Novel Concepts In Cardiac Energy Metabolism From Biology To Disease


Novel Concepts In Cardiac Energy Metabolism From Biology To Disease
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Novel Concepts In Cardiac Energy Metabolism From Biology To Disease


Novel Concepts In Cardiac Energy Metabolism From Biology To Disease
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Author : Thomas Pulinilkunnil
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-08

Novel Concepts In Cardiac Energy Metabolism From Biology To Disease written by Thomas Pulinilkunnil and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-08 with categories.


This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



The Scientist S Guide To Cardiac Metabolism


The Scientist S Guide To Cardiac Metabolism
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Author : Michael Schwarzer
language : en
Publisher: Academic Press
Release Date : 2015-11-04

The Scientist S Guide To Cardiac Metabolism written by Michael Schwarzer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-04 with Medical categories.


The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field



Cardiac Energy Metabolism In Health And Disease


Cardiac Energy Metabolism In Health And Disease
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Author : Gary D. Lopaschuk
language : en
Publisher: Springer
Release Date : 2014-08-22

Cardiac Energy Metabolism In Health And Disease written by Gary D. Lopaschuk and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-22 with Science categories.


The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.



Biology Of Cardiovascular And Metabolic Diseases


Biology Of Cardiovascular And Metabolic Diseases
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Author : Chaya Gopalan
language : en
Publisher: Academic Press
Release Date : 2022-01-11

Biology Of Cardiovascular And Metabolic Diseases written by Chaya Gopalan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-11 with Medical categories.


Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions. Focuses succinctly on the physiology and pathophysiology of cardiovascular and metabolic diseases Written in a concise and easy to read manner, allowing readers to quickly understand concepts Highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure



Cellular And Molecular Pathobiology Of Cardiovascular Disease


Cellular And Molecular Pathobiology Of Cardiovascular Disease
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Author : Monte Willis
language : en
Publisher: Academic Press
Release Date : 2013-12-23

Cellular And Molecular Pathobiology Of Cardiovascular Disease written by Monte Willis and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-23 with Medical categories.


Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology



Biophysics Of The Failing Heart


Biophysics Of The Failing Heart
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Author : R. John Solaro
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-08-13

Biophysics Of The Failing Heart written by R. John Solaro and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-13 with Science categories.


Subjects in the monograph “Biophysics of the Failing Heart” include state of the art chapters considering major biophysical mechanisms for why hearts responding to acquired or inherited stressors enter into maladaptive processes eventually leading to an inability of the heart to respond efficiently to hemodynamic loads especially during exercise. The chapters describe biophysical techniques that have been applied to determine the triggers for the heart failure process as well as the mechanisms for sustaining the disorders. These techniques include measurements of active and passive mechanical properties and hemodynamics at levels of organization ranging from molecules to hearts beating in situ. Biophysical concepts and approaches are also applied to determination of signaling and signal transduction, energetics, ionic currents, transport processes, electro-chemical and chemo-mechanical coupling. By its emphasis on biophysical aspects of a prevalent clinical condition, the monograph is unique in its perspective and focus. The breadth of information in the chapters all in one place will be of value to clinicians and researchers at all levels. Modern research approaches and clinical understanding of heart failure demands integration of multiple aspects of the disorders. In most cases, combinations of clinician scientists and researchers author the chapters. A main benefit of the book is couched in its didactic approach together with its emphasis on how biophysical concepts and techniques aid in diagnosis and development of new therapies.



Concepts Of Biology


Concepts Of Biology
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Author : Samantha Fowler
language : en
Publisher:
Release Date : 2018-01-07

Concepts Of Biology written by Samantha Fowler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-07 with Science categories.


Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.



Foundations Of Systems Biology


Foundations Of Systems Biology
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Author : Hiroaki Kitano
language : en
Publisher: MIT Press (MA)
Release Date : 2001

Foundations Of Systems Biology written by Hiroaki Kitano and has been published by MIT Press (MA) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Computers categories.


An overview of the methodologies and techniques of the emerging field of systems biology.



Exercise Physiology


Exercise Physiology
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Author : William D. McArdle
language : en
Publisher:
Release Date : 1991

Exercise Physiology written by William D. McArdle and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


Abstract: This third edition of the book integrates basic concepts and relevant scientific information to provide the foundation for understanding nutrition, energy transfer, and exercise and training. Designed for both the beginning and advanced student, the subjects covered include energy for physical activity, systems of energy delivery and utilization, enhancement of energy capacity, work performance and environmental stress, body composition, energy balance, and weight control, and the metric system and SI units.



Lipid Signaling And Metabolism


Lipid Signaling And Metabolism
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Author : James M. Ntambi
language : en
Publisher: Academic Press
Release Date : 2020-08-09

Lipid Signaling And Metabolism written by James M. Ntambi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-09 with Science categories.


Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine. Provides a clear, up-to-date understanding of lipid signaling and metabolism and the impact of recent technologies critical to advancing new studies Empowers researchers to examine bioactive lipid signaling and metabolism, supporting translation to clinical care and precision medicine Discusses the role of lipid signaling and metabolism in obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders, among others