Neuromodulatory Control Of Brainstem Function In Health And Disease

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Neuromodulatory Control Of Brainstem Function In Health And Disease

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Author : Brian R. Noga
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-25

Neuromodulatory Control Of Brainstem Function In Health And Disease written by Brian R. Noga and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with categories.

Neuromodulatory Control Of Spinal Function In Health And Disease

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Author : Brian R. Noga
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-20

Neuromodulatory Control Of Spinal Function In Health And Disease written by Brian R. Noga and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-20 with categories.

Neuromodulatory Control Of Brainstem Function In Health And Disease

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Author : Brian R. Noga
language : en
Publisher:
Release Date : 2020

Neuromodulatory Control Of Brainstem Function In Health And Disease written by Brian R. Noga and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.

The brainstem is a conduit connecting higher brain centers, cerebellum and spinal cord and provides the main sensory and motor innervation to the face, head and neck via the cranial nerves. It plays a pivotal role in the regulation of respiration, locomotion, posture, balance, arousal (alertness, awareness and consciousness), sensory information processing (nociception, etc.), autonomic functions (including control of bowel, bladder, blood pressure and heart rate) and is responsible for the regulation of numerous reflexes including swallowing, coughing and vomiting. It is controlled by higher brain centers originating from cortical and subcortical regions including the basal ganglia and diencephalon as well as feedback loops from the cerebellum and spinal cord. A modulatory control of brainstem output can be accomplished by affecting individual neurons and consequently, the operation of neural microcircuits and behavior. This is achieved by altering cellular excitability, synaptic transmission (release probability, postsynaptic receptor responsiveness, thus altering synaptic strength and efficacy) and network properties. Such dynamic control provides flexibility of the nervous system to adapt neural output according to the functional requirements and/or demands of the individual to achieve the desired behavioral state in a changing environment. Neuromodulation can be achieved by the "classical" neurotransmitters glutamate and GABA (gamma-amino butyric acid) by primary excitation and inhibition of the "anatomical network", but can also be achieved through the use of transmitters acting on G- protein coupled receptors. Such neuromodulators include the monoamines (serotonin, noradrenaline and dopamine), acetylcholine, but also glutamate and GABA. In addition, neuropeptides and purines act as neuromodulators. Other chemical mediators such as nitric oxide and growth factors may also have similar actions. The aim of this Research Topic is to highlight recent advances in our understanding of the intrinsic and extrinsic neuromodulatory systems affecting brainstem function from the anatomical, physiological and pharmacological perspective and to emphasize how these advances strengthen, modify or challenge existing conceptual models of sensorimotor and autonomic control.

Brain Neurotrauma

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Author : Firas H. Kobeissy
language : en
Publisher: CRC Press
Release Date : 2015-02-25

Brain Neurotrauma written by Firas H. Kobeissy and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-25 with Medical categories.

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.

Stress And Health

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Author : William R. Lovallo
language : en
Publisher: SAGE Publications
Release Date : 2015-01-29

Stress And Health written by William R. Lovallo and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-29 with Psychology categories.

Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.

Non Invasive Neuromodulation Of The Central Nervous System

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2015-11-02

Non Invasive Neuromodulation Of The Central Nervous System written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-02 with Medical categories.

Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, clinicians,health systems, payers, and industry. Evidence suggests that both therapeutic and non-therapeutic applications of non-invasive neuromodulation will continue to expand in coming years, particularly for indications where treatments are currently insufficient, such as drug-resistant depression. Given the growing interest in non-invasive neuromodulation technologies, the Institute of Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop, inviting a range of stakeholders - including developers of devices and new technologies, researchers, clinicians, ethicists, regulators, and payers - to explore the opportunities, challenges, and ethical questions surrounding the development, regulation, and reimbursement of these devices for the treatment of nervous system disorders as well as for non-therapeutic uses, including cognitive and functional enhancement. This report highlights the presentation and discussion of the workshop.

Translational Research In Traumatic Brain Injury

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Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2016-04-21

Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Discovering The Brain

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Author : National Academy of Sciences
language : en
Publisher: National Academies Press
Release Date : 1992-01-01

Discovering The Brain written by National Academy of Sciences and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-01 with Medical categories.

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Modern Approaches To Augmentation Of Brain Function

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Author : Ioan Opris
language : en
Publisher: Springer Nature
Release Date : 2021-08-25

Modern Approaches To Augmentation Of Brain Function written by Ioan Opris and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.

This book covers recent advances in neural technology that provide for enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits involved in perception, cognition, emotion and action, that represent the building blocks of behavior and cognition. Augmentation of brain function can be achieved by using brain implants for recordings, stimulation, or drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. This volume evaluates existing methods of brain augmentation while discussing the brain circuitry and neuronal mechanisms that make augmentation possible. This volume offers novel insights into brain disorders, and explores new devices for brain repair while also addressing the philosophical and ethical implications of brain augmentation. The information in this book is relevant to researchers in the fields of neuroscience, engineering, and clinical practice. Advance Praise for Modern Approaches to Augmentation of Brain Function: “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” Ray Kurzweil, best-selling author, inventor, entrepreneur and a recipient of the National Medal of Technology and Innovation (1999), and the Lemelson-MIT Prize (2001) "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " Ioan Dumitrache, Prof. Dr. Eng. Faculty of Computer Science, Polytechnic University of Bucharest, Bucharest, Romania “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” György Buzsáki, MD, PhD is the Biggs Professor of Neuroscience, NYU School of Medicine, New York, NY

Neuronal Networks In Brain Function Cns Disorders And Therapeutics

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Author : Carl Faingold
language : en
Publisher: Academic Press
Release Date : 2013-12-26

Neuronal Networks In Brain Function Cns Disorders And Therapeutics written by Carl Faingold and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-26 with Medical categories.

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available