New Therapies To Prevent Or Cure Auditory Disorders
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New Therapies To Prevent Or Cure Auditory Disorders
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Author : Sylvie Pucheu
language : en
Publisher: Springer Nature
Release Date : 2020-03-25
New Therapies To Prevent Or Cure Auditory Disorders written by Sylvie Pucheu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with Medical categories.
Hearing loss is the most common form of sensory impairment in humans, affecting 360 million persons worldwide. In parallel, tinnitus disorder, the perception of a phantom sound often described as a ringing or buzzing, affects around 10–15% of the general population and interferes with daily life. Hyperacusis, defined as a hypersensitivity to moderate-intensity sounds often co-occurs with tinnitus suggesting a common mechanism of dysfunction for these two perceptual disorders. Whereas some drug candidates are in the process of being developed, nowadays no effective treatment exists to cure hearing loss and tinnitus. The topic of this book was selected with the goal of emphasizing mechanisms that induce hearing loss and tinnitus which lead the selection of promising targets for hearing disorder treatment. Hair cells (HC) are the sensory cells of the inner ear required for both auditory and vestibular functions in all vertebrates. HC are progressively lost during ageing and they are in addition sensitive to physical and acoustic traumas, infectious diseases and chemicals present in commonly used treatments such as anticancer, antimalarial or antibiotics. As adult mammals--including humans--cannot regenerate dead HC, all the possible injury could result in irreversible and permanent hearing loss. It has been shown, however, that a limited capacity to regenerate HC exists in mouse at an early stage of development. The regenerative capacity of HC then appears simply “repressed” in adult mammals, and one could expect it will be possible to re-activate it with an appropriate therapeutic approach which is still to be defined. Immune-mediated inner ear disease has been introduced and accepted as one SNHL pathophysiology; it responds to immunosuppressive therapy and is one of the few reversible forms of bilateral SNHL. Macrophages are always present in the spiral ligament of the lateral wall and are activated in response to various types of stimuli, including noise exposure, ischemia, mitochondrial damage, and surgical stress. Recent studies have also revealed another type of immune cell, called perivascular melanocyte-like macrophages (PVM/Ms), in the stria vascularis. The book will include a review of inflammatory/immune cells in the cochlear lateral wall, the pathways involved in cochlear damage and their potential as therapeutic targets. The final chapter provides an overview of current animal model of tinnitus and hyperacusis. Nowadays no effective treatment exists to cure tinnitus and hyperacusis. One major obstacle to arises from the fact that tinnitus is a subjective phenomenon, the only possible diagnosis relies on self-reports of the subjects. The main constraint of the use of animal models is the subjective character of tinnitus. This chapter describe the advancement in animal models which play an important role in revealing the underlying mechanisms and treatment for tinnitus and hyperacusis.
Hearing Loss Mechanisms Prevention And Cure
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Author : Huawei Li
language : en
Publisher: Springer
Release Date : 2019-03-26
Hearing Loss Mechanisms Prevention And Cure written by Huawei Li and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-26 with Medical categories.
This book systematically discusses the pathogenesis, prevention, and the current and potential clinical treatment of hearing loss, as well as the latest advances in hearing research. Hearing loss is a prevalent sensory disorder, which according to a 2015 World Health Organization (WHO) report affected 9% of the global population in 2015. As populations continue to age, more and more people are suffering from the condition, with 60% of those aged between 65 and 75 affected. Hearing loss seriously affects patients’ ability to work ability and quality of life, and as such deafness has become an increasingly urgent social problem around the globe. Sensorineural hearing loss is mainly caused by damage to the hair cells (HCs), and the subsequent loss of spiral ganglion neurons (SGNs). Damage to the HCs in the inner ear can result from exposure to loud noises and environmental and chemical toxins as well as genetic disorders, aging, and certain medications. This book provides ENT specialists and researchers, as well as individuals affected a comprehensive introduction to the field of hearing loss.
Audiology Treatment
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Author : Michael Valente
language : en
Publisher: Thieme
Release Date : 2011-01-01
Audiology Treatment written by Michael Valente and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-01 with Medical categories.
