Non Covalent Interactions In Proteins
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Non Covalent Interactions In Proteins Second Edition
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Author : Andrey Karshikoff
language : en
Publisher: World Scientific
Release Date : 2021-11-08
Non Covalent Interactions In Proteins Second Edition written by Andrey Karshikoff and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-08 with Science categories.
Although textbooks on the physics of condensed matter consider non-covalent interactions in detail, their application for analysis of protein properties is often poorly presented or omitted. On the other hand, books on biochemistry, molecular modeling or molecular simulation introduce these interactions in the context of the corresponding topic, which sometimes results in superficial explanations of their nature. This book succeeds in uniting comprehensive considerations of non-covalent interactions with the specificity of their application in protein sciences.This second edition includes new chapters on intrinsically disordered proteins, microcalorimetry of proteins, cold denaturation, thermodynamic stability and thermal adaptability of proteins. The ideal aid for students of physics or chemistry, with interests in biology and biophysics, the book can also be useful for students of biology, biochemistry, or biomedicine who want to extend their knowledge of how protein properties are described at the molecular level.
Non Covalent Interactions In Proteins
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Author : Andrey Karshikoff
language : en
Publisher:
Release Date : 2006
Non Covalent Interactions In Proteins written by Andrey Karshikoff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Non Covalent Interactions In Protein
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Author : Andrey Karshikoff
language : en
Publisher:
Release Date : 2006
Non Covalent Interactions In Protein written by Andrey Karshikoff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
Non Covalent Interactions
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Author : Pavel Hobza
language : en
Publisher: Royal Society of Chemistry
Release Date : 2010
Non Covalent Interactions written by Pavel Hobza and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Science categories.
Co-authored by an experimentalist (Klaus M3ller-Dethlefs ) and theoretician (Pavel Hobza), the aim of this book is to provide a general introduction into the science behind non-covalent interactions and molecular complexes using some important experimental and theoretical methods and approaches.
Non Covalent Interactions In Multi Subunit Protein Assemblies
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Author : M. G. McCammon
language : en
Publisher:
Release Date : 2001
Non Covalent Interactions In Multi Subunit Protein Assemblies written by M. G. McCammon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Electrospray ionization mass spectrometry categories.
Substitution Inert Platinum Ii Complexes And Their Non Covalent Interactions With Proteins
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Author : Thomas A. Wells
language : en
Publisher:
Release Date : 2020
Substitution Inert Platinum Ii Complexes And Their Non Covalent Interactions With Proteins written by Thomas A. Wells and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Chemotherapy categories.
Traditional platinum complexes are commonplace in chemotherapeutics. While effective, the toxicity of these complexes and development of resistance are inherent drawbacks that need to be addressed. This work focuses on the development of a new class of platinum (II) complexes designed for non-covalent, electrostatic interactions with proteins relevant to cancer and HIV-1. Chapter two focuses on mono and dinuclear substitution-inert platinum complexes and their selectivity for the N-terminal of the HIV-1 NCp7 protein. Chapters three and four investigate a second phenotype of mononuclear platinum complexes with bis conformations and their interactions with the p53-MDM2 interface. Chapter five provides insight into isoelectronic gold (III) complexes and an aryl-transfer mechanism to NCp7. Chapter six explains the recovery of platinum from laboratory wastes. Overall, the work presented in this dissertation expands on the class of substitution-inert platinum(II) complexes and assesses their viability to interact with specific active-site residues of the HIV-1 NCp7 protein and the p53-MDM2 interface.
Non Covalent Interactions In Multi Subunit Protein Assemblies
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Author : M. G. McCammon
language : en
Publisher:
Release Date : 2001
Non Covalent Interactions In Multi Subunit Protein Assemblies written by M. G. McCammon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Electrospray ionization mass spectrometry categories.
Protein Folding Kinetics
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Author : Bengt Nölting
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-05
Protein Folding Kinetics written by Bengt Nölting and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-05 with Science categories.
First methods book which includes many detailed descriptions Absolutely needed and thus timely for the scientific community Comprises 15% more content and includes the mentioned special features
Studies Of Non Covalent Small Molecule Dna Interactions And Protein Dna Interactions
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Author : Amit Kapur
language : en
Publisher:
Release Date : 2002
Studies Of Non Covalent Small Molecule Dna Interactions And Protein Dna Interactions written by Amit Kapur and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with DNA-protein interactions categories.
Protein Protein Recognition
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Author : Colin Kleanthous
language : en
Publisher: Frontiers in Molecular Biology
Release Date : 2000
Protein Protein Recognition written by Colin Kleanthous and has been published by Frontiers in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Carrier proteins categories.
The purpose of Protein-Protein Recognition is to bring together concepts and systems pertaining to protein-protein interactions in a single unifying volume. In the light of the information from the genome sequencing projects and the increase in structural information it is an opportune time totry to make generalizations about how and why proteins form complexes with each other. The emphasis of the book is on heteromeric complexes (complexes in which each of the components can exist in an unbound state) and will use well-studied model systems to explain the processes of formingcomplexes. After an introductory section on the kinetics, thermodynamics, analysis, and classification of protein-protein interactions, weak, intermediate, and high affinity complexes are dealt with in turn. Weak affinity complexes are represented by electron transfer proteins and integrincomplexes. Anti-lysozyme antibodies, the MHC proteins and their interactions with T-cell receptors, and the protein interactions of eukaryotic signal transduction are the systems used to explain complexes with intermediate affinities. Finally, tight binding complexes are represented by theinteraction of protein inhibitors with serine proteases and by nuclease inhibitor complexes. Throughout the chapters common themes are the technologies which have had the greatest impact, how specificity is determined, how complexes are stabilized, and medical and industrial applications.