Nmr Applications In Biopolymers


Nmr Applications In Biopolymers
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Nmr Applications In Biopolymers


Nmr Applications In Biopolymers
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Author : John W. Finley
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Nmr Applications In Biopolymers written by John W. Finley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Elucidating the structures of biopolymers as they exist in nature has long been a goal of biochemists and biologists. Understanding how these substances interact with themselves, other solutes, and solvents can provide useful insights into many areas of biochemistry, agriculture, food science and medicine. Knowledge of the structure of a protein or complex carbohydrate in its native form provides guidelines for the chemical or genetic modifications often desired to optimize these compounds to specific needs and applications. For example, in the pharmaceutical industry, structure-function relationships involving biopolymers are studied rou tinely as a means to design new drugs and improve their efficacies. The tools to conduct structure investigations of biopolymers at the molecular level are limited in number. Historically X-ray crystallography has been the most attractive method to conduct studies of this type. How ever, X-ray methods can only be applied to highly ordered, crystalline materials, thus obviating studies of solution dynamics that are often critical to attaining a global understanding of biopolymer behavior. In recent years, nuclear magnetic resonance (NMR) spectroscopy has evolved to become a powerful tool to probe the structures of biopolymers in solution and in the solid state. NMR provides a means to study the dynamics of polymers in solution, and to examine the effects of solute, solvent and' other factors~n polymer behavior. With the development of 2D and 3D forms of NMR spectroscopy, it is now possible to assess the solution conforma tions of small proteins, oligonucleotides and oligosaccharides.



Solid State Nmr Spectroscopy For Biopolymers


Solid State Nmr Spectroscopy For Biopolymers
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Author : Hazime Saitô
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-08-05

Solid State Nmr Spectroscopy For Biopolymers written by Hazime Saitô and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-08-05 with Science categories.


‘‘Biopolymers’’ are polymeric materials of biological origin, including globular, membrane, and fibrous proteins, polypeptides, nucleic acids, po- saccharides, lipids, etc. and their assembly, although preference to respe- ive subjects may be different among readers who are more interested in their biological significance or industrial and/or medical applications. Nevert- less, characterizing or revealing their secondary structure and dynamics may be an equally very important and useful issue for both kinds of readers. Special interest in revealing the 3D structure of globular proteins, nucleic acids, and peptides was aroused in relation to the currently active Structural Biology. X-ray crystallography and multidimensional solution NMR sp- troscopy have proved to be the standard and indispensable means for this purpose. There remain, however, several limitations to this end, if one intends to expand its scope further. This is because these approaches are not always straightforward to characterize fibrous or membrane proteins owing to extreme difficulty in crystallization in the former, and insufficient spectral resolution due to sparing solubility or increased effective molecular mass in the presence of surrounding lipid bilayers in the latter.



Solid State Nmr Studies Of Biopolymers


Solid State Nmr Studies Of Biopolymers
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Author : Anne E. McDermott
language : en
Publisher: John Wiley & Sons
Release Date : 2012-12-19

Solid State Nmr Studies Of Biopolymers written by Anne E. McDermott and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-19 with Science categories.


The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Practical examples of biochemical applications are included, along with a detailed discussion of the many aspects of sample preparation and handling that make spectroscopy on solid proteins successful. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here



Nmr Methods For Characterization Of Synthetic And Natural Polymers


Nmr Methods For Characterization Of Synthetic And Natural Polymers
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Author : Rongchun Zhang
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-08-02

Nmr Methods For Characterization Of Synthetic And Natural Polymers written by Rongchun Zhang and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-02 with Science categories.


Since the introduction of FT-NMR spectroscopy around five decades ago, NMR has achieved significant advances in hardware and methodologies, accompanied with the enhancement of spectral resolution and signal sensitivity. Rapid developments in the polymers field mean that accurate and quantitative characterization of polymer structures and dynamics is the keystone for precisely regulating and controlling the physical and chemical properties of the polymer. This book specifically focuses on NMR investigation of complex polymers for the polymer community as well as NMR spectroscopists, and will push the development of both fields. It covers the latest advances, for example high field DNP and ultrafast MAS methodologies, and show how these novel NMR methods characterize various synthetic and natural polymers.



Handbook Of Biopolymer Based Materials


Handbook Of Biopolymer Based Materials
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Author : Sabu Thomas
language : en
Publisher: John Wiley & Sons
Release Date : 2013-04-16

Handbook Of Biopolymer Based Materials written by Sabu Thomas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-16 with Technology & Engineering categories.


This first systematic scientific reference in the area of micro- and nanostructured biopolymer systems discusses in two volumes the morphology, structure, dynamics, properties and applications of all important biopolymers, as well as their blends, composites, interpenetrating networks and gels. Selected leading researchers from industry, academia, government and private research institutions around the globe comprehensively review recent accomplishments in the field. They examine the current state of the art, new challenges, and opportunities, discussing all the synthetic routes to the generation of both micro- and nano-morphologies, as well as the synthesis, characterization and application of porous biopolymers. An outstanding resource for anyone involved in the fi eld of eco-friendly biomaterials for advanced technologies.



Models Of Biopolymers By Ring Opening Polymerization


Models Of Biopolymers By Ring Opening Polymerization
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Author : Stanislaw Penczek
language : en
Publisher: CRC Press
Release Date : 2018-01-18

Models Of Biopolymers By Ring Opening Polymerization written by Stanislaw Penczek and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Science categories.


There are a number of methods used to synthetically prepare biopolymers, their models, and bioanalogous polymers. This work approaches the syntheses of the three major groups of biopolymers existing in nature - polypeptides, polysaccharides, and nucleic and teichoic acids - by ring-opening polymerization. Until now, this method has never been reviewed uniformly for these three groups. The majority of models prepared by ring-opening polymerization can not reach the complexity of the actual biological molecules. However, a better understanding of these biopolymers will aid in the use of such molecules in several fields of application in research and other high technologies, where they mimic functions of related biopolymers in living organisms.



Nmr Of Polymers


Nmr Of Polymers
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Author : Frank A. Bovey
language : en
Publisher: Academic Press
Release Date : 1996-11-19

Nmr Of Polymers written by Frank A. Bovey and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-11-19 with Science categories.


NMR has made important contributions to our understanding of structure–property relationships in polymers. This book provides an up-to-date and comprehensive overview of the fundamentals of NMR, with applications of multidimensional NMR and the new solution and solid-state methods in polymer science. NMR of Polymers is written by leading authorities for graduate students and professionals in academia and industry. Provides comprehensive overview of NMR in Polymer Science Covers multidimensional NMR Includes new solution and solid state methods Addresses chain conformation and dynamics



Computational Aspects Of The Study Of Biological Macromolecules By Nuclear Magnetic Resonance Spectroscopy


Computational Aspects Of The Study Of Biological Macromolecules By Nuclear Magnetic Resonance Spectroscopy
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Author : Jeffrey C. Hoch
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-21

Computational Aspects Of The Study Of Biological Macromolecules By Nuclear Magnetic Resonance Spectroscopy written by Jeffrey C. Hoch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.


This volume is the scientific chronicle of the NATO Advanced Research Workshop on Computational Aspects of the Study of Biological Macro molecules by Nuclear Magnetic Resonance Spectroscopy, which was held June 3-8, 1990 at Il Ciocco, near Barga, Italy. The use of computers in the study of biological macromolecules by NMR spectroscopy is ubiquitous. The applications are diverse, including data col lection, reduction, and analysis. Furthermore, their use is rapidly evolv ing, driven by the development of new experimental methods in NMR and molecular biology and by phenomenal increases in computational perfor mance available at reasonable cost. Computers no longer merely facilitate, but are now absolutely essential in the study of biological macromolecules by NMR, due to the size and complexity of the data sets that are obtained from modern experiments. The Workshop, and this proceedings volume, provide a snapshot of the uses of computers in the NMR of biomolecules. While by no means exhaustive, the picture that emerges illustrates both the· importance and the diversity of their application.



Biopolymers For Medical Applications


Biopolymers For Medical Applications
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Author : Juan M. Ruso
language : en
Publisher: CRC Press
Release Date : 2017-02-17

Biopolymers For Medical Applications written by Juan M. Ruso and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-17 with Medical categories.


This book presents an experimental and computational account of the applications of biopolymers in the field of medicine. Biopolymers are macromolecules produced by living systems, such as proteins, polypeptides, nucleic acids, and polysaccharides. Their advantages over polymers produced using synthetic chemistry include: diversity, abundance, relatively low cost, and sustainability. This book explains techniques for the production of different biodevices, such as scaffolds, hydrogels, functional nanoparticles, microcapsules, and nanocapsules. Furthermore, developments in nanodrug delivery, gene therapy, and tissue engineering are described.



Advances In Physicochemical Properties Of Biopolymers Part 1


Advances In Physicochemical Properties Of Biopolymers Part 1
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Author : Martin Masuelli
language : en
Publisher: Bentham Science Publishers
Release Date : 2017-07-05

Advances In Physicochemical Properties Of Biopolymers Part 1 written by Martin Masuelli and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-05 with Technology & Engineering categories.


The last two decades have seen a number of significant advances in the methodology for evaluating the molecular weight distributions of polydispersed macromolecular systems in solution at the molecular level. This reference presents reviews on the progress in different analytical and characterization methods of biopolymers. Readers will find useful information about combinations of complex biopolymer analysis such as chromatographic or membrane based fractionation procedures combined with multiple detectors on line (multi-angle laser light scattering or MALLS). Key topics include: • refractive index, UV-Vis absorbance and intrinsic viscosity detection systems, • advances in SEC-MALLS (size exclusion chromatography coupled to multi-angle laser light scattering) and FFF-MALLS (field flow fractionation coupled on line to MALLS), • HPSEC-A4F-MALLS, matrix-assisted laser-desorption ionization (MALDI) • electrospray ionization (ESI) mass spectrometry • nuclear magnetic resonance (NMR) spectroscopy This reference is intended for students of applied chemistry and biochemistry who require information about biopolymer analysis and characterization.