Nucleic Acid Architectures For Therapeutics Diagnostics Devices And Materials
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Nucleic Acid Architectures For Therapeutics Diagnostics Devices And Materials
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Author : Kirill A. Afonin
language : en
Publisher: MDPI
Release Date : 2019-08-06
Nucleic Acid Architectures For Therapeutics Diagnostics Devices And Materials written by Kirill A. Afonin and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-06 with Science categories.
This book is a printed edition of the Special Issue Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials that was published in Nanomaterials
Nucleic Acid Architectures For Therapeutics Diagnostics Devices And Materials
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Author : Kirill Afonin
language : en
Publisher:
Release Date : 2019
Nucleic Acid Architectures For Therapeutics Diagnostics Devices And Materials written by Kirill Afonin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.
Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.
Templated Dna Nanotechnology
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Author : Thimmaiah Govindaraju
language : en
Publisher: CRC Press
Release Date : 2019-01-30
Templated Dna Nanotechnology written by Thimmaiah Govindaraju and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-30 with Science categories.
Nucleic acids have structurally evolved over billions of years to effectively store and transfer genetic information. In the 1980s, Nadrian Seeman’s idea of constructing a 3D lattice from DNA led to utilizing DNA as nanomolecular building blocks to create emergent molecular systems and nanomaterial objects. This bottom-up approach to construct nanoscale architectures with DNA marked the beginning of a new field, DNA nanotechnology, contributing significantly to the broad area of nanoscience and nanotechnology. The molecular architectonics of small "designer" molecules and short DNA sequences through complementary binding interaction engenders well-defined functional nanoarchitectures with realistic applications in areas ranging from biology to materials science and is termed "DNA nanoarchitectonics." This book discusses novel approaches adapted by leading researchers from all over the world to create functional nucleic acid molecular systems and nanoarchitectures. Individual chapters contributed by active practitioners provide fundamental and advanced knowledge emanated from their own and others’ work. Each chapter includes numerous illustrations, historical perspectives, case studies and practical examples, critical discussions, and future prospects. This book can serve as a practical handbook or as a textbook for advanced undergraduate- and graduate-level students of nanotechnology and DNA nanotechnology, supramolecular chemistry, and nanoarchitectonics and researchers working on macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in sensors, biosensors, nanoswitches and nanodevices, diagnostics, drug delivery, and therapeutics.
Nucleic Acid Nanotheranostics
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Author : Marco Filice
language : en
Publisher: Elsevier
Release Date : 2019-02-28
Nucleic Acid Nanotheranostics written by Marco Filice and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-28 with Technology & Engineering categories.
Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient's cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book is a valuable guide for materials scientists, physicians, chemists and engineers, but is also ideal for clinicians wishing to expand their knowledge.
Computational Design And Study Of Structural And Dynamic Nucleic Acid Systems
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Author : Fan Hong (Ph. D.)
language : en
Publisher:
Release Date : 2019
Computational Design And Study Of Structural And Dynamic Nucleic Acid Systems written by Fan Hong (Ph. D.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Nucleic acid hybridization categories.
DNA and RNA are generally regarded as one of the central molecules in molecular biology. Recent advancements in the field of DNA/RNA nanotechnology witnessed the success of usage of DNA/RNA as programmable molecules to construct nano-objects with predefined shapes and dynamic molecular machines for various functions. From the perspective of structural design with nucleic acid, there are basically two types of assembly method, DNA tile based assembly and DNA origami based assembly, used to construct infinite-sized crystal structures and finite-sized molecular structures. The assembled structure can be used for arrangement of other molecules or nanoparticles with the resolution of nanometers to create new type of materials. The dynamic nucleic acid machine is based on the DNA strand displacement, which allows two nucleic acid strands to hybridize with each other to displace one or more prehybridized strands in the process. Strand displacement reaction has been implemented to construct a variety of dynamic molecular systems, such as molecular computer, oscillators, in vivo devices for gene expression control. This thesis will focus on the computational design of structural and dynamic nucleic acid systems, particularly for new type of DNA structure design and high precision control of gene expression in vivo. Firstly, a new type of fundamental DNA structural motif, the layered-crossover motif, will be introduced. The layered-crossover allow non-parallel alignment of DNA helices with precisely controlled angle. By using the layered-crossover motif, the scaffold can go through the 3D framework DNA origami structures. The properties of precise angle control of the layered-crossover tiles can also be used to assemble 2D and 3D crystals. One the dynamic control part, a de-novo-designed riboregulator is developed that can recognize single nucleotide variation. The riboregulators can also be used to develop paper-based diagnostic devices.
