publisher: Bentham Science Publishers
Release Date : 2022-12-09
Nanoparticles And Nanocarriers Based Pharmaceutical Formulations written by Akhlesh K. Jain and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-09 with Medical categories.
Nanomedicine is a rapidly expanding field because of its benefits over conventional drug delivery technology, as it offers site-specific and target-oriented delivery of therapeutic agents. Nanoparticles and Nanocarriers Based Pharmaceutical Preparations presents a structured summary of recent advances and discoveries in nanomedicine and nanocarrier-based drug delivery. The book covers several key topics in a very simple and easy to understand language. Readers will be familiarized with many types of nanocarriers that have been developed over the past decade, the pharmaceutical formulations composed of organic and inorganic materials as well as their clinical benefits. Chapters are written with the help of authoritative sources of knowledge with the goal of building a foundational understanding of novel drug delivery systems. Since the subject matter is interdisciplinary, it will be of interest to students, teachers and researchers in a broad range of fields, including pharmaceutical sciences, nanotechnology, biomedical engineering and material sciences.
Colon Cancer Diagnosis And Therapy
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Author : Naveen Kumar Vishvakarma
language : en
Publisher: Springer Nature
Release Date : 2021-06-04
Colon Cancer Diagnosis And Therapy written by Naveen Kumar Vishvakarma and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-04 with Medical categories.
Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.
Advanced Drug Delivery Systems For Colonic Disorders
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Author : Harish Dureja
language : en
Publisher: Elsevier
Release Date : 2023-11-04
Advanced Drug Delivery Systems For Colonic Disorders written by Harish Dureja and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-04 with Medical categories.
Advanced Drug Delivery Systems for Colonic Disorders present the current state of the art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters are written in a way that allows the audience to not only become familiar with the most recent advancement in the field, but to better understand them by referring to various illustrations, figures, and informative tables. The contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the current status of clinical trials in the area. Advanced Drug Delivery Systems for Colonic Disorders is the perfect resources for researchers in pharma, biomaterials, and nutrition to familiarize themselves with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications. - Covers recent perspectives and challenges towards the treatment of colonic disorders - Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of colonic disorders - Discusses drug delivery strategies to manage inflammatory bowel disease (chronic inflammation in the digestive tract), ulcerative colitis (inflammation and ulcers in colon), Crohn's disease, Colonic polyps, Shigellosis, Colon Bleeding or Hemorrhage, Diverticulosis and colon cancer
Polysaccharide Based Nano Biocarrier In Drug Delivery
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Author : Tapan Kumar Giri
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Polysaccharide Based Nano Biocarrier In Drug Delivery written by Tapan Kumar Giri and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.
This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.
Multifunctional Nanocomposites For Targeted Drug Delivery In Cancer Therapy
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Author : Awesh K. Yadav
language : en
Publisher: Elsevier
Release Date : 2023-11-24
Multifunctional Nanocomposites For Targeted Drug Delivery In Cancer Therapy written by Awesh K. Yadav and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-24 with Computers categories.
Multifunctional Nanocomposites for Targeted Drug Delivery in Cancer Therapy explores the design, synthesis, and application of different multifunctional nanocomposites drug delivery system for cancer treatment. It encompasses initial chapters discussing introductory information about cancer, followed by chapters focusing on the detailed information about various novel drug delivery systems for treatment of several organ site cancers such as prostate, skin, breast, lung, liver, pancreas, stomach, colon, blood, mouth and throat. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical research who need to understand more about novel nanotechnologies applied to cancer treatment. - Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies - Presents chapters dedicated to each cancer type and the best nanocomposite therapies used, making the content easily discoverable by readers - Written by world-renowned experts and researchers in the areas of nanomedicine, drug delivery and cancer research to explore thoroughly the topic with diverse perspectives
Nanocarriers For Organ Specific And Localized Drug Delivery
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Author : Muhammad Raza Shah
language : en
Publisher: Elsevier
Release Date : 2022-04-08
Nanocarriers For Organ Specific And Localized Drug Delivery written by Muhammad Raza Shah and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-08 with Technology & Engineering categories.
