Numerical Modeling Of Covid 19 Neurological Effects

DOWNLOAD

Download Numerical Modeling Of Covid 19 Neurological Effects PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Numerical Modeling Of Covid 19 Neurological Effects book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Numerical Modeling Of Covid 19 Neurological Effects

DOWNLOAD
Author : William Schiesser
language : en
Publisher: CRC Press
Release Date : 2021-12-26

Numerical Modeling Of Covid 19 Neurological Effects written by William Schiesser and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-26 with Mathematics categories.

Covid-19 is primarily a respiratory disease which results in impaired oxygenation of blood. The O2-deficient blood then moves through the body, and for the study in this book, the focus is on the blood flowing to the brain. The dynamics of blood flow along the brain capillaries and tissue is modeled as systems of ordinary and partial differential equations (ODE/PDEs). The ODE/PDE methodology is presented through a series of examples, 1. A basic one PDE model for O2 concentration in the brain capillary blood. 2. A two PDE model for O2 concentration in the brain capillary blood and in the brain tissue, with O2 transport across the blood brain barrier (BBB). 3. The two model extended to three PDEs to include the brain functional neuron cell density. Cognitive impairment could result from reduced neuron cell density in time and space (in the brain) that follows from lowered O2 concentration (hypoxia). The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the blood/brain hypoxia models, such as changes in the ODE/PDE parameters (constants) and form of the model equations.

Numerical Modeling Of Covid 19 Neurological Effects

DOWNLOAD
Author : William Schiesser
language : en
Publisher: CRC Press
Release Date : 2021-12-27

Numerical Modeling Of Covid 19 Neurological Effects written by William Schiesser and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-27 with Mathematics categories.

Covid-19 is primarily a respiratory disease which results in impaired oxygenation of blood. The O2-deficient blood then moves through the body, and for the study in this book, the focus is on the blood flowing to the brain. The dynamics of blood flow along the brain capillaries and tissue is modeled as systems of ordinary and partial differential equations (ODE/PDEs). The ODE/PDE methodology is presented through a series of examples, 1. A basic one PDE model for O2 concentration in the brain capillary blood. 2. A two PDE model for O2 concentration in the brain capillary blood and in the brain tissue, with O2 transport across the blood brain barrier (BBB). 3. The two model extended to three PDEs to include the brain functional neuron cell density. Cognitive impairment could result from reduced neuron cell density in time and space (in the brain) that follows from lowered O2 concentration (hypoxia). The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the blood/brain hypoxia models, such as changes in the ODE/PDE parameters (constants) and form of the model equations.

Nonstandard Finite Difference Schemes Methodology And Applications

DOWNLOAD
Author : Ronald E Mickens
language : en
Publisher: World Scientific
Release Date : 2020-11-11

Nonstandard Finite Difference Schemes Methodology And Applications written by Ronald E Mickens and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-11 with Mathematics categories.

This second edition of Nonstandard Finite Difference Models of Differential Equations provides an update on the progress made in both the theory and application of the NSFD methodology during the past two and a half decades. In addition to discussing details related to the determination of the denominator functions and the nonlocal discrete representations of functions of dependent variables, we include many examples illustrating just how this should be done.Of real value to the reader is the inclusion of a chapter listing many exact difference schemes, and a chapter giving NSFD schemes from the research literature. The book emphasizes the critical roles played by the 'principle of dynamic consistency' and the use of sub-equations for the construction of valid NSFD discretizations of differential equations.

Innovative Data Integration And Conceptual Space Modeling For Covid Cancer And Cardiac Care

DOWNLOAD
Author : Amy Neustein
language : en
Publisher: Academic Press
Release Date : 2022-01-18

Innovative Data Integration And Conceptual Space Modeling For Covid Cancer And Cardiac Care written by Amy Neustein and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-18 with Science categories.

In recent years, scientific research and translation medicine have placed increased emphasis on computational methodology and data curation across many disciplines, both to advance underlying science and to instantiate precision-medicine protocols in the lab and in clinical practice. The nexus of concerns related to oncology, cardiology, and virology (SARS-CoV-2) presents a fortuitous context within which to examine the theory and practice of biomedical data curation. Innovative Data Integration and Conceptual Space Modeling for COVID, Cancer, and Cardiac Care argues that a well-rounded approach to data modeling should optimally embrace multiple perspectives inasmuch as data-modeling is neither a purely formal nor a purely conceptual discipline, but rather a hybrid of both. On the one hand, data models are designed for use by computer software components, and are, consequently, constrained by the mechanistic demands of software environments; data modeling strategies must accept the formal rigors imposed by unambiguous data-sharing and query-evaluation logic. In particular, data models are not well-suited for software-level deployment if such models do not translate seamlessly to clear strategies for querying data and ensuring data integrity as information is moved across multiple points. On the other hand, data modeling is, likewise, constrained by human conceptual tendencies, because the information which is managed by databases and data networks is ultimately intended to be visualized/utilized by humans as the end-user. Thus, at the intersection of both formal and humanistic methodology, data modeling takes on elements of both logico-mathematical frameworks (e.g., type systems and graph theory) and conceptual/philosophical paradigms (e.g., linguistics and cognitive science). The authors embrace this two-sided aspect of data models by seeking non-reductionistic points of convergence between formal and humanistic/conceptual viewpoints, and by leveraging biomedical contexts (viz., COVID, Cancer, and Cardiac Care) so as to provide motivating examples and case-studies in this volume. - Provides an analysis of how conceptual spaces and related cognitive linguistic approaches can inspire programming and query-processing models - Outlines the vital role that data modeling/curation has played in significant medical breakthroughs - Presents readers with an overview of how information-management approaches intersect with precision medicine, providing case studies of data-modeling in concrete scientific practice - Explores applications of image analysis and computer vision in the context of precision medicine - Examines the role of technology in scientific publishing, replication studies, and dataset curation

