New Trends In Biomarkers And Diseases An Overview
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New Trends In Biomarkers And Diseases An Overview
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Author : Juan Antonio Vílchez
language : en
Publisher: Bentham Science Publishers
Release Date : 2017-09-29
New Trends In Biomarkers And Diseases An Overview written by Juan Antonio Vílchez and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-29 with Medical categories.
Biomarkers are any measurable biochemical characteristics of an organism that reflect a particular physiological state. Biomarkers can take many different forms including particular proteins or peptides, antibodies, cell types, metabolites, hormones, enzyme levels, compounds related to genomics, etc. A biomarker can also be a substance introduced into a patient to assess the internal organ systems role. In medicine, biomarkers considered as compounds isolated from serum, urine, or other fluids, can be used as an indicator of the presence or severity of a particular disease state. The use of biomarkers is becoming a fundamental practice in medicine, Biomarker research involves a significantly greater scope of laboratory medicine. This monograph presents information on several types of biomarkers for general pathologies (preeclampsia, metabolic syndrome, iron metabolism, bone disease, liver function, renal function), cardiovascular pathology (including atrial fibrillation, peripheral artery disease, thrombotic disorders) and sepsis. Additional information on endocrine and salivary biomarkers is also presented. New Trends in Biomarkers and Diseases: An Overview is an ideal reference for medical students, pathology trainees and clinical researchers seeking information on biomarkers in medicine.
New Trends In Biomarkers And Disease Research
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Author : María Dolores Albaladejo-Otón Juan Antonio Vílchez
language : en
Publisher:
Release Date : 2017-09-29
New Trends In Biomarkers And Disease Research written by María Dolores Albaladejo-Otón Juan Antonio Vílchez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-29 with categories.
Biomarkers are any measurable biochemical characteristics of an organism that reflect a particular physiological state. Biomarkers can take many different forms including particular proteins or peptides, antibodies, cell types, metabolites, hormones, enzyme levels, compounds related to genomics, etc. A biomarker can also be a substance introduced into a patient to assess the internal organ systems role.In medicine, biomarkers considered as compounds isolated from serum, urine, or other fluids, can be used as an indicator of the presence or severity of a particular disease state. The use of biomarkers is becoming a fundamental practice in medicine, Biomarker research involves a significantly greater scope of laboratory medicine.This monograph presents information on several types of biomarkers for general pathologies (preeclampsia, metabolic syndrome, iron metabolism, bone disease, liver function, renal function), cardiovascular pathology (including atrial fibrillation, peripheral artery disease, thrombotic disorders) and sepsis. Additional information on endocrine and salivary biomarkers is also presented.New Trends in Biomarkers and Diseases: An Overview is an ideal reference for medical students, pathology trainees and clinical researchers seeking information on biomarkers in medicine.
Trends In Biomarkers For Neurodegenerative Diseases Current Research And Future Perspectives
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Author : Suman Dutta
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-23
Trends In Biomarkers For Neurodegenerative Diseases Current Research And Future Perspectives written by Suman Dutta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-23 with Science categories.
The Detection Of Biomarkers
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Author : Sibel A. Ozkan
language : en
Publisher: Academic Press
Release Date : 2021-12-05
The Detection Of Biomarkers written by Sibel A. Ozkan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-05 with Medical categories.
Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection. Locates biomarker detection in its research context, setting out present and future prospects Allows clinical researchers to compare various biomarker assays systematically Presents new methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical Gives innovative biomarker assays that are viable alternatives to current complex methods Helps clinical researchers who need reliable, precise and accurate biomarker detection methods
Biomarkers In Bone Disease
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Author : Victor R. Preedy
language : en
Publisher: Springer
Release Date : 2017-07-14
Biomarkers In Bone Disease written by Victor R. Preedy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-14 with Medical categories.
In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics, and so on. The chapters are written by national or international experts and specialists.
Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2010-06-25
Evaluation Of Biomarkers And Surrogate Endpoints In Chronic Disease written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-25 with Medical categories.
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.
Biosocial Surveys
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2008-01-06
Biosocial Surveys written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-06 with Social Science categories.
Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.
The Handbook Of Biomarkers
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Author : Kewal K. Jain
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-02-06
The Handbook Of Biomarkers written by Kewal K. Jain and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-06 with Medical categories.
Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.
Information Resources In Toxicology Volume 1 Background Resources And Tools
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Author : Steve Gilbert
language : en
Publisher: Academic Press
Release Date : 2020-05-16
Information Resources In Toxicology Volume 1 Background Resources And Tools written by Steve Gilbert and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-16 with Medical categories.
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals Explores recent internet trends, web-based databases, and software tools in a section on the online environment Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field
Biomarkers In Drug Development
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Author : Michael R. Bleavins
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20
Biomarkers In Drug Development written by Michael R. Bleavins and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Medical categories.
Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers have emerged as a valuable tool. This book synthesizes and reviews the latest efforts to identify, develop, and integrate biomarkers as a key strategy in translational medicine and the drug development process. Filled with case studies, the book demonstrates how biomarkers can improve drug development timelines, lower costs, facilitate better compound selection, reduce late-stage attrition, and open the door to personalized medicine. Biomarkers in Drug Development is divided into eight parts: Part One offers an overview of biomarkers and their role in drug development. Part Two highlights important technologies to help researchers identify new biomarkers. Part Three examines the characterization and validation process for both drugs and diagnostics, and provides practical advice on appropriate statistical methods to ensure that biomarkers fulfill their intended purpose. Parts Four through Six examine the application of biomarkers in discovery, preclinical safety assessment, clinical trials, and translational medicine. Part Seven focuses on lessons learned and the practical aspects of implementing biomarkers in drug development programs. Part Eight explores future trends and issues, including data integration, personalized medicine, and ethical concerns. Each of the thirty-eight chapters was contributed by one or more leading experts, including scientists from biotechnology and pharmaceutical firms, academia, and the U.S. Food and Drug Administration. Their contributions offer pharmaceutical and clinical researchers the most up-to-date understanding of the strategies used for and applications of biomarkers in drug development.