Nuclear Pore Complexes In Genome Organization Function And Maintenance
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Nuclear Pore Complexes In Genome Organization Function And Maintenance
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Author : Maximiliano D’Angelo
language : en
Publisher: Springer
Release Date : 2018-02-02
Nuclear Pore Complexes In Genome Organization Function And Maintenance written by Maximiliano D’Angelo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-02 with Medical categories.
The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical role in the establishment and maintenance of chromatin organization and in the regulation of gene activity. These findings, which oppose the traditional view of NPCs as channels with only one: the facilitation of nucleocytoplasmic molecule exchange, have completely transformed our understanding of these structures. This book describes our current knowledge of the role of NPCs in genome organization and gene expression regulation. It starts by providing an overview of the different compartments and structures of the nucleus and how they contribute to organizing the genome, then moves to examine the direct roles of NPCs and their components in gene expression regulation in different organisms, and ends by describing the function of nuclear pores in the infection and genome integration of HIV, in DNA repair and telomere maintenance, and in the regulation of chromosome segregation and mitosis. This book provides an intellectual backdrop for anyone interested in understanding how the gatekeepers of the nucleus contribute to safeguarding the integrity and function of the eukaryotic genome.
Biochemistry And Molecular Biology Compendium
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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2019-11-11
Biochemistry And Molecular Biology Compendium written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Medical categories.
This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers
Spatial Genome Organization
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Author : Karim Mekhail
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-23
Spatial Genome Organization written by Karim Mekhail and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-23 with Science categories.
Nucleocytoplasmic Transport
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Author : Reiner Peters
language : en
Publisher:
Release Date : 1986-11-01
Nucleocytoplasmic Transport written by Reiner Peters and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-11-01 with categories.
Indian Forest Service Exam Zoology Previous Year Paper 2019 To 2023 With Answer By Expert Faculty
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Author :
language : en
Publisher: DIWAKAR EDUCATION HUB
Release Date : 2024-07-14
Indian Forest Service Exam Zoology Previous Year Paper 2019 To 2023 With Answer By Expert Faculty written by and has been published by DIWAKAR EDUCATION HUB this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-14 with Antiques & Collectibles categories.
UPSC Indian Forest Service Exam Zoology Previous year Paper 2019 to 2023 With Answer by Expert Faculty
Epigenetics In Biological Communication
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Author : Guenther Witzany
language : en
Publisher: Springer Nature
Release Date : 2024-06-19
Epigenetics In Biological Communication written by Guenther Witzany and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-19 with Science categories.
Every cell, tissue, organ and organism is competent to use signs to exchange information reaching common coordinations and organisations of both single cell and group behavior. These sign-mediated interactions we term biological communication. The regulatory system that works in development, morphology, cell fate and identity, physiology, genetic instructions, immunity, memory/learning, physical and mental disease depends on epigenetic marks. The communication of cells, persistent viruses and their defectives such as mobile genetic elements and RNA networks ensures both the transport of regulatory instructions and the reprogramming of these instructions. But how are the different states of the epigenome orchestrated? The epigenetic pathways respond to various signaling cues such as DNA methylation, histone variants, histone modifications, chromatin structure, nucleosome remodeling, and epigenetic interactions. Epigenetic signals are responsible for the establishment, maintenance and reversal of transcriptional states that are fundamental for the cell's ability to memorize past events, such as changes in the external environment, socio-sphere or developmental cues. External signals trigger changes in the epigenome, allowing cells to respond dynamically. Internal signals direct activities that are necessary for body maintenance, and repairing damaged tissues and organs. With the emergence of epigenetic memory, organisms can fix historical and context dependent impressive experiences. Evolution from now on learnt to learn. Learning means organisms can avoid reproduction of always the same. This is key to adaptation. However, inheritance of acquired characteristics is only one of the many examples of the explanatory power of epigenetics. Behavioral epigenetics demonstrates the way in which environmental and social experiences produce individual differences in behaviour, cognition, personality, and mental health. This book assembles experts to outline the various motifs of all kinds of epigenetic regulation of cells throughout their lives.
Congenital Heart Diseases The Broken Heart
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Author : Silke Rickert-Sperling
language : en
Publisher: Springer Nature
Release Date : 2024-06-17
Congenital Heart Diseases The Broken Heart written by Silke Rickert-Sperling and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-17 with Medical categories.
This 2nd edition has been extensively updated and provides comprehensive and current insight into congenital heart diseases, from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. The book is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and insights from animal models and pathways. All chapters have been updated and new chapters added on state-of-the-art approaches including stem cells and organoids, cardiac metabolism, single cell transcriptomics and 3D reconstruction of human heart development. The clinical chapters have been extended and include new sections on diagnostic imaging techniques. Taken together, the book, written by and for clinicians and researchers, provides an integrated and up-to-date resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease. Chapter 11 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Is Aberrant Genome Organization A Cause Or Consequence Of Specific Diseases
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Author : Eric C. Schirmer
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-03
Is Aberrant Genome Organization A Cause Or Consequence Of Specific Diseases written by Eric C. Schirmer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-03 with Science categories.
Advances In Medical Biochemistry Genomics Physiology And Pathology
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Author : Raj Bawa
language : en
Publisher: CRC Press
Release Date : 2021-12-22
Advances In Medical Biochemistry Genomics Physiology And Pathology written by Raj Bawa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Medical categories.
The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. While bridging the gap between basic research and clinical medicine, this series provides a thorough understanding of medicine’s potential to address health problems from both the patient’s and the provider’s perspectives in a healthcare setting. The range of topics covered and the expertise of the contributing authors accurately reflect the rapidly evolving areas within medicine—from basic medical sciences to clinical specialties. Each volume is essential reading for physicians, medical students, nurses, fellows, residents, undergraduate and graduate students, educators, policymakers, and biomedical researchers. The multidisciplinary approach of the series makes it a valuable reference resource for the pharmaceutical industry, academia, and governments. However, unlike other series on medicine or medical textbooks, this series focuses on current trends, perspectives, and issues in medicine that are central to healthcare delivery in the 21st century. Volume 1 focuses on the current issues in basic medical sciences, subjects that are fundamental to the practice of medicine. Specifically, it covers medical biochemistry, genomics, physiology, and pathology. These subjects, traditionally taught in the first two years of medical school that precede clinical instruction, provide a core of basic knowledge critical to the success in clinical medicine during rotations, training, and medical practice.
Altered Expression Of Proteins In Cancer Function And Potential Therapeutic Targets
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Author : Varda Shoshan-Barmatz
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-03
Altered Expression Of Proteins In Cancer Function And Potential Therapeutic Targets written by Varda Shoshan-Barmatz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-03 with Medical categories.