Nucleic Acid Aptamers For Diagnostics And Therapeutics
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Author : BCC Research
language : en
Publisher:
Release Date : 2012-10
Nucleic Acid Aptamers For Diagnostics And Therapeutics written by BCC Research and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10 with categories.
Synthetic Dna And Rna Programming
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Author : Patrick O’Donoghue
language : en
Publisher: MDPI
Release Date : 2019-11-19
Synthetic Dna And Rna Programming written by Patrick O’Donoghue and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-19 with Science categories.
Dear Colleagues, Synthetic biology is a broad and emerging discipline that capitalizes on recent advances in molecular biology, genetics, protein and RNA engineering and omics technologies. These technologies have transformed our ability to reveal the biology of the cell and the molecular basis of disease. This Special Issue on “Synthetic RNA and DNA Programming” features original research articles and reviews, highlighting novel aspects of basic molecular biology and the molecular mechanisms of disease that were uncovered by the application and development of novel synthetic biology-driven approaches.
Dna And Rna Nanobiotechnologies In Medicine Diagnosis And Treatment Of Diseases
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Author : Volker A. Erdmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-20
Dna And Rna Nanobiotechnologies In Medicine Diagnosis And Treatment Of Diseases written by Volker A. Erdmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-20 with Science categories.
This book will provide latest insights in the functional potentials of ribonucleic acids in medine and the use of Spiegelmer and Spiegelzyme systems. It will also deal with a new type of delivery systems for cellular targeting.
Templated Dna Nanotechnology
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Author : Thimmaiah Govindaraju
language : en
Publisher: CRC Press
Release Date : 2019-01-30
Templated Dna Nanotechnology written by Thimmaiah Govindaraju and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-30 with Science categories.
Nucleic acids have structurally evolved over billions of years to effectively store and transfer genetic information. In the 1980s, Nadrian Seeman’s idea of constructing a 3D lattice from DNA led to utilizing DNA as nanomolecular building blocks to create emergent molecular systems and nanomaterial objects. This bottom-up approach to construct nanoscale architectures with DNA marked the beginning of a new field, DNA nanotechnology, contributing significantly to the broad area of nanoscience and nanotechnology. The molecular architectonics of small "designer" molecules and short DNA sequences through complementary binding interaction engenders well-defined functional nanoarchitectures with realistic applications in areas ranging from biology to materials science and is termed "DNA nanoarchitectonics." This book discusses novel approaches adapted by leading researchers from all over the world to create functional nucleic acid molecular systems and nanoarchitectures. Individual chapters contributed by active practitioners provide fundamental and advanced knowledge emanated from their own and others’ work. Each chapter includes numerous illustrations, historical perspectives, case studies and practical examples, critical discussions, and future prospects. This book can serve as a practical handbook or as a textbook for advanced undergraduate- and graduate-level students of nanotechnology and DNA nanotechnology, supramolecular chemistry, and nanoarchitectonics and researchers working on macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in sensors, biosensors, nanoswitches and nanodevices, diagnostics, drug delivery, and therapeutics.
New Technologies For Energy Transition Based On Sustainable Development Goals
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Author : Kaviyarasu Kasinathan
language : en
Publisher: Springer Nature
Release Date :
New Technologies For Energy Transition Based On Sustainable Development Goals written by Kaviyarasu Kasinathan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.