Neuroepigenetics And Mental Illness
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Neuroepigenetics And Mental Illness
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Author : Bart P.F. Rutten
language : en
Publisher: Academic Press
Release Date : 2018-07-30
Neuroepigenetics And Mental Illness written by Bart P.F. Rutten and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-30 with Science categories.
Neuroepigenetics and Mental Illness, Volume 158, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series seeks to provide readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, with this release focusing on Neuroepigenetics in mental illness, Neuroepigenetics of development and neurodevelopmental disorder, Neuroepigenetics of aging and age-related neurodegenerative disorders, Neuroepigenetics of prenatal psychological stress, Neuroepigenetics of the HPA axis, Neuroepigenetics of the serotonergic system, and more. Presents updated volumes comprising 15-20 chapters, allowing comprehensive coverage on a topic Uses tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided in each chapter
Epigenetics In Psychiatry
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Author : Jacob Peedicayil
language : en
Publisher: Academic Press
Release Date : 2021-08-21
Epigenetics In Psychiatry written by Jacob Peedicayil and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-21 with Science categories.
Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) Features chapter contributions from international leaders in the field
Neuroepigenomics In Aging And Disease
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Author : Raul Delgado-Morales
language : en
Publisher: Springer
Release Date : 2017-05-18
Neuroepigenomics In Aging And Disease written by Raul Delgado-Morales and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-18 with Science categories.
Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington’s disease) and elderly (Alzheimer’s disease, Parkinson’s disease). The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on neuronal function and behavior. Finally, a special chapter on state-of-the-art technologies helps the reader not only to understand epigenetic driven changes in human cognition and diseases but also the methodology that will help to generate paradigm shifts on our understanding of brain function and the role of the neuroepigenome in human diseases.
Arousal In Neurological And Psychiatric Diseases
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Author : Edgar Garcia-Rill
language : en
Publisher: Academic Press
Release Date : 2019-06-18
Arousal In Neurological And Psychiatric Diseases written by Edgar Garcia-Rill and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-18 with Medical categories.
Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders Covers multiple neurological disorders, including epilepsy, Alzheimer’s disease, Parkinson’s disease and autism
The Epigenetics Revolution
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Author : Nessa Carey
language : en
Publisher: Columbia University Press
Release Date : 2012-03-06
The Epigenetics Revolution written by Nessa Carey and has been published by Columbia University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-06 with Science categories.
Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Charney Nestler S Neurobiology Of Mental Illness
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Author : Dennis S. Charney
language : en
Publisher: Oxford University Press
Release Date : 2018
Charney Nestler S Neurobiology Of Mental Illness written by Dennis S. Charney and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Medical categories.
Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.
Comprehensive Women S Mental Health
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Author : David J. Castle
language : en
Publisher: Cambridge University Press
Release Date : 2016-03-07
Comprehensive Women S Mental Health written by David J. Castle and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-07 with Medical categories.
A comprehensive, up-to-date and evidence-based review of women's mental health, written by leading experts, for mental health clinicians.
Microbes And The Mind
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Author : C.S.M. Cowan
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2021-05-06
Microbes And The Mind written by C.S.M. Cowan and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-06 with Medical categories.
Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.
Epigenetic Regulation In The Nervous System
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Author : J. David Sweatt
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Epigenetic Regulation In The Nervous System written by J. David Sweatt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions. Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia. BMA Medical Book Awards 2014 - Highly Commended, Neurology, British Medical Association BMA Medical Book Awards 2014 - First Prize, Neurology, British Medical Association 2013 PROSE Award winner for Best in Reference Works and Best Single Volume Reference in Science from the Association of American Publishers Presents a unified view of epigenetic mechanisms from behavior to genes and everything in between Discusses clinically relevant disorders in the context of epigenetics research, making the volume appealing to clinicians as well as basic scientists Provides numerous practical examples for the new investigator to facilitate implementation of research in neuroepigenetics
Neurobiology Of Mental Illness
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Author : Dennis S. Charney
language : en
Publisher: Oxford University Press
Release Date : 2013-06-25
Neurobiology Of Mental Illness written by Dennis S. Charney and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-25 with Medical categories.
Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers, doctoral students, and postdoctoral fellows the neurosciences.