Machine Intelligence And Data Science Applications

DOWNLOAD
Author : Vaclav Skala
language : en
Publisher: Springer Nature
Release Date : 2022-08-01

Machine Intelligence And Data Science Applications written by Vaclav Skala and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-01 with Technology & Engineering categories.

This book is a compilation of peer reviewed papers presented at International Conference on Machine Intelligence and Data Science Applications (MIDAS 2021), held in Comilla University, Cumilla, Bangladesh during 26 – 27 December 2021. The book covers applications in various fields like image processing, natural language processing, computer vision, sentiment analysis, speech and gesture analysis, etc. It also includes interdisciplinary applications like legal, healthcare, smart society, cyber physical system and smart agriculture, etc. The book is a good reference for computer science engineers, lecturers/researchers in machine intelligence discipline and engineering graduates.

Human Ipsc Derived Disease Models For Drug Discovery

DOWNLOAD
Author : Markus H. Kuehn
language : en
Publisher: Springer Nature
Release Date : 2023-11-23

Human Ipsc Derived Disease Models For Drug Discovery written by Markus H. Kuehn and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-23 with Science categories.

Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has beenlost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.

Consequences Of The Covid 19 Pandemic On Care For Neurological Conditions

DOWNLOAD
Author : Cheng-Yang Hsieh
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-07

Consequences Of The Covid 19 Pandemic On Care For Neurological Conditions written by Cheng-Yang Hsieh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-07 with Medical categories.

Geospatial Technology For Human Well Being And Health

DOWNLOAD
Author : Fazlay S. Faruque
language : en
Publisher: Springer Nature
Release Date : 2022-03-21

Geospatial Technology For Human Well Being And Health written by Fazlay S. Faruque and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-21 with Science categories.

Over the last thirty years or so, there have been tremendous advancements in the area of geospatial health; however, somehow, two aspects have not received as much attention as they should have received. These are a) limitations of different spatial analytical tools and b) progress in making geospatial environmental exposure data available for advanced health science research and for medical practice. This edited volume addresses those two less explored areas of geospatial health with augmented discussions on the theories, methodologies and limitations of contemporary geospatial technologies in a wide range of applications related to human well-being and health. In 20 chapters, readers are presented with an up-to-date assessment of geospatial technologies with an emphasis on understanding general geospatial principles and methodologies that are often overlooked in the research literature. As a result, this book will be of interest to both newcomers and experts in geospatial analysis and will appeal to students and researchers engaged in studying human well-being and health. Chapters are presenting new concepts, new analytical methods and contemporary applications within the framework of geospatial applications in human well-being and health. The topics addressed by the various chapter authors include analytical approaches, newer areas of geospatial health application, introduction to unique resources, geospatial modeling, and environmental pollution assessments for air, water and soil. Although geospatial experts are expected to be the primary readers, this book is designed in such a way so that the public health professionals, environmental health scientists and clinicians also find it useful with or without any familiarity with geospatial analysis.

Language Case Files In Neurological Disorders

DOWNLOAD
Author : Louise Cummings
language : en
Publisher: Routledge
Release Date : 2021-08-30

Language Case Files In Neurological Disorders written by Louise Cummings and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-30 with Language Arts & Disciplines categories.

This book features case studies of ten individuals with acquired neurological disorders. These disorders have implications for speech, language, and communication, but to date they have not been the focus of research in speech-language pathology. Chapters present a brief medical overview of each condition, followed by detailed linguistic analysis. A carefully assembled narrative captures the impact of each neurological disorder on an individual’s daily life and social activities. This structured approach, supported by further reading and exercises, gives readers a nuanced understanding of each disorder's clinical presentation and language and communication features, and the complex interrelationship between language, communication, and cognitive and motor symptoms. The book will be of interest to students of all levels, researchers, and clinicians in speech-language pathology and related disciplines, including neurology, psychiatry, and psychology.

Cognitive Psychological And Psychiatric Consequences Of The Coronavirus Covid 19 Pandemic In The Population Of Older Persons With Cognitive Impairment Dementia And Or Neuropsychiatric Disorders

DOWNLOAD
Author : Gianfranco Spalletta
language : en
Publisher: Frontiers Media SA
Release Date : 2021-12-20

Cognitive Psychological And Psychiatric Consequences Of The Coronavirus Covid 19 Pandemic In The Population Of Older Persons With Cognitive Impairment Dementia And Or Neuropsychiatric Disorders written by Gianfranco Spalletta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-20 with Medical categories.