From the principles of hearing aid instrumentation, selection, and fitting, to the medical and surgical management of ear diseases and hearing disorders, to the rehabilitation of the patient with hearing loss, the new edition of Audiology: Treatment is an invaluable, up-to-date resource for the latest approaches to treating hearing disorders. Organized into two main sections, the book begins by guiding the reader through the principles of treatment and then presents important applications for the clinical setting. Features: Insights from respected experts in the field New chapters on the numerous advances in hearing aid technology and electroacoustic analysis of hearing aids; the importance of outcome measures in validating the performance of amplification; treatment options for patients with processing disorders; new signals for real ear measures; and the use of fully implantable devices Chapter outlines to rapidly acquaint reader with topics to be discussed Pearls, pitfalls, controversial points, and special considerations providing recommendations and comments on key aspects of patient care Audiology: Treatment is one part of a three-volume series, which is completed by Audiology: Diagnosis and Audiology: Practice Management. Together these books provide audiologists and students in graduate programs with a complete compendium of information on optimizing patient care.
Hearing Loss
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Author : Jos J. Eggermont
language : en
Publisher: Academic Press
Release Date : 2017-02-22
Hearing Loss written by Jos J. Eggermont and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-22 with Medical categories.
Hearing Loss: Causes, Prevention, and Treatment covers hearing loss, causes and prevention, treatments, and future directions in the field, also looking at the cognitive problems that can develop. To avoid the “silent epidemic of hearing loss, it is necessary to promote early screening, use hearing protection, and change public attitudes toward noise. Successful treatments of hearing loss deal with restoring hearing sensitivity via hearing aids, including cochlear, brainstem, or midbrain implants. Both the technical aspects and effects on the quality of life of these devices are discussed. The integration of all aspects of hearing, hearing loss, prevention, and treatment make this a perfect one-volume course in audiology at the graduate student level. However, it is also a great reference for established audiologists, ear surgeons, neurologists, and pediatric and geriatric professionals. Presents an in-depth overview of hearing loss, causes and prevention, treatments, and future directions in the field Written for researchers and clinicians, such as auditory neuroscientists, audiologists, neurologists, speech pathologists, pediatricians, and geriatricians Presents the benefits and problems with hearing aids and cochlear implants Includes important quality of life issues
Audiology Treatment
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Author : Jason A. Galster
language : en
Publisher: Thieme Medical Publishers
Release Date : 2019
Audiology Treatment written by Jason A. Galster and has been published by Thieme Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Audiology categories.
The definitive guide to treating hearing loss and auditory disorders in the 21st century Hearing loss impacts an estimated 360 million people worldwide and may precipitate poorer academic performance, reduced quality of life, decreased social engagement, and increased fatigue. Audiology Treatment, Third Edition by Jason Galster and a cadre of renowned audiology experts, is updated in full color with 180 illustrations and new topics. Pearls, best practices, and pitfalls on the management and treatment of hearing loss reflect significant knowledge gleaned from the authors' collective experience. The book is a one-stop resource on hearing aids, covering the many scientific aspects of hearing loss and devices, fitting and measuring patients, and methods to ensure optimal performance over time. In-depth chapters cover the treatment of auditory disorders in children to older adults, including assessments, hearing aid coupling, real-ear measurements, and case studies. Key Highlights Physical properties of hearing aids, verification of acoustic performance, methods of audio signal processing to shape and filter sound, and a detailed introduction to prescription devices Clinical outcome measures utilizing quality-of-life, costs analyses, and evidence-based methods The expanded use of cochlear implants in children and adults Unique topics such as bone-anchored hearing aids, assistive technologies, hearing protection, and management of tinnitus and hyperacusis This title is part of a three-volume set on Audiology (Diagnosis, Treatment, and Practice Management). Together, these books cover every aspect of audiology, providing a remarkably comprehensive resource - essential reading for doctoral students in audiology and must-have bookshelf references for audiologists.
Hearing Health Care For Adults
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2016-10-06
Hearing Health Care For Adults written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-06 with Medical categories.
