Novel Type Dimeric Naphthylisoquinoline Alkaloids From Congolese Ancistrocladus Lianas
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Novel Type Dimeric Naphthylisoquinoline Alkaloids From Congolese Ancistrocladus Lianas
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Author : Blaise Kimbadi Lombe
language : en
Publisher:
Release Date : 2019
Novel Type Dimeric Naphthylisoquinoline Alkaloids From Congolese Ancistrocladus Lianas written by Blaise Kimbadi Lombe and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Ancistrocladus Naphthylisoquinoline Alkaloids
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer Nature
Release Date : 2023-01-01
Ancistrocladus Naphthylisoquinoline Alkaloids written by A. Douglas Kinghorn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Science categories.
This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented.
Isolation And Structural Elucidation Of Novel Anti Infective Naphthylisoquinoline Alkaloids From Ancistrocladus Ealaensis And Phytochemical Analysis Of Two Congolese Medicinal Plants
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Author : Dieudonné Tshitenge Tshitenge
language : en
Publisher:
Release Date : 2019
Isolation And Structural Elucidation Of Novel Anti Infective Naphthylisoquinoline Alkaloids From Ancistrocladus Ealaensis And Phytochemical Analysis Of Two Congolese Medicinal Plants written by Dieudonné Tshitenge Tshitenge and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Novel Plant Natural Product Skeletons
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Author : Yongxian Cheng
language : en
Publisher: Springer Nature
Release Date : 2024-02-02
Novel Plant Natural Product Skeletons written by Yongxian Cheng and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-02 with Science categories.
This book provides an overview of the new plant natural product skeletons discovered from 1999 to 2021. It categorizes these natural products by providing their names, source distributions, structural types, structure characteristics, and bioactivities. A total of 1373 plant products in 99 families are presented, which cover 36 different structure types within the Hypericaceae family of which the majority are alkaloid structures. In addition, it presents the biological profiling in the last 23 years by summarizing the biological activities and potential disadvantages. The new natural products skeleton presented are unprecedented structural scaffolds and could bring new opportunities for biological/pharmaceutical areas and provide new structure templates for synthetic chemists. This book helps readers gain in-depth insight into the past and recent trends of natural products; it also assists those interested in assessing the potential biological function of the natural products.
The Alkaloids
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-05-27
The Alkaloids written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-27 with Science categories.
The Alkaloids: Chemistry and Biology, Volume 91, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Recent Progress in the Chemistry of Naphthylisoquinoline Alkaloids. Provides the latest information on the study of alkaloids Covers alkaloid chemistry, biology, pharmacology, and medical applications Contains more than 80 published volumes in this interesting field of study
African Plant Based Products As A Source Of Potent Drugs To Overcome Cancers And Their Chemoresistance
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-06-25
African Plant Based Products As A Source Of Potent Drugs To Overcome Cancers And Their Chemoresistance written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-25 with Science categories.
African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part Two: Potent Botanicals to Overcome Cancers and their Chemoresistance offers detailed information on the best African medicinal plants that could be useful for the development of efficient herbal drugs, as well as the best phytochemicals that could be explored as potential pharmaceuticals to efficiently overcome cancers and their drug resistance. The book identifies and comments on the best cytotoxic African medicinal plants. The book also provides knowledge on ethnomedicinal uses of the identified plants, their pharmacological potency, and their phytochemistry. An overview of the relationship between cancer and other human diseases healed in the traditional health system with the plants documented is also highlighted. The book appears a unique tool for Scientists to have state-of-the-art of the best cytotoxic plants from the African flora. Provides a unique tool compiling the best of African plants with amazing potential toward various cancer cell lines, including the multidrug-resistant phenotypes Discusses in highlights the geographic distribution of the best cytotoxic African plants Compiles the ethnomedicinal, pharmacological, and phytochemistry information of the best antiproliferative African plants
Natural Products In Chemical Biology
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Author : Natanya Civjan
language : en
Publisher: John Wiley & Sons
Release Date : 2012-07-03
Natural Products In Chemical Biology written by Natanya Civjan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-03 with Science categories.
Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.
Antimalarial Natural Products
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Author : A. Douglas Kinghorn
language : en
Publisher: Springer Nature
Release Date : 2022-01-02
Antimalarial Natural Products written by A. Douglas Kinghorn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-02 with Science categories.
This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine’s biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine’s structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature’s combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.
Ultraviolet Visible Spectrophotometry In Pharmaceutical Analysis
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Author : S. Gorog
language : en
Publisher: CRC Press
Release Date : 2018-01-10
Ultraviolet Visible Spectrophotometry In Pharmaceutical Analysis written by S. Gorog and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-10 with Science categories.
This book provides an overview of the state of the art in pharmaceutical applications of UV-VIS spectroscopy. This book presents the fundamentals for the beginner and, for the expert, discusses both qualitative and quantitative analysis problems. Several chapters focus on the determination of drugs in various matrices, the coupling of chromatographic and spectrophotometric methods, and the problems associated with the use of chemical reactions prior to spectrophotometric measurements. The final chapter provides a survey of the spectrophotometric determination of the main families of drugs, emphasizing the achievements of the last decade.
Nutraceuticals And Natural Product Derivatives
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Author : Mohammad Fahad Ullah
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-06
Nutraceuticals And Natural Product Derivatives written by Mohammad Fahad Ullah and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-06 with Science categories.
Introduces readers to the growing applications of nutraceuticals and other natural product derivatives This comprehensive book presents a prophylactic and therapeutic approach to chronic disease prevention strategy by highlighting the translational potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies. It also shares the experiences of highly reputed experts working in the area of phytomedicine and nutraceutical agents in chemoprevention, to promote the significance of natural products and dietary factors as an elite priority for containing chronic diseases in the human population. Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery starts by examining natural food sources for the control of glycemia and the prevention of diabetic complications. It then looks at the anti-aging effects of sulfur-containing amino acids and nutraceuticals, and the potential of garcinia fruits to combat metabolic syndrome. Other topics covered include honey- and propolis-mediated regulation of protein networks in cancer cells; recent trends in drug discovery against Alzheimer’s disease; the therapeutic potential of metalloherbal nanoceuticals; and much more. Offers an alternative, natural approach to the prevention of chronic diseases Emphasizes the potential of plant-derived dietary and non-dietary factors from epidemiological, laboratory, and clinical studies Features contributions from world-renowned experts in the field of phytomedicine and nutraceutical agents in chemoprevention Includes prevention strategies in normal/risk populations through routine inclusion of specific dietary regimens and as therapeutic strategy for better management through adjuvant interventions with conventional treatment protocols Nutraceuticals and Natural Product Derivatives: Disease Prevention & Drug Discovery will appeal to graduate students and professionals in cell and molecular biology, translational research, pharmacology/drug discovery, medicinal chemistry, and clinical nutrition.