Natural Selection And Genetic Drift Effects On Neutral Polymorphism
DOWNLOAD
Download Natural Selection And Genetic Drift Effects On Neutral Polymorphism PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Natural Selection And Genetic Drift Effects On Neutral Polymorphism book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Natural Selection And Genetic Drift Effects On Neutral Polymorphism
DOWNLOAD
Author : Sandrine Adiba
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2011-12
Natural Selection And Genetic Drift Effects On Neutral Polymorphism written by Sandrine Adiba and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12 with categories.
The diversity of living organisms is essential for their capacity to evolve and adapt to environmental changes. Therefore, determining the factors responsible for the origin and maintenance of diversity remain central and fundamental research objective. The aim of this book was to understand the evolutionary factors maintaining neutral polymorphism. Using a biological model consisting of the bacterium Escherichia coli and the social amoeba Dictyostelium discoideum enable us to study the natural variability of interactions between the two species. In the second part of this work, we studied the bacterial traits involved in this natural variability. In coevolution experiments, we followed temporal allele frequency variations over 300 bacterial generations under four sets of environmental conditions: with or without biotic factor and with or without spatial structure. The aim of theoretical model we developed was to address the demographic stochasticity effects on neutral allele fixation probability and time to fixation. This book should be useful to professionals in experimentation or theoretical models or anyone else who may be concerning about evolution and population genetics.
The Neutral Theory Of Molecular Evolution
DOWNLOAD
Author : Motoo Kimura
language : en
Publisher: Cambridge University Press
Release Date : 1983
The Neutral Theory Of Molecular Evolution written by Motoo Kimura and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
This book is the first comprehensive treatment of this subject.
Natural Selection And Genetic Drift
DOWNLOAD
Author : Joshua Richardson
language : en
Publisher: Nova Science Publishers
Release Date : 2016
Natural Selection And Genetic Drift written by Joshua Richardson and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Science categories.
Natural selection is the process which, being the most important factor of evolution, promotes rising of adaptability and prevents destructive consequences of all other processes. The concept of natural selection is a discordant problem of evolutionary human genetics. Despite popularity of a hypothesis of "neutral evolution", the majority of scientists consider that selection has played main role in evolution of species and has generated all bio-logical diversity of human populations. This book presents research on natural selection and genetic drift. The author of the first chapter provides an all-embracing macroevolutionary perspective on the processes of the evolution of life and culture on earth. The author investigates a complementary form of natural selection that diverges from the traditional form in that it is acting independently of the external environment. The next chapter discusses natural selection and diabetes mellitus. The last chapter examines how the genetic drift among native people from South American the Gran Chaco region affects interleukin 1 receptor antagonist variation.
Bioinformatics For Beginners
DOWNLOAD
Author : Supratim Choudhuri
language : en
Publisher: Elsevier
Release Date : 2014-05-09
Bioinformatics For Beginners written by Supratim Choudhuri and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-09 with Science categories.
Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available databases. Eschewing non-essential information, the work focuses on principles and hands-on analysis, also pointing to further study options. Avoids non-essential coverage, yet fully describes the field for beginners Explains the molecular basis of evolution to place bioinformatic analysis in biological context Provides useful links to the vast resource of publicly available bioinformatic databases and analysis tools Contains over 100 figures that aid in concept discovery and illustration
Population Genetics Molecular Evolution And The Neutral Theory
DOWNLOAD
Author : Motoo Kimura
language : en
Publisher: University of Chicago Press
Release Date : 1994
Population Genetics Molecular Evolution And The Neutral Theory written by Motoo Kimura and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Science categories.
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Introduction To Natural Selection
DOWNLOAD
Author : Clifford Johnson
language : en
Publisher:
Release Date : 1976
Introduction To Natural Selection written by Clifford Johnson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Science categories.
Genetic systems and fitness; Evidence for selection; The balanced polymorphism, or th non-neutral equilibria; Selection coefficients in natural populations; Varying fitness and the unit of selection; Quantitative traits and the selection effect; Selection in retrospect and prospect.
Population Genetics And Ecology
DOWNLOAD
Author : Samuel Karlin
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Population Genetics And Ecology written by Samuel Karlin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Population Genetics and Ecology is a collection of papers presented at a 1975 conference-workshop held in Israel and is devoted to topics in population genetics and ecology. Contributors discuss topics related to population genetics and ecology, including the determinants of genetic variation in natural populations; experimental design and analysis of field and laboratory data; and theory and applications of mathematical models in population genetics. The book describes a number of field and laboratory studies that focus on a variety of spatial and temporal character and enzyme frequency patterns in natural populations, along with possible associations between these patterns and ecological parameters. This volume is organized into three sections encompassing 31 chapters and begins by summarizing the results of field and laboratory research that investigated gene frequency patterns in space and time of animal and plant populations. This book then explains the origin of new taxa; animal and plant domestication; variation in heritability related to parental age; and problems in the genetics of certain haplo-diploid populations. The next section offers a combination of data analyses and interpretations of related models, with some papers devoted to the origin of race formation and the interaction between sexual selection and natural selection. Among the theoretical studies presented are facets of selection migration interaction; stochastic selection effects; properties of density and frequency dependent selection; concepts and measures of genetic distance and speciation; aspects of altruism; and kin selection. This book will be of interest to naturalists, experimentalists, theoreticians, statisticians, and mathematicians.
