Next Generation Sequencing Technologies And Challenges In Sequence Assembly

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Next Generation Sequencing Technologies And Challenges In Sequence Assembly
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Author : Sara El-Metwally
language : en
Publisher: Springer
Release Date : 2014-04-19
Next Generation Sequencing Technologies And Challenges In Sequence Assembly written by Sara El-Metwally and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-19 with Science categories.
The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.
Next Generation Sequencing Technologies And Challenges In Sequence Assembly
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Author : Sara El-Metwally
language : en
Publisher: Springer Science & Business
Release Date : 2014-04-19
Next Generation Sequencing Technologies And Challenges In Sequence Assembly written by Sara El-Metwally and has been published by Springer Science & Business this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-19 with Science categories.
The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.
Next Generation Sequencing And Sequence Assembly
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Author : Ali Masoudi-Nejad
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-09
Next Generation Sequencing And Sequence Assembly written by Ali Masoudi-Nejad and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-09 with Medical categories.
The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about sequencing and assembly methods together, helps both biologists and computer scientists to get a clear idea about the field. Chapters will include information about new sequencing technologies such as ChIp-seq, ChIp-chip, and De Novo sequence assembly.
Next Generation Sequencing
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Author : Jerzy Kulski
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-01-14
Next Generation Sequencing written by Jerzy Kulski and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-14 with Medical categories.
Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences.
Next Generation Sequencing Technologies And Challenges In Sequence Assembly
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Author : M. Sc Sara El-Metwally
language : en
Publisher:
Release Date : 2014-05-31
Next Generation Sequencing Technologies And Challenges In Sequence Assembly written by M. Sc Sara El-Metwally and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-31 with categories.
Plant Life Under Changing Environment
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Author : Durgesh Kumar Tripathi
language : en
Publisher: Academic Press
Release Date : 2020-04-10
Plant Life Under Changing Environment written by Durgesh Kumar Tripathi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-10 with Science categories.
Plant Life under Changing Environment: Responses and Management presents the latest insights, reflecting the significant progress that has been made in understanding plant responses to various changing environmental impacts, as well as strategies for alleviating their adverse effects, including abiotic stresses. Growing from a focus on plants and their ability to respond, adapt, and survive, Plant Life under Changing Environment: Responses and Management addresses options for mitigating those responses to ensure maximum health and growth. Researchers and advanced students in environmental sciences, plant ecophysiology, biochemistry, molecular biology, nano-pollution climate change, and soil pollution will find this an important foundational resource. - Covers both responses and adaptation of plants to altered environmental states - Illustrates the current impact of climate change on plant productivity, along with mitigation strategies - Includes transcriptomic, proteomic, metabolomic and ionomic approaches
Plant Microbe Interactions
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Author : Jagajjit Sahu
language : en
Publisher: CRC Press
Release Date : 2022-07-11
Plant Microbe Interactions written by Jagajjit Sahu and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-11 with Medical categories.
A constant research effort to understand plant-microbe interactions makes it indispensable to keep abreast of the latest research developments. Researchers from a range of disciplines have used multiple approaches to infer this field. With the advent of next-generation techniques, both molecular and computational, the field has entered a new phase. These approaches often result in massive information, which is sometimes tangled and in need of further analysis. These types of analyses also require cutting-edge data analytics as well as efficient statistical models. Plant-Microbe Interactions: Harnessing Next-Generation Molecular Technologies for Sustainable Agriculture provides a comprehensive picture of the modern-day analytics and approaches being used to provide insights into the interactions between plant and microbe. A wide range of technologies are explored along with practical guides toward these techniques. A detailed understanding of omics data in various areas could be obtained from this compilation. Key Features: • Crosstalk between plant and microbe • Overview of advanced molecular techniques used to study plant-microbe interaction • Practical guide to technologies such as NGS • Omics data analysis used to study plant-microbe interaction • Role of soil metagenomics • Advanced technologies such as nanotechnology and CRISPR serving to study plant-microbe interaction This book will serve as a great reference to various next-generation techniques in the field of plant-microbe interaction, thereby helping to better understand the mechanism. This will also help budding researchers to shape their research in similar areas.