Organ-specific drug delivery is aimed at achieving increased concentration of therapeutic molecules at target sites with minimum side effects on other healthy tissues. Similarly, drug-specific delivery to some vital organs, such as the brain, lungs, heart and kidneys remains a challenging task for the formulation scientists. Oral delivery of most of the commercially available life-saving drugs has also been impeded by various physio-chemical and biological barriers. These advancements in nanotechnology have led to the development of various pharmaceutical nanocarriers.Nanocarriers for Organ-Specific and Localized Drug Delivery summarizes targeted drug delivery systems and approaches to the major organs of the body. The book shows how drugs can be specifically targeted to the pathological area within an organ in a viable way. Employing pharmaceutical nanocarriers for drug delivery targeted to specific organs of the body requires a comprehensive knowledge of the disease site's pathophysiology as well as physical, chemical and pharmaceutical techniques for modification or functionalization of the nanocarriers.Combining theoretical principles and practical applications of various nanocarriers for organ-specific drug delivery, this is an important reference source for all those seeking to increase their understanding of how pharmaceutical nanocarriers are being used to create more efficient drug delivery systems. - Outlines the underlying principles for the design of advanced pharmaceutical nanocarriers for organ specific drug delivery - Includes guidance on how to exploit the pathophysiology and microenvironment of the diseased sites for targeted drug delivery - Assesses the major challenges for creating pharmaceutical nanocarriers on a mass scale
Natural Plant Products In Inflammatory Bowel Diseases
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Author : Roberto de Paula do Nascimento
language : en
Publisher: Elsevier
Release Date : 2023-03-17
Natural Plant Products In Inflammatory Bowel Diseases written by Roberto de Paula do Nascimento and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-17 with Science categories.
Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential organizes all evidence to understand which natural products are the first steps of investigation and which have strong evidence of their effects in inflammatory bowel diseases, have been tested in clinical trials, and have received approval to be officially used. In addition to providing information regarding the research with natural products in inflammatory bowel diseases, this reference will also highlight the molecular mechanisms behind the effects of natural products in inflammatory bowel diseases with the aid of figures, video animations and dynamic tables. Compiled from research group members from different parts of the world and specialized in inflammatory bowel diseases and related topics, this important reference will be useful to health professionals, researchers, professors, and industry managers as it provides helpful information on the subject, with the potential to inspire health care, relevant research and product innovation. - Provides updated information on the pathogenesis of inflammatory bowel diseases and their pharmacological treatments and adverse effects - Delivers the most up-to-date information regarding the molecular mechanisms of natural products in inflammatory bowel diseases - Organizes the separation of natural products based on their characteristics, including lists of the main results of natural products in experiments conducted in vitro with animals, and in humans with IBDs
Applications Of Nanovesicular Drug Delivery
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Author : Amit Kumar Nayak
language : en
Publisher: Academic Press
Release Date : 2022-07-22
Applications Of Nanovesicular Drug Delivery written by Amit Kumar Nayak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-22 with Medical categories.
Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles. This volume will discuss target-specific drug application, such as ocular, transdermal, nasal, intravenous and oral delivery. This title is a valuable resource for academics, pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals and regulatory scientists actively involved in pharmaceutical products and process development of tailored-made polysaccharides in drug delivery applications. Recently, there have been a number of outstanding nanosystems in nanovesicular carrier-forms (such as nanoemulsions, self-nanoemulsifying systems, nanoliposomes, nanotransferosomes, etc.), that have been researched and developed for efficient drug delivery by many formulators, researchers and scientists. However, no previously published books have covered all these drug delivery nanovesicles collectively in a single resource. - Provides thorough insights and up-to-date discussions about the various systems of nanovesicular drug delivery - Covers advanced trigger-assisted systems (such as iontophoresis, ultra-sound triggering, etc.) and how they have been used for improved drug delivery by nanovesicles - Presents recent advances in drug delivery fields by global leaders and experts from academia, research, industry and regulatory agencies - Includes an updated literature review of relevant key topics, good quality illustrations, chemical structures, attractive flow charts and well-organized tables