Numerical Simulation Of Blood Flow In The Stenotic Carotid Artery Bifurcation

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Numerical Simulation Of Blood Flow In The Stenotic Carotid Artery Bifurcation

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Author : Jennifer Sara Stroud
language : en
Publisher:
Release Date : 2000

Numerical Simulation Of Blood Flow In The Stenotic Carotid Artery Bifurcation written by Jennifer Sara Stroud and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.

Numerical Simulation Of Blood Flow In The Stenotic Carotid Bifurcation

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Author : Vitaliy Lvovich Rayz
language : en
Publisher:
Release Date : 2005

Numerical Simulation Of Blood Flow In The Stenotic Carotid Bifurcation written by Vitaliy Lvovich Rayz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.

Numerical Simulations Of Blood Flow Through The Carotid Artery Bifurcation

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Author : Liang-Der Jou
language : en
Publisher:
Release Date : 1995

Numerical Simulations Of Blood Flow Through The Carotid Artery Bifurcation written by Liang-Der Jou and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.

Hemodynamic Analysis Of Blood Flows In Carotid Bifurcations

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Author : Xiaohong Yu
language : en
Publisher: Open Dissertation Press
Release Date : 2017-01-27

Hemodynamic Analysis Of Blood Flows In Carotid Bifurcations written by Xiaohong Yu and has been published by Open Dissertation Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with categories.

This dissertation, "Hemodynamic Analysis of Blood Flows in Carotid Bifurcations" by Xiaohong, Yu, 于曉紅, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled "Hemodynamic Analysis of Blood Flows in Carotid Bifurcations" Submitted by Yu Xiaohong for the degree of Doctor of Philosophy at The University of Hong Kong in April 2007 The hemodynamic mechanism for the initiation and development of atherosclerosis in the carotid artery has been investigated in detail by researchers. Regardless of the pathology of atherosclerosis (or, later, stenosis), once the constriction is present in the carotid artery, the flow pattern and other characteristics will be changed significantly near this diseased segment. Given the complex geometry and flow patterns in this artery, it is difficult to explore these changes experimentally. Computational fluid dynamics (CFD), developed rapidly in recent years, could be used to study various aspects of cardiovascular diseases and, consequently, help clinicians or physiologists to understand the mechanical environments in normal and diseased arteries or diseased organs. The present study mainly explores the numerical simulation and focuses on the flow property variation caused by different factors in the carotid bifurcation, such as flow division ratio between two exits, the stenosis severity, morphology of the stenosis, flow rate waveform, Womersley number of the inlet flow, and rheologic behavior of the blood. By inspecting these impacts, the present study provides a variety of pictures of blood flows in both normal and diseased carotid arteries, in which the wall shear stress distribution, pressure drop, flow patterns and some other hemodynamic characteristics are analyzed. From this information, the situation of the vessel wall and the blood are evaluated, and the risk of stroke for each situation is given. For the normal carotid artery, if the flow rate divided to the internal carotid artery (ICA) is smaller than the averaged one, the vessel wall near the sinus of the ICA will be in a worse condition. For the stenosed carotid artery, the severer the stenosis the larger the risk of stroke. For the different morphology of the constriction in a diseased carotid artery, the eccentric one seems to have a larger chance of developing stroke. In the realistic range of Womersley numbers for human beings, the larger the Womersley number the worse the condition of the vessel wall. As far as investigating the rheologic behavior of the blood is concerned, the Newtonian assumption for most of the study seems to overestimate the adverse environment of the vessel wall and the blood in a diseased carotid artery. DOI: 10.5353/th_b3864700 Subjects: Hemodynamics - Mathematical models Hemodynamics - Simulation methods Carotid artery - Diseases Cerebrovascular disease

Haemodynamics Of Arterial Organs

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Author : X. Y. Xu
language : en
Publisher: WIT Press (UK)
Release Date : 1999

Haemodynamics Of Arterial Organs written by X. Y. Xu and has been published by WIT Press (UK) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.

Partial Contents: Haemodynamics of the Reconstruction of Complex Cardiac Malformations; Simulation of Time-Dependent Blood Flow Past Valve Prostheses; Comparisons between Computational Haemodynamics, Photochromic Dye Flow Visualisation and Magnetic Resonance Velocimetry.

A Three Dimensional Computer Simulation Of A Compliant Human Carotid Artery Bifurcation

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Author : William Fekadu Asrat
language : en
Publisher:
Release Date : 1996

A Three Dimensional Computer Simulation Of A Compliant Human Carotid Artery Bifurcation written by William Fekadu Asrat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.

Numerical Simulation Of Blood Flow In Arterial Stenosis Under Steady And Pulsatile Flow Conditions

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Author : Parth Pranavbhai Dave
language : en
Publisher:
Release Date : 2011

Numerical Simulation Of Blood Flow In Arterial Stenosis Under Steady And Pulsatile Flow Conditions written by Parth Pranavbhai Dave and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Electronic dissertations categories.

Cardiovascular diseases (CVDs) are among the leading causes of death in the world. In this study, an attempt was made to model the flow dynamics of blood in abnormally narrowed artery. Finite volume solver FLUENT was used for the analysis with the aim of understanding the consequences of increasing the degree of stenosis using a two-equation turbulence model. The compliant nature of the artery was neglected, and Newtonian behavior of the blood flow was assumed for the larger arteries. Steady-flow simulations with 75% area reductions were used to establish the validity of the current models by employing the standard and transitional variant of the k -w turbulence models. Subsequently, it was found that transitional k -w model was suitable for the low Reynolds number internal flows associated with the transition to turbulence, although only a minor departure in terms of the turbulence intensity peak was observed. Unsteady blood flow was introduced by employing a sinusoidal pulsatile waveform at the inlet. The pulsatile nature of the blood flow was investigated in the range of the constriction ratio from 60% to 90%, with an inlet-specified pulse. It was hypothesized that the severity of the stenosis played a major role in the initiation of the turbulence, since no major turbulence was reported for the 60% and 75% area reductions, while increasing the constriction ratio of 90% significantly altered the flow dynamics and triggered the transition to turbulence much earlier than anticipated. The outcome of current numerical efforts was expressed in terms of wall shear stress, a hemodynamically relevant parameter.

Lagrangian Hemodynamics Of The Stenosed Carotid Bifurcation Microform

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Author : Mauro Tambasco
language : en
Publisher: National Library of Canada = Bibliothèque nationale du Canada
Release Date : 2002

Lagrangian Hemodynamics Of The Stenosed Carotid Bifurcation Microform written by