Clinical Applications For Next Generation Sequencing
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Author : Urszula Demkow
language : en
Publisher: Academic Press
Release Date : 2015-09-10
Clinical Applications For Next Generation Sequencing written by Urszula Demkow and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-10 with Science categories.
Clinical Applications for Next Generation Sequencing provides readers with an outstanding postgraduate resource to learn about the translational use of NGS in clinical environments. Rooted in both medical genetics and clinical medicine, the book fills the gap between state-of-the-art technology and evidence-based practice, providing an educational opportunity for users to advance patient care by transferring NGS to the needs of real-world patients. The book builds an interface between genetic laboratory staff and clinical health workers to not only improve communication, but also strengthen cooperation. Users will find valuable tactics they can use to build a systematic framework for understanding the role of NGS testing in both common and rare diseases and conditions, from prenatal care, like chromosomal abnormalities, up to advanced age problems like dementia. - Fills the gap between state-of-the-art technology and evidence-based practice - Provides an educational opportunity which advances patient care through the transfer of NGS to real-world patient assessment - Promotes a practical tool that clinicians can apply directly to patient care - Includes a systematic framework for understanding the role of NGS testing in many common and rare diseases - Presents evidence regarding the important role of NGS in current diagnostic strategies
Genetics And Genomics Of Pineapple
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Author : Ray Ming
language : en
Publisher: Springer
Release Date : 2018-11-27
Genetics And Genomics Of Pineapple written by Ray Ming and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-27 with Science categories.
This book is the first comprehensive volume on the genetics and genomics of pineapple and provides an overview of the current state of pineapple research. Pineapple [Ananas comosus (L.) Merr.] is the second most important tropical fruit after banana in term of international trade. Its features are advantageous for genomic research: it has a small genome of 527 Mb which is diploid and vegetatively propagated; it is monocot, closely related to the grass family that includes major cereal crops, wheat, rice, corn, sorghum, and millet; and it serves as an out group for genetic and genomic research in grasses. In addition to exploring the evolution and improvement of pineapple, this work examines the pineapple genome with respect to genome structure and organization, comparative analyses with other angiosperm genomes, transcription factors, disease resistance, and circadian clock regulation of CAM related genes. With chapters covering botanical, genetic, genomic, and applied aspects of pineapple, this text also encourages the application of genomic technologies and suggests future prospects.
Genomic Proteomics And Biotechnology
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Author : RC Sobti
language : en
Publisher: CRC Press
Release Date : 2022-12-29
Genomic Proteomics And Biotechnology written by RC Sobti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-29 with Medical categories.
High-throughput molecular technologies ("omics") can help to decipher the contributions of different physiological systems and identify candidate molecules that are representative of different physiological pathways thereby allowing the discovery of biomarkers. Notably, the omics technologies along with and computational methods, bioprospecting, and artificial intelligence will continue to lead to better understanding of biological mechanisms that are responsible for physical attributes, or phenotypes. Research breakthroughs obtained through these technologies can be used to enhance productivity of food animals, meet the increasing demand for animal-sourced foods, enhance high-quality nutrient availability, ensure nutrient safety, mitigate the effects of climate variability, and result in new technologies that provide continued improvement in food security worldwide. Such breakthroughs are an urgent necessity because over the past 50 years, there has been an unprecedented increase in the world’s population, which will reach ten billion by the year 2050. Innovative and technological advancements that enhance all aspects of food production will arise from basic, fundamental research. Besides food, animal by-products have found many applications in the fields of pharmaceuticals, cosmetics, and household and industrial products. Hence, the need to ameliorate the productivity, reproductivity, growth performance, and disease resistance in animals has created a worldwide interest in gaining a deeper understanding of animal biology, biotechnology and genomics, and proteomics. The present volume thoroughly discusses the omics studies in domestic and non-domestic animals and their role in mitigation of various challenges ahead. The volume thus focuses on i. Omics (genomics, proteomics, transcriptomics, metabolonomics) technologies in identifying, characterizing biodiversity ii. Role of molecular techniques for improvement of domestic and non-domestic organisms iii. Animal and alternative model systems (using stem cells, tissue engineering, cell free systems, 3D platforms etc.) for studying life phenomena iv. Genetically modified organisms as factories for the products