Neuro Immuno Physiology Of The Gastrointestinal Mucosa
DOWNLOAD
Download Neuro Immuno Physiology Of The Gastrointestinal Mucosa PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Neuro Immuno Physiology Of The Gastrointestinal Mucosa book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Neuro Immuno Physiology Of The Gastrointestinal Mucosa
DOWNLOAD
Author : Ron H. Stead
language : en
Publisher:
Release Date : 1992
Neuro Immuno Physiology Of The Gastrointestinal Mucosa written by Ron H. Stead and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
Scientists from various disciplines integrate the neuro-biological and immunological aspects of mucosal function in the context of traditional mucosal physiological processes. Coverage includes epithelium-barrier function to antigens, lamina propria-immune and other effector cells, epithelial response to inflammation, epithelial secretory responses to inflammation, interactions of immune cells/mediators with the nervous system, neuro/immune modulation of epithelial function and pathophysiology of inflammation.
Immunophysiology Of The Gut
DOWNLOAD
Author : W. Allan Walker
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Immunophysiology Of The Gut written by W. Allan Walker and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Health & Fitness categories.
Bristol-Myers Squibb/Mead Johnson Nutrition Symposia, Volume 11: Immunophysiology of the Gut represents a comprehensive and systematic coverage of the immunophysiology of the gut, compiling research that integrates the mucosal immune system and intestinal physiology. This book discusses the immunological regulation of epithelial function, fibroblastic sheath, pathways of arachidonic acid metabolism, and gastric response to mucosal anaphylaxis. The implications for inflammatory diarrhea, role of breast milk in neonatal host defense, and milk-borne peptide growth factors in human and bovine milk are also elaborated. This publication likewise covers the immunopathologic features of celiac disease, immune responses in protein-energy malnutrition, and bacterial translocation. This volume is suitable for experts and clinicians from the disciplines of mucosal immunology, intestinal physiology, and enteric neurophysiology.
Immunopharmacology Of The Gastrointestinal System
DOWNLOAD
Author : John L. Wallace
language : en
Publisher: London ; Toronto : Academic Press
Release Date : 1993
Immunopharmacology Of The Gastrointestinal System written by John L. Wallace and has been published by London ; Toronto : Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.
Gastrointestinal And Hepatic Immunology
DOWNLOAD
Author : Richard Heatley
language : en
Publisher: Cambridge University Press
Release Date : 1994-10-27
Gastrointestinal And Hepatic Immunology written by Richard Heatley and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-27 with Medical categories.
This 1994 volume summarizes basic scientific advances in the area of the gut immune system and the immune abnormalities relevant to gastrointestinal and liver disease.
Neuro Immuno Regulation Of Inflammation In The Colonic Mucosa
DOWNLOAD
Author : Maria Teresa Casado Bedmar
language : en
Publisher: Linköping University Electronic Press
Release Date : 2020-11-18
Neuro Immuno Regulation Of Inflammation In The Colonic Mucosa written by Maria Teresa Casado Bedmar and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-18 with Electronic books categories.
Intestinal homeostasis is key to control uptake across the mucosa and protect from harmful substances. Disturbances in the bidirectional communication between the gut and the brain are implicated in irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD), being Crohn’s disease (CD) and ulcerative colitis (UC) the two most common IBD subtypes. Although these chronic bowel-relapsing inflammatory disorders present different histopathology, they share similar pathological features. Both IBS and IBD are characterized by a disrupted intestinal barrier function, a pro-inflammatory chronic condition, and an altered gut-brain axis. Despite all the scientific effort, the sequence or exact combination of events that drive these diseases are still unknown, and so is the exact role of every single component. Growing evidence suggests altered neuro-immune interactions as a pathogenic factor. The general aim of this thesis was to elucidate the potential involvement of mast cells and eosinophils in IBS and IBD, and the neuro-immune intercellular circuit via vasoactive intestinal polypeptide (VIP) that might exacerbate mucosal inflammation and intestinal barrier disruption. Intestinal tissues from IBS, inactive IBD, healthy controls (HC), and murine colitis were collected. Electrophysiological and permeability studies were performed using the ex vivo Ussing chamber technique. Tissues were processed with immunohistological procedures to study cell numbers, activation, location, and interactions in relation to VIP. We demonstrated for the very first time an increased transcellular passage of live commensal and pathogenic bacteria through the colonic mucosa of IBS, identifying VIP as a key regulatory molecule together with mast cells activation. In vitro experiments revealed the ability of VIP to activate mast cells. Image analysis identified VIP-mast cells in closer proximity in IBD patients and murine colitis compared to controls. Communication between mast cells and VIP was shown upregulated in IBD and mice colitis via VIP receptor (VPAC)1. Similarities and differences between HC, IBS, and IBD were further studied. Results indicated a pronounced increased intestinal permeability in UC, even during remission, followed by IBS, compared to healthy controls. Surprisingly, permeability results did not correlate with mast cells, but with eosinophil number and activation. A further image analysis suggested an inhibitory effect of eosinophils and VIP on mast cells and an altered interaction between them under inflammatory conditions. Lastly, intestinal VIP levels were shown to increase in IBD patients after the treatment with biological agents and were suggested as a possible biomarker for biological treatment outcome. This thesis presents novel insights into the regulation of intestinal permeability, as well as into the pathophysiology of IBD and IBS by demonstrating the importance of neuro-immune interactions between mast cells, VIP, and eosinophils. Altogether, our findings have broadened the knowledge of neuro-immune interactions in IBS and IBD and might have the potential to onsight lead to new therapeutic approaches thereby improving the outcomes for patients suffering from these diseases.
Geriatric Gastroenterology
DOWNLOAD
Author : C. S. Pitchumoni
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-26
Geriatric Gastroenterology written by C. S. Pitchumoni and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-26 with Medical categories.
As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.
National Library Of Medicine Current Catalog
DOWNLOAD
Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
Regulatory Mechanisms In Gastrointestinal Function 1995
DOWNLOAD
Author : Timothy S. Gaginella
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Regulatory Mechanisms In Gastrointestinal Function 1995 written by Timothy S. Gaginella and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Regulatory Mechanisms in Gastrointestinal Function includes a collection of contemporary topics in gastrointestinal research. The control of gastroduodenal electrolyte transport and the influence of drugs on bicarbonate secretion are reviewed in detail. The importance of the interactions between calcium and cyclic-AMP in intestinal secretion is emphasized in a comprehensive chapter that systematically addresses each link in the mechanisms that regulate chloride secretion. Other important topics included in the book are neural reflex modulation of intestinal epithelial transport, the influence of the microcirculation on intestinal secretion, and nitric oxide as a mediator of physiologic and pathophysiologic secretion. The expertise of the authors has resulted in a breadth of important contemporary topics covered in depth.
Neuropeptides In Respiratory Medicine
DOWNLOAD
Author : PeterJ. Barnes
language : en
Publisher: Routledge
Release Date : 2017-09-29
Neuropeptides In Respiratory Medicine written by PeterJ. Barnes and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-29 with Science categories.
""This outstanding resource offers comprehensive presentations of the latest basic knowledge and the most advanced research on neuropeptides of the respiratory tract covering the structure, receptors, molecular biology, and function of each important neuropeptide and examining how they relate to disease. Demonstrates the utility of immunohistochemistry, autoradiography, molecular biology, smooth muscle contraction, and glandular secretion for the study of neural function both in vitro and in vivo!
Current Catalog
DOWNLOAD
Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.
First multi-year cumulation covers six years: 1965-70.