Neural Tracing Methods
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Neural Tracing Methods
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Author : Benjamin R. Arenkiel
language : en
Publisher: Humana
Release Date : 2016-09-22
Neural Tracing Methods written by Benjamin R. Arenkiel and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-22 with Medical categories.
This volume seeks to familiarize readers with a diverse range of technologies and approaches for probing neuron and circuit architecture, and, when possible, to attach detailed protocols to help guide readers toward practical application. From classical lipophilic dye and conjugated lectin tracing techniques, to electrophysiological, in vivo imaging, viral tract tracing, and emerging genetic methods to mark, manipulate, and monitor neural circuits, Neural Tracing Methods: Tracing Neurons and Their Connections includes reference to an arsenal of tools and technologies currently being implemented in model systems ranging from flies to mice. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Essential and authoritative, Neural Tracing Methods: Tracing Neurons and Their Connections collects a comprehensive compilation of chapters authored by inventors and expert users, that describes state-of-the-art neuronal tracing and functional analysis methods in order to aid researchers in continuing this vital pathway of study.
Neurocytochemical Methods
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Author : Andre Calas
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Neurocytochemical Methods written by Andre Calas and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
The great strides made in the field of morphological methods during the past decades have perhaps found their most spectacular expression in the functional exploration of the nervous system. In comparison with other tissues, nerve tissue displays three kinds of specificity : structural, because of the unique organization of the neuronal networks ; chemical as shown, for example, by the informative molecules exchanged between the nerve cells, and of course functional, thanks to the particular metabolic and electrophysiological characteristics of the neurons. Although for a long time the structural properties of the nervous system were generally considered to constitute the only field to which morphological techniques could be applied, we are to-day justified in believing that they can also explore the nerve tissue through its specific chemical and functional aspects, thanks to the development of immunocytochemistry and in situ hybridization, to the elaboration of the deoxyglucose method, to the use of voltage or ion sensitive dyes, and to the progress made in the application of in vivo techniques like PET. These methods have evolved so fast, the technical and fundamental problems they raise are so numerous and stimulating, and the importance of the complementary data they provide is so obvious, that we thought it was a good time to organize a new meeting between distinguished specialists in the neurocytochemical field.
Decoding Neural Circuit Structure And Function
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Author : Arzu Çelik
language : en
Publisher: Springer
Release Date : 2017-07-24
Decoding Neural Circuit Structure And Function written by Arzu Çelik and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-24 with Medical categories.
This book offers representative examples from fly and mouse models to illustrate the ongoing success of the synergistic, state-of-the-art strategy, focusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to answer this question: How do individual nerve cells functionally cooperate to guide behavioral responses? Two genetically tractable species, mice and flies, together significantly further our understanding of these processes. Current efforts focus on integrating knowledge gained from three interrelated fields of research: (1) understanding how the fates of different cell types are specified during development, (2) revealing the synaptic connections between identified cell types (“connectomics”) using high-resolution three-dimensional circuit anatomy, and (3) causal testing of how iden tified circuit elements contribute to visual perception and behavior.
Modern Techniques In Neuroscience Research
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Author : Uwe Windhorst
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Modern Techniques In Neuroscience Research written by Uwe Windhorst and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Nothing tends so much to the advancement of knowledge as the application of a new instrument. - Sir Humphry Davy, 1778-1829 Neuroscience has become a rapidly expanding endeavor that relies on a number of other sciences, such as mathematics, physics, chemistry, engineering, computer sci ence, general biology and medicine, genetics etc. In fact, many of its recent success es result from the application of ideas and methods borrowed from these fields. In sofar, it is a true interdisciplinary undertaking. This convergence of influences ac counts for part of its enormous attractiveness and fascination to students and re searchers from diverse walks of life, or science, for that matter. It is probably fair to say that a great number of neuroscience's most creative and productive proponents have been lured into this field not only by the excitement about the possibility to un mask the secrets of the human mind, but also by the appeal of a vast unknown land needing cultivation and tools to cultivate it. Danger may arise for any science if it is dominated by methods and techniques of investigation rather than by problems to be solved and concepts to be developed. This might concentrate efforts onto the technically feasible and doable, rather than On the real issues. But, On the other hand, especially the young and growing sciences are heavily dependent on the development and application of methods, often even before a problem relying on these methods may become apparent.
Insights In Brain Imaging Methods 2023
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Author : Xi-Nian Zuo
language : en
Publisher: Frontiers Media SA
Release Date : 2024-10-04
Insights In Brain Imaging Methods 2023 written by Xi-Nian Zuo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-04 with Science categories.
Following on from the success of Insights in Brain Imaging Methods: 2021, we would like to further celebrate the exceptional achievements made by scientists, leading to major advancements in the fast-growing field of neuroscience. You can find the 2021 edition here. Frontiers is continuing to organize a series of Research Topics to highlight the latest advancements in research across the field of neuroscience, with articles from the members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Prof Vince D Calhoun, Specialty Chief Editor of the Brain Imaging Methods section, together with Professors Federico Giove and Xi-Nian Zuo, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Brain Imaging Methods.
Developing Stem Cell Based Therapies For Neural Repair
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Author : Clare Parish
language : en
Publisher: Frontiers Media SA
Release Date : 2015-01-28
Developing Stem Cell Based Therapies For Neural Repair written by Clare Parish and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-28 with Neural stem cells categories.
Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression and has resulted in significant hope for the successes of stem cell research. The properties of stem cells render them appropriate for cell replacement therapy, endogenous repair, disease modeling as well as high-throughput drug screening and development. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury. This Frontiers Research topic encouraged contributions from the general field of stem cell biology, with a particular emphasis on utilizing these cells to develop new therapies for neural repair. Related articles deal with issues such as: breakthroughs in stem cell proliferation/differentiation methodologies, using pluripotent and neural stem cells for transplantation and endogenous repair, the use of patient derived stem cells for disease modeling, using stem cells for drug discovery as well as the ethical issues related to the use of stem cells.
Neural Regulation In The Vertebrate Endocrine System
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Author : Dodla Sai Prasada Rao
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Neural Regulation In The Vertebrate Endocrine System written by Dodla Sai Prasada Rao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The objective of this volume is to provide recent information on neural regulation in the endocrine system in vertebrates. Classical studies have revealed that certain neurons synthesize and release chemical messengers into the blood vascular system. These neurons are endocrine devices that link the brain with the endocrine glands and other target organs. In vertebrates the hypothalamus is the seat of chemical coordination and integration of environmental and hormonal cues to modulate function of the pituitary, and, consequently, the functions of other endocrine glands. Information generated during the past few decades has resulted in profound alterations in the conceptual fabric of endocrinology. From the wealth of information that emerged on neuropeptides of the central nervous system, and connectivities of various brain centers, it has become clear that several extra-hypothalamic sites are also involved in regulation of hypophysial hormones. This volume is divided into five sections: brain regulation of pituitary, brain GnRH and regulation of pituitary in fish, brain control of growth hormone in fish and birds, brain regulation in mammalian luteinizing hormone, and neural control of other endocrines and the immune system. It is hoped that this volume will prove useful to researchers, teachers, and students involved in research and teaching in neuroendocrinology and comparative endocrinology.
Neuron Signaling In Metabolic Regulation
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Author : Qingchun Tong
language : en
Publisher: CRC Press
Release Date : 2021-06-07
Neuron Signaling In Metabolic Regulation written by Qingchun Tong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-07 with Medical categories.
This book focuses on neuron signaling in the regulation of metabolism and body weight, and especially on methods used in these studies. Obesity and related metabolic syndromes have reached epidemic status, but still are no effective strategies for prevention and treatment. Body weight homeostasis is maintained by balanced food intake and energy expenditure, both of which are under the control of brain neurons. In the recent years, significant progress has been made in identifying specific neurons, neural pathways, and non-neuron cells in feeding regulation, as well as in delineating autonomic nervous systems targeting peripheral metabolic tissues in the regulation of energy expenditure and metabolism. This book reviews recent progress on important neuron signaling for body weight and metabolic regulation and the state-of-the-art methods that has been applied in this field, ranging from animal models with neuron-specific manipulations, pharmacology, optogenetics, in vivo Ca2+ imaging, and viral tracing. Readers will be exposed to latest research frontiers on neuron regulation of metabolism. Key Features Explores the role signaling between neurons plays with respect to metabolism Documents how neurotransmitters affect the regulation of feeding Describes various methods and technologies used to study the neuronal control of metabolism Includes contributions from an international team of leading researchers. Related Titles Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Feltz, A. Physiology of Neurons (ISBN 978-0-8153-4600-5) Zempleni, J. & K. Dakshinamurti, eds. Nutrients and Cell Signaling (ISBN 978-0367-39307-6)
Neural Modeling And Neural Networks
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Author : F. Ventriglia
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Neural Modeling And Neural Networks written by F. Ventriglia and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Research in neural modeling and neural networks has escalated dramatically in the last decade, acquiring along the way terms and concepts, such as learning, memory, perception, recognition, which are the basis of neuropsychology. Nevertheless, for many, neural modeling remains controversial in its purported ability to describe brain activity. The difficulties in "modeling" are various, but arise principally in identifying those elements that are fundamental for the expression (and description) of superior neural activity. This is complicated by our incomplete knowledge of neural structures and functions, at the cellular and population levels. The first step towards enhanced appreciation of the value of neural modeling and neural networks is to be aware of what has been achieved in this multidisciplinary field of research. This book sets out to create such awareness. Leading experts develop in twelve chapters the key topics of neural structures and functions, dynamics of single neurons, oscillations in groups of neurons, randomness and chaos in neural activity, (statistical) dynamics of neural networks, learning, memory and pattern recognition.
Cellular And Molecular Methods In Neuroscience Research
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Author : Adalberto Merighi
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-14
Cellular And Molecular Methods In Neuroscience Research written by Adalberto Merighi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-14 with Medical categories.
There are numerous books on cellular and molecular protocols for general use in cell biology but very few are exclusively devoted to neurobiology. This book fills this gap and explains in a clear and consistent manner, some of the more commonly used protocols in neuroscience research. Each chapter is written by either the person who invented the procedure or an expert in the field. The format is uniform: "Overview," "Background," "Protocols," and "results and discussion." Each protocol begins with the principle of the technique, studies in cell culture, materials and reagents, and, lastly, step-by-step outline of the procedure itself. This highly practical book is also well illustrated (with 17 four color plates) to make the concepts and procedures easy to understand and perform.