The loss of hearing - be it gradual or acute, mild or severe, present since birth or acquired in older age - can have significant effects on one's communication abilities, quality of life, social participation, and health. Despite this, many people with hearing loss do not seek or receive hearing health care. The reasons are numerous, complex, and often interconnected. For some, hearing health care is not affordable. For others, the appropriate services are difficult to access, or individuals do not know how or where to access them. Others may not want to deal with the stigma that they and society may associate with needing hearing health care and obtaining that care. Still others do not recognize they need hearing health care, as hearing loss is an invisible health condition that often worsens gradually over time. In the United States, an estimated 30 million individuals (12.7 percent of Americans ages 12 years or older) have hearing loss. Globally, hearing loss has been identified as the fifth leading cause of years lived with disability. Successful hearing health care enables individuals with hearing loss to have the freedom to communicate in their environments in ways that are culturally appropriate and that preserve their dignity and function. Hearing Health Care for Adults focuses on improving the accessibility and affordability of hearing health care for adults of all ages. This study examines the hearing health care system, with a focus on non-surgical technologies and services, and offers recommendations for improving access to, the affordability of, and the quality of hearing health care for adults of all ages.
Magnesium In The Central Nervous System
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Author : Robert Vink
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Magnesium In The Central Nervous System written by Robert Vink and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Hearing Loss From Pathogenesis To Treatment
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Author : Zuhong He
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-05
Hearing Loss From Pathogenesis To Treatment written by Zuhong He and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-05 with Science categories.
Brief Interventions For Psychosis
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Author : Basant Pradhan
language : en
Publisher: Springer
Release Date : 2016-06-10
Brief Interventions For Psychosis written by Basant Pradhan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-10 with Medical categories.
This book offers a clinical guide that brings together a broad range of brief interventions and their applications in treating psychosis. It describes two core approaches that can narrow the current, substantial gap between the need for psychotherapeutic interventions for all individuals suffering from psychosis, and the limited mental health resources available. The first approach involves utilizing the standard therapeutic modalities in the context of routine clinical interactions after adapting them into brief and effective formats. To that end, the book brings in experts on various psychotherapeutic modalities, who discuss how their particular modality could be adapted to more effectively fit into the existing system of care delivery. The second approach, addressed in detail, is to extend the availability of these brief interventions by utilizing the circle of providers as well as the social circle of the clients so that these interventions can be provided in a coordinated and complementary manner by psychiatrists, psychologists, clinical social workers, case managers, peer support specialists and other providers on the one hand, and by family members, friends, social and religious institutions on the other.
Cognitive Behavioral Therapy For Tinnitus
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Author : Eldré W. Beukes
language : en
Publisher: Plural Publishing
Release Date : 2020-10-28
Cognitive Behavioral Therapy For Tinnitus written by Eldré W. Beukes and has been published by Plural Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-28 with Medical categories.
For many individuals afflicted with tinnitus, the condition causes substantial distress. While there is no known cure for tinnitus, cognitive behavioral therapy (CBT) can offer an effective strategy for managing the symptoms and side effects of chronic tinnitus. Cognitive Behaviorial Therapy for Tinnitus is the first book to provide comprehensive CBT counseling materials specifically developed for the management of tinnitus. This valuable professional book has two primary purposes: to provide clinical guidelines for audiologists who are offering CBT-based counseling for tinnitus and to provide self-help materials for individuals with tinnitus. In addition, these materials may be of interest to researchers developing evidence-based therapies for tinnitus. The book is structured into three sections. Section A provides background information about the theoretical aspects of CBT and some practical tips on how to use this book. Section B provides the CBT counseling, or self-help materials, which can be used by both audiologists and those with tinnitus. Finally, Section C provides some supplementary materials for clinicians that can aid monitoring and engagement of individuals experiencing tinnitus during the course of intervention. Key Features: * The CBT materials contained in this text have been tested in numerous clinical trials across the globe (Australia, Germany, Sweden, United Kingdom, and the United States) both as self-help book chapters and self-help materials delivered via the Internet. * The counseling materials are presented at minimum reading grade level (U.S. 6th grade level) to maximize reader engagement. * The authors of this book have extensive experience in the management of tinnitus, offering useful insights for clinicians and those with tinnitus. * Includes expert advice videos for each chapter to facilitate its adoption to clinical practice.