Nordic Workshop On New Approach Methodologies Nams
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Nordic Workshop On New Approach Methodologies Nams
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Author : Wojewodzic, Marcin W.
language : en
Publisher: Nordic Council of Ministers
Release Date : 2022-05-20
Nordic Workshop On New Approach Methodologies Nams written by Wojewodzic, Marcin W. and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-20 with Science categories.
Available online: https://pub.norden.org/temanord2022-526/ New Approach Methodologies (NAMs) are an emerging tool in toxicology for performing chemical risk assessment. NAMs reduce animal testing while increasing robustness, throughput and providing a mechanistic understanding of chemical modes-of-actions, in accordance with the Next Generation Risk Assessment principles. The workshop’s objective was to increase risk assessors’ understanding of the data produced by NAMs and their ability to use it for regulatory actions under REACH and CLP. It aimed to highlight the main challenges for NAMs, discuss possible advancements in using NAMs, and increase knowledge and competence within the relevant Nordic authorities. It also served to facilitate discussions about the obstacles to implementing NAMs in regulatory processes, and to identify strategies (including omics approaches) for increasing their use in read-across and grouping processes.
Validation Of Alternative Methods For Toxicity Testing
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Author : Chantra Eskes
language : en
Publisher: Springer
Release Date : 2016-09-26
Validation Of Alternative Methods For Toxicity Testing written by Chantra Eskes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-26 with Medical categories.
This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.
Multiword Expressions
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Author : Manfred Sailer
language : en
Publisher: Language Science Press
Release Date :
Multiword Expressions written by Manfred Sailer and has been published by Language Science Press this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Multiword expressions (MWEs) are a challenge for both the natural language applications and the linguistic theory because they often defy the application of the machinery developed for free combinations where the default is that the meaning of an utterance can be predicted from its structure. There is a rich body of primarily descriptive work on MWEs for many European languages but comparative work is little. The volume brings together MWE experts to explore the benefits of a multilingual perspective on MWEs. The ten contributions in this volume look at MWEs in Bulgarian, English, French, German, Maori, Modern Greek, Romanian, Serbian, and Spanish. They discuss prominent issues in MWE research such as classification of MWEs, their formal grammatical modeling, and the description of individual MWE types from the point of view of different theoretical frameworks, such as Dependency Grammar, Generative Grammar, Head-driven Phrase Structure Grammar, Lexical Functional Grammar, Lexicon Grammar.
Index Of Conference Proceedings
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Author :
language : en
Publisher:
Release Date : 1995
Index Of Conference Proceedings written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Conference proceedings categories.
Arctic Human Development Report
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Author : Joan Nymand Larsen
language : en
Publisher: Nordic Council of Ministers
Release Date : 2015-02-18
Arctic Human Development Report written by Joan Nymand Larsen and has been published by Nordic Council of Ministers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-18 with Arctic peoples categories.
The goals of the second volume of the AHDR – Arctic Human Development Report: Regional Processes and Global Linkages – are to provide an update to the first AHDR (2004) in terms of an assessment of the state of Arctic human development; to highlight the major trends and changes unfolding related to the various issues and thematic areas of human development in the Arctic over the past decade; and, based on this assessment, to identify policy relevant conclusions and key gaps in knowledge, new and emerging Arctic success stories. The production of AHDR-II on the tenth anniversary of the first AHDR makes it possible to move beyond the baseline assessment to make valuable comparisons and contrasts across a decade of persistent and rapid change in the North. It addresses critical issues and emerging challenges in Arctic living conditions, quality of life in the North, global change impacts and adaptation, and Indigenous livelihoods. The assessment contributes to our understanding of the interplay and consequences of physical and social change processes affecting Arctic residents’ quality of life, at both the regional and global scales. It shows that the Arctic is not a homogenous region. Impacts of globalization and environmental change differ within and between regions, between Indigenous and non-Indigenous northerners, between genders and along other axes.
Viet Nam S Development Partners
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Author :
language : en
Publisher:
Release Date : 1999
Viet Nam S Development Partners written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Economic assistance categories.
In Vitro Toxicology Systems
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Author : Anna Bal-Price
language : en
Publisher: Humana
Release Date : 2014-05-01
In Vitro Toxicology Systems written by Anna Bal-Price and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-01 with Medical categories.
In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism, and in vitro in vivo extrapolation. The book also addresses biological processes such as stress response pathways and mechanistic biomarkers and how these can be uncovered and measured using high content approaches. Reliable and authoritative, In Vitro Toxicology Systems will be of benefit not only to students, scientists and regulators working in the field of chemical safety assessment but also to a wider scientific audience.
The Global Innovation Index 2013
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Author : Cornell University
language : en
Publisher: WIPO
Release Date : 2013
The Global Innovation Index 2013 written by Cornell University and has been published by WIPO this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Law categories.
The Global Innovation Index ranks the innovation performance of 142 countries and economies around the world, based on 84 indicators. This edition explores the impact of innovation-oriented policies on economic growth and development. High-income and developing countries alike are seeking innovation-driven growth through different strategies. Some countries are successfully improving their innovation capacity, while others still struggle.
Labour Inspection
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Author : W. Von Richthofen
language : en
Publisher: International Labour Organization
Release Date : 2002
Labour Inspection written by W. Von Richthofen and has been published by International Labour Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Business & Economics categories.
Topics covered include background, evaluation, policy, organization and management for labour inspection, sectoral aspects such as child labour, agriculture, non-commercial service sector, construction industry, labour inspection and hazards prevention.
The Global Innovation Index 2014
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Author : Cornell University
language : en
Publisher: WIPO
Release Date : 2014
The Global Innovation Index 2014 written by Cornell University and has been published by WIPO this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Law categories.
The Global Innovation Index ranks the innovation performance of 143 countries and economies around the world, based on 81 indicators. This edition explores the role of the individuals and teams behind the innovation process. It sheds light on different aspects of human capital required to achieve innovation, including skilled labor; the intersection of human, financial and technological capital; talent retention; and the mobilization of highly educated people.