Neuroproteomics Insight Into Brain Function And Disease


Neuroproteomics Insight Into Brain Function And Disease
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Neuroproteomics Insight Into Brain Function And Disease


Neuroproteomics Insight Into Brain Function And Disease
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Author : Tija Carey Jacob
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-05

Neuroproteomics Insight Into Brain Function And Disease written by Tija Carey Jacob and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-05 with Science categories.




Current Proteomic Approaches Applied To Brain Function


Current Proteomic Approaches Applied To Brain Function
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Author : Enrique Santamaría
language : en
Publisher: Humana
Release Date : 2018-08-07

Current Proteomic Approaches Applied To Brain Function written by Enrique Santamaría and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-07 with Medical categories.


This volume focuses on protein analysis covering a wide spectrum of the utility of mass spectrometry within neurobiological disciplines. The chapters in this book discuss label (iTRAQ, TMT, protein arrays) and label-free workflows (SWATH, MALDI Imaging, and label-free quantitation). Other chapters look at experimental strategies targeted to the identification and quantitation of specific lipids and post-translational modifications, as well as proteomic workflows that focus on characterization of subcellular proteomes. The last few chapters in the book describe various bioinformatics pipelines used to analyze the molecular data derived from high-throughput transcriptomic and proteomic experiments on brain tissue. The Neuromethods series offers chapters with key advice and procedure specifics to empower the readers to successfully achieve their own scientific and experimental goals. Thorough and comprehensive, Current Proteomic Approaches Applied to Brain Function is a valuable resource for graduate students and postdoctoral fellows interested in neuroproteomics, as well as researchers looking for further insight into the growing field of mass spectrometry in neuroscience.



Neuroproteomics


Neuroproteomics
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Author : Ka Wan Li
language : en
Publisher: Humana Press
Release Date : 2016-08-23

Neuroproteomics written by Ka Wan Li and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.


In the past few years, the application of proteomics to examine the molecular mechanisms underlying (mal-)functioning of the nervous system and brain disorders has risen steeply, which in many cases has yielded novel insights. As neuroproteomics is a new research field involving the use of a number of high-end analytical instruments and technologies, both promises and pitfalls may not be well appreciated by the researchers, and the design of a proper proteomics experiment may not be obvious. Neuroproteomics brings together a collection of detailed protocols written by experienced professionals in the field in order to cover aspects of various dimensions of this new technology, together with some established methods that have supporting roles in the workflow of neuroproteomics. Written for the popular Neuromethods series, the chapters in this book contain step-by-step, easy to follow instruction along with practical tips and key implementation advice essential for successful implementation of the techniques. Authoritative and cutting-edge, Neuroproteomics will be of great assistance to all researchers seeking to design and execute their own proteomics experiments in an optimal way and continue moving forward this exciting area of study.



Neuroproteomics


Neuroproteomics
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Author : Oscar Alzate
language : en
Publisher: CRC Press
Release Date : 2009-10-26

Neuroproteomics written by Oscar Alzate and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-26 with Medical categories.


In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg



Subcellular Proteomics


Subcellular Proteomics
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Author : Eric Bertrand
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-29

Subcellular Proteomics written by Eric Bertrand and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-29 with Science categories.


This volume summarizes the new developments that made subcellular proteomics a rapidly expanding area. It examines the different levels of subcellular organization and their specific methodologies. In addition, the book includes coverage of systems biology that deals with the integration of the data derived from these different levels to produce a synthetic description of the cell as a system.



Neuroproteomics


Neuroproteomics
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Author : Angus C. Nairn
language : en
Publisher: MDPI
Release Date : 2020-02-12

Neuroproteomics written by Angus C. Nairn and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-12 with Science categories.


The Neuroproteomics Special Issue overviews the unique challenges that must be addressed to carry out meaningful MS/proteomics analyses on neural tissues and the technologies that are available to meet these challenges. The articles on Alzheimer’s disease, addiction, and schizophrenia illustrate how MS/proteomics technologies can be used to improve our ability to diagnose and understand the molecular basis for neurological diseases. Several articles will be of interest to investigators beyond the field of neurological disorders. The review on the discovery of biofluid biomarkers of neurodegenerative dementias will be of interest to investigators searching for other disease biomarkers. Similarly, the review on the role of neuroproteomics in elucidating mechanisms of drug addiction provides an overview of the utility of MS/proteomics approaches for addressing critical questions in addiction neuroscience that should be applicable to investigators involved in virtually any area of biomedical research. Likewise, the article on developing targeted MS approaches for quantifying postsynaptic density proteins will be useful for any investigator who wishes to design targeted assays for virtually any protein. Finally, the peroxidase-mediated proximity labeling technology, described in the article on mapping the proteome of the synaptic cleft, will be of interest to investigators interested in mapping other spatially restricted proteomes.



Neuroproteomics As A Tool For Understanding Schizophrenia


Neuroproteomics As A Tool For Understanding Schizophrenia
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Author : Daniel Martins-de-Souza
language : en
Publisher: Springer Nature
Release Date : 2022-08-05

Neuroproteomics As A Tool For Understanding Schizophrenia written by Daniel Martins-de-Souza and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-05 with Science categories.


Over the past decade, neuroproteomics has shed light on the molecular features of schizophrenia by depicting biological processes involved with its establishment, maintenance and treatment. These studies have also pointed to potential biomarkers applicable to diagnosis and medication monitoring. Edited by a leader in the field of neuroproteomics with contributions from subject experts, this new volume will address recent findings and compile evidence from difference perspectives—such as human samples, animal models, pluripotent stem cell-derived in vitro pre-clinical models—and provide findings to inform the development of innovative future treatment strategies. This volume will be useful for a broad audience of researchers and professionals, including biologists, neurologists, psychiatrists, analytical chemists, and pharmacists, among others.



Multi Omics For The Understanding Of Brain Diseases


Multi Omics For The Understanding Of Brain Diseases
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Author :
language : en
Publisher:
Release Date : 2021-12-13

Multi Omics For The Understanding Of Brain Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-13 with Science categories.




Translational Neuroscience


Translational Neuroscience
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Author : Mark H. Tuszynski
language : en
Publisher: Springer
Release Date : 2016-03-08

Translational Neuroscience written by Mark H. Tuszynski and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-08 with Medical categories.


Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.



Brain Injury


Brain Injury
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Author : Amit Agrawal
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-23

Brain Injury written by Amit Agrawal and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-23 with Medical categories.


The present two volume book "Brain Injury" is distinctive in its presentation and includes a wealth of updated information on many aspects in the field of brain injury. The Book is devoted to the pathogenesis of brain injury, concepts in cerebral blood flow and metabolism, investigative approaches and monitoring of brain injured, different protective mechanisms and recovery and management approach to these individuals, functional and endocrine aspects of brain injuries, approaches to rehabilitation of brain injured and preventive aspects of traumatic brain injuries. The collective contribution from experts in brain injury research area would be successfully conveyed to the readers and readers will find this book to be a valuable guide to further develop their understanding about brain injury.