New Trends In Synthetic Medicinal Chemistry Volume 7
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New Trends In Synthetic Medicinal Chemistry Volume 7
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Author : F. Gualtieri
language : en
Publisher: Wiley-VCH
Release Date : 2000-03-22
New Trends In Synthetic Medicinal Chemistry Volume 7 written by F. Gualtieri and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-03-22 with Medical categories.
The long-awaited volume on synthetic chemistry in the series "Methods and Principles in Medicinal Chemistry" is now available. In the pharmaceutical industry, computational methods play a major role in the discovery and development of new drugs. Yet, the SYNTHESIS of these compounds still remains the most crucial topic in drug design. Written by an internationally renowned team of authors and editors from academia and industry, this volume describes all recent developments in organic synthetic methodology which are essential for pharmaceutical research. The most modern synthetic developments of pharmacologically interesting compounds (carbohydrates and nucleotides) as well as important synthetic methods such as combinatorial chemistry, solid-phase reactions, bioassisted organic synthesis and asymmetric synthesis are critically discussed. Special emphasis is given to a hands-on practical approach which enables researchers to apply the featured methods immediately to their specific problems. Also, the detailed presentation of the topic and the selection of references will be of help to any researcher working in the laboratory.
New Developments In Medicinal Chemistry
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Author : Carlton Anthony Taft
language : en
Publisher: Bentham Science Publishers
Release Date : 2010-12-30
New Developments In Medicinal Chemistry written by Carlton Anthony Taft and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-30 with Medical categories.
"This book is recommended for readers who are interested in or work with current theoretical and experimental research in medicinal chemistry, with an emphasis on computer aided-drug design and organic synthesis for therapeutic purposes. This book encompas"
The Organic Chemistry Of Drug Synthesis Volume 7
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Author : Daniel Lednicer
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-14
The Organic Chemistry Of Drug Synthesis Volume 7 written by Daniel Lednicer and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-14 with Science categories.
The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
The Organic Chemistry Of Drug Synthesis
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Author : Daniel Lednicer
language : en
Publisher: Wiley-Interscience
Release Date : 1996-05-09
The Organic Chemistry Of Drug Synthesis written by Daniel Lednicer and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-09 with Science categories.
The classic reference on the synthesis of medicinal agents --now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6.Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
Synthetic Methods In Drug Discovery
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Author : David C. Blakemore
language : en
Publisher: Royal Society of Chemistry
Release Date : 2016
Synthetic Methods In Drug Discovery written by David C. Blakemore and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Drug development categories.
The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. Similarly, which methodologies are used to progress potential drug candidates from leads through the development process? What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules. Synthetic Methods in Drug Discovery Volume 1 focuses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging areas such as decarboxylative coupling, and the uses of iron and nickel in coupling reactions are also covered. This book provides both academic and industrial perspectives on some key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.
Recent Trends In Carbohydrate Chemistry
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Author : Amélia Pilar Rauter
language : en
Publisher: Elsevier
Release Date : 2020-05-13
Recent Trends In Carbohydrate Chemistry written by Amélia Pilar Rauter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-13 with Science categories.
Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry Demonstrates the importance of carbohydrate chemistry as green and sustainable chemistry Details monosaccharide syntheses and transformations toward biologically active small molecular entities Provides the most recent findings on polysaccharide synthesis and bioapplications
Drug Design
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Author : E. J. Ariëns
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Drug Design written by E. J. Ariëns and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones. The book discusses the design of artificial blood substitutes and auxin-type herbicides; the use of insect pheromones as a basis for the development of more effective selective pest control agents; and the development and application of new steric substituent parameters in drug design. The text also describes the use of computer technology in drug design. Pharmacologists, chemists, biochemists, and people involved in drug design and manufacture will find the book invaluable.
New Tide Of Natural Product Chemistry
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Author : Hayato Ishikawa
language : en
Publisher: Springer
Release Date : 2023-06-30
New Tide Of Natural Product Chemistry written by Hayato Ishikawa and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-30 with Science categories.
This book highlights recent research and advances in natural product chemistry written by promising young researchers in this field who have played a central role for recent innovative advancements. The book consists of seventeen chapters covering novel bioactive natural products, uncovering life phenomena with natural products, biosynthesis of natural products, total synthesis of complex natural products by innovative strategies, and drug discovery using natural products. Each chapter begins with a brief and easy-to-understand introduction, then presents the cutting-edge research in each individual specialty. This book is not only a practical and essential reference resource for natural product chemists, medicinal chemists, synthetic organic chemists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries, but is also a useful guide to understanding new and emerging trends in this field.
Small Molecule Medicinal Chemistry
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Author : Werngard Czechtizky
language : en
Publisher: John Wiley & Sons
Release Date : 2015-11-02
Small Molecule Medicinal Chemistry written by Werngard Czechtizky and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-02 with Science categories.
Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug discovery programs with respect to quality and costs. • Focuses on small molecules and their critical role in medicinal chemistry, reviewing chemical and economic advantages, challenges, and trends in the field from industry perspectives • Discusses novel approaches and key topics, like screening collection enhancement, risk sharing, HTS triage, new lead finding approaches, diversity-oriented synthesis, peptidomimetics, natural products, and high throughput medicinal chemistry approaches • Explains how to reduce design-make-test cycle times by integrating medicinal chemistry, physical chemistry, and ADME profiling techniques • Includes descriptive case studies, examples, and applications to illustrate new technologies and provide step-by-step explanations to enable them in a laboratory setting
Proceedings Of 6th World Congress On Medicinal Chemistry And Drug Design 2017
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Author : ConferenceSeries
language : en
Publisher: ConferenceSeries
Release Date : 2017-06-01
Proceedings Of 6th World Congress On Medicinal Chemistry And Drug Design 2017 written by ConferenceSeries and has been published by ConferenceSeries this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-01 with Medical categories.
June 07-08, 2017 Milan,. Italy Key Topics : Medicinal Chemistry, Synthetic Organic Chemistry, Drug Design and Drug Development, CADD (Computer Aided Drug Design), Bioorganic and Medicinal Chemistry, Pharmacology and toxicology, BioInorganic Chemistry, Organometallic Chemistry, Radiopharmaceuticals, Chemical Biology, Anticancer agents in Medicinal Chemistry, Pharmaceutical Industry, Clinical Pharmacology, Pharmaceutical Sciences, Bioisostere, Analytical Chemistry, Nanomedicine, Stereochemistry, Pharmacovigilance,