The Effects Of Natural Selection And Random Genetic Drift In Structured Populations
DOWNLOAD
Author : Takahiro Maruki
language : en
Publisher:
Release Date : 2011
The Effects Of Natural Selection And Random Genetic Drift In Structured Populations written by Takahiro Maruki and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Evolution (Biology) categories.
Building mathematical models and examining the compatibility of their theoretical predictions with empirical data are important for our understanding of evolution. The rapidly increasing amounts of genomic data on polymorphisms greatly motivate evolutionary biologists to find targets of positive selection. Although intensive mathematical and statistical studies for characterizing signatures of positive selection have been conducted to identify targets of positive selection, relatively little is known about the effects of other evolutionary forces on signatures of positive selection. In this dissertation, I investigate the effects of various evolutionary factors, including purifying selection and population demography, on signatures of positive selection. Specifically, the effects on two highly used methods for detecting positive selection, one by Wright's Fst and its analogues and the other by footprints of genetic hitchhiking, are investigated. In Chapters 2 and 3, the effect of purifying selection on Fst is studied. The results show that purifying selection intensity greatly affects Fst by modulating allele frequencies across populations. The footprints of genetic hitchhiking in a geographically structured population are studied in Chapter 4. The results demonstrate that footprints of genetic hitchhiking are significantly influenced by geographic structure, which may help scientists to infer the origin and spread of the beneficial allele. In Chapter 5, the stochastic dynamics of a hitchhiking allele are studied using the diffusion process of genetic hitchhiking conditioned on the fixation of the beneficial allele. Explicit formulae for the conditioned two-locus diffusion process of genetic hitchhiking are derived and stochastic aspects of genetic hitchhiking are investigated. The results in this dissertation show that it is essential to model the interaction of neutral and selective forces for correct identification of the targets of positive selection.
Populations Genetics Of Humans
DOWNLOAD
Author : Christine Langhoff
language : en
Publisher: GRIN Verlag
Release Date : 2003-06-07
Populations Genetics Of Humans written by Christine Langhoff and has been published by GRIN Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-07 with Science categories.
Essay from the year 2002 in the subject Biology - Genetics / Gene Technology, grade: 2.1 (B), Oxford University (New College), language: English, abstract: The aim of population genetics is to model the dynamics of evolutionary change within and between populations i.e. a group of individuals who exist together in time and space and are capable of interbreeding. In human DNA approximately 0.08% of the nucleotide base pairs varies among individuals and thus populations genetics has been trying to establish why this is so. Four basic evolutionary forces responsible for genetic diversity in populations have been identified: mutation, natural selection, genetic drift and gene flow. Mutations are copying errors during DNA replication and transcriptions, which introduce new alleles into the population. Natural selection is the differential transmission of alleles into the next generation due to the consequences of functional differences on an individual’s survival and reproductive success. Genetic drift is the differential transmission of alleles into the next generation as a result of random sampling and has the greatest potential impact in small populations. Gene flow spreads alleles from one population into another via migration, making them more genetically similar to each other, and countering genetic differentiation by drift. I am going to examine the contribution of genetic drift, gene flow and natural selection to the levels of diversity and composition of genetic polymorphisms in different human populations. Further I am going to examine why some populations have greater diversity than others and compare the patterns of genetic diversity of humans and chimpanzees.
The Causes Of Molecular Evolution
DOWNLOAD
Author : John H. Gillespie
language : en
Publisher: Oxford University Press
Release Date : 1994-05-26
The Causes Of Molecular Evolution written by John H. Gillespie and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-26 with Science categories.
This work provides a unified theory that addresses the important problem of the origin and maintenance of genetic variation in natural populations. With modern molecular techniques, variation is found in all species, sometimes at astonishingly high levels. Yet, despite these observations, the forces that maintain variation within and between species have been difficult subjects of study. Because they act very weakly and operate over vast time scales, scientists must rely on indirect inferences and speculative mathematical models. However, despite these obstacles, many advances have been made. The author's research in molecular genetics, evolution, and bio-mathematics has enabled him to draw on this work, and present a coherent and valuable view of the field. The book is divided into three parts. The first consists of three chapters on protein evolution, DNA evolution, and molecular mechanisms. This section reviews the experimental observations on genetic variation. The second part gives a unified treatment of the mathematical theory of selection in a fluctuating environment. The final two chapters combine the earlier assessments in a treatment of the scientific status of two competing theories for the maintenance of genetic variation. Steeped in the enormous advances population genetics has made over the past 25 years, this book has proven highly popular among human geneticists, biologists, evolutionary theorists, and bio-mathematicians.