Neurogenesis In The Adult Brain Ii
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Neurogenesis In The Adult Brain Ii
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Author : Tatsunori Seki
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-15
Neurogenesis In The Adult Brain Ii written by Tatsunori Seki and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-15 with Medical categories.
The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.
Neurogenesis In The Adult Brain I
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Author : Tatsunori Seki
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-15
Neurogenesis In The Adult Brain I written by Tatsunori Seki and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-15 with Medical categories.
The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.
Adult Neurogenesis
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Author : Gerd Kempermann
language : en
Publisher: Oxford University Press, USA
Release Date : 2006
Adult Neurogenesis written by Gerd Kempermann and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Adulthood categories.
The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the mature brain. Though we now know that the adult brain can make new neurons, it normally does so only in two privileged regions, the olfactory bulb and the hippocampus. Yet stem cells, which have the potential to produce new neurons, can be found throughout the adult brain. So why does the brain not make wider use of its potential for neurogenesis? And what is the function of new neurons and of neural stem cells in areas where they occur? After all, the brain regenerates poorly and many neurological and psychiatric disorders are chronic because cell replacement has not taken place. This is the first comprehensive, integrated account of one of the most exciting areas of neuroscience. It begins with the historical background and discusses theories of adult neurogenesis and neural stem cell biology in the context of learning and memory processes as well as structural plasticity. It describes in detail neurogenesis in the adult hippocampus and olfactory system and then surveys the regulatory, functional, and comparative aspects, concluding with a chapter on the provocative hypotheses that link failing adult neurogenesis with such diseases as temporal lobe epilepsy, major depression, brain tumors, and dementias. For graduate students, investigators, and clinicians in the neurosciences, developmental biology, and stem cell research, this book is a unique resource that sifts through the evidence for exciting scientific ideas and fosters a realistic view of the therapeutic possibilities for the use of stem cells in the adult brain.
Neurogenesis In The Adult Brain
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Author : Alfred Carter
language : en
Publisher: Murphy & Moore Publishing
Release Date : 2021-11-16
Neurogenesis In The Adult Brain written by Alfred Carter and has been published by Murphy & Moore Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
Neurogenesis refers to the process of production of neurons by neural stem cells. There are different types of neural stem cells such as radial glial cells, neuroepithelial cells, intermediate neuronal precursors, basal progenitors, subgranular zone radial astrocytes and subventricular zone astrocytes. Neural stem cells are self-renewing and multipotent cells. Neurogenesis is responsible for producing all the different types of neurons within an individual. It is most active during embryonic development but continues throughout adult life. Adult neurogenesis is different from prenatal neurogenesis. Formation of new neurons in adults takes place in two regions of the brain, namely, subgranular zone and subventricular zone. This book strives to provide a fair idea about neurogenesis in adult brain and helps to develop a better understanding of the latest advances within this field. It presents researches and studies performed by experts across the globe. This book will serve as a valuable source of reference for graduate and post graduate students.
Adult Neurogenesis In The Hippocampus
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Author : Juan J. Canales
language : en
Publisher: Academic Press
Release Date : 2016-05-23
Adult Neurogenesis In The Hippocampus written by Juan J. Canales and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-23 with Science categories.
Neurogenesis in the adult brain has emerged as one of the most dynamic and rapidly moving fields in modern neuroscience research. The implications of adult neurogenesis for health and well-being are wide-ranging, with findings in this area having distinct relevance for treatment and rehabilitation in neurology and psychopathology. Adult Neurogenesis in the Hippocampus addresses these implications by providing an up-to-date account on how neurogenesis in the adult hippocampus contributes to critical psychological and physiological processes, such as learning and memory, and how it is modified by life experiences, such as aging, environmental enrichment, exercise, and dieting. The book also provides the most current reviews of how adult hippocampal neurogenesis influences the pathogenesis of mood disorders, addiction, and key neurological disorders. This book is the ideal resource for researchers and advanced graduates seeking focused knowledge on the role of adult neurogenesis in brain health and disease. Provides a unique overview of how adult hippocampal neurogenesis contributes to adaptive processes, brain psychopathology, and disease Includes state-of-the-art reviews by leading world experts in adult neurogenesis
Adult Neurogenesis Beyond Rats And Mice
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Author : Luca Bonfanti
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-11
Adult Neurogenesis Beyond Rats And Mice written by Luca Bonfanti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-11 with categories.
Researchers working on adult neurogenesis have focused largely on inbred laboratory rodents. While this provides a strong advantage of restricting genetic variation in the group, it also narrows our perspective on adult neurogenesis as a biological phenomenon. Many unsolved issues and open questions cannot be resolved without the contribution of comparative studies spanning through widely different species: how did adult neurogenesis evolve, what is the link between adult neurogenesis and brain complexity, how do adult neurogenesis and animal behavior influence each other, how does adult neurogenesis contribute to brain plasticity, cognition and, possibly, repair, and how do experimental conditions affect adult neurogenesis. The main message from the comparative approach to adult neurogenesis is that the relative exclusive focus on laboratory rodents can result in a bias on how we think about this biological process.
Adult Neurogenesis
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Author :
language : en
Publisher:
Release Date : 2011
Adult Neurogenesis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Developmental neurobiology categories.
50th Anniversary Of Adult Neurogenesis Olfaction Hippocampus And Beyond
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Author : Alino Martinez-Marcos
language : en
Publisher: Frontiers Media SA
Release Date : 2016-09-21
50th Anniversary Of Adult Neurogenesis Olfaction Hippocampus And Beyond written by Alino Martinez-Marcos and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-21 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
In the mid-sixties, the discovery by Altman and co-workers of neurogenesis in the adult brain changed the previous conception of the immutability of this organ during adulthood sustained among others by Cajal. This discovery was ignored up to eighty’s when Nottebohm demonstrated neurogenesis in birds. Subsequently, two main neurogenic zones were characterized: the subventricular zone of the lateral ventricle and the subgranular layer of the dentate gyrus. Half century later, the exact role of new neurons in the adult brain is not completely understand. This book is composed by a number of articles by leaders in the filed covering from an historic perspective to potential therapeutic opportunities.
Neurogenesis And Neural Plasticity
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Author : Catherine Belzung
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08
Neurogenesis And Neural Plasticity written by Catherine Belzung and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Medical categories.
This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.
Adult Neurogenesis Twenty Years Later Physiological Function Versus Brain Repair
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Author : Paolo Peretto
language : en
Publisher: Frontiers Media SA
Release Date : 2015-05-01
Adult Neurogenesis Twenty Years Later Physiological Function Versus Brain Repair written by Paolo Peretto and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-01 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
The discovery that mammalian brains contain neural stem cells which perform adult neurogenesis - the production and integration of new neurons into mature neural circuits - has provided a fully new vision of neural plasticity. On a theoretical basis, this achievement opened new perspectives for therapeutic approaches in restorative and regenerative neurology. Nevertheless, in spite of striking advancement concerning the molecular and cellular mechanisms which allow and regulate the neurogenic process, its exploitation in mammals for brain repair strategies remains unsolved. In non-mammalian vertebrates, adult neurogenesis also contributes to brain repair/regeneration. In mammals, neural stem cells do respond to pathological conditions in the so called "reactive neurogenesis", yet without substantial regenerative outcome. Why, even in the presence of stem cells in the brain, we lack an effective reparative outcome in terms of regenerative neurology, and which factors hamper the attainment of this goal? Essentially, what remains unanswered is the question whether (and how) physiological functions of adult neurogenesis in mammals can be exploited for brain repair purposes.