Nmr Principles And Applications To Biomedical Research

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Nmr Principles And Applications To Biomedical Research

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Author : Jay W. Pettegrew
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Nmr Principles And Applications To Biomedical Research written by Jay W. Pettegrew and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Technology & Engineering categories.

Nuclear magnetic resonance (NMR) is having an enormous liTIpact on biomedical research both at the basic science and clinical levels. In order to appreciate the elegance and power of this technology a historical perspective is in order. In 1924 Pauli suggested that hydrogen nuclei might possess a magnetic IIlOlllent. This was in fact confinned by Rabbi in 1939 who demonstrated that a beam of hydrogen molecules in the presence of a magnetic field could be mutated by radio frequency fields resonating at the Iarmor frequency. 'Ihe first successful NMR experiments in condensed matter were independently conducted in late 1945 by Purcell, Torrey and PoUnd and by Bloch, Hansen and Packard. 'Ihe Purcell group detected proton NMR in solid paraffin and the Bloch group detected proton in liquid water. Bloch and Purcell received the Nobel Prize in physics in 1952 for these observations . Until about 1952, studies of liquids and solids with broad resonance lines dominated the field of NMR. However, the reports of 3 1 P NMR chemical shifts in several corrpounds in 1949 by Khight, of 14 N resonances in several ions by Proctor and Yu in 1950, and of 1 9 F resonances in several corrpounds in 1950 by Dickinson led to the development of high resolution NMR in Itquids. since the molecular motions in liquids result in very narrow lines compared to those in solids, :much smaller chemical shifts could be detected.

Nmr

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Author : Jay W. Pettegrew
language : en
Publisher:
Release Date : 1990-01

Nmr written by Jay W. Pettegrew and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-01 with Imagerie par résonance magnétique categories.

Nmr Spectroscopy And Its Application To Biomedical Research

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Author : S.K. Sarkar
language : en
Publisher: Elsevier
Release Date : 1996-12-04

Nmr Spectroscopy And Its Application To Biomedical Research written by S.K. Sarkar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-12-04 with Science categories.

NMR has become the most diverse spectroscopic tool available to date in biomedical research. It is now routinely used to study biomolecular structure and dynamics particularly as a result of recent developments of a cascade of highly sophisticated multidimensional NMR pulse sequences, and of advances in genetic engineering to produce biomolecules, uniformly or selectively enriched with 13C, 15N and 2H.Features of this book:• Provides an up-to-date treatment of NMR techniques and their application to problems of biomedical interest• Most refined multidimensional pulse sequences including the basic aspects are covered by leading NMR spectroscopists.The book will be useful to NMR spectroscopists, biochemists, and to molecular biologists interested in the use of NMR techniques for solving biological problems.

Nida Research Monograph

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Author :
language : en
Publisher:
Release Date : 1976

Nida Research Monograph written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Drug abuse categories.

National Library Of Medicine Current Catalog

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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1990

National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medicine categories.

Fundamentals Of Protein Nmr Spectroscopy

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Author : Gordon S. Rule
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-10-28

Fundamentals Of Protein Nmr Spectroscopy written by Gordon S. Rule and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-10-28 with Science categories.

NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.

Biological Nmr Spectroscopy

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Author : John L. Markley
language : en
Publisher: Oxford University Press
Release Date : 1997-01-30

Biological Nmr Spectroscopy written by John L. Markley and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-30 with Science categories.

This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.

Human Helminthiasis

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Author : Luis Rodrigo
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-02-15

Human Helminthiasis written by Luis Rodrigo and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-15 with Medical categories.

Human helminthiasis, known as worm infections, is any macroparasitic disease affecting humans, in which a part of the body is invaded by a lot of worms, known as helminths. They are broadly classified into flukes, tapeworms, and roundworms. Soil-transmitted helminthiasis and schistosomiasis are the most important, being included into the neglected tropical diseases. Helminthiasis has been found to result in poor birth outcome, less cognitive development, lower school and work performance, lower socioeconomic development, and poverty. Soil-transmitted helminthiases are responsible for parasitic infections in as much as a quarter of the human population worldwide. This group of infective diseases has been targeted under the joint action of the world's leading pharmaceutical companies and local governments, trying to achieve their eradication.

Cambridge Medical Reviews Neurobiology And Psychiatry Volume 2

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Author : David Dawbarn
language : en
Publisher: Cambridge University Press
Release Date : 1993-11-18

Cambridge Medical Reviews Neurobiology And Psychiatry Volume 2 written by David Dawbarn and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-18 with Medical categories.

This 1993 text served as a regular forum for evaluation and dissemination of information in the neurobiological basis of psychiatric disorder.

Current Catalog

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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1982

Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medicine categories.

First multi-year cumulation covers six years: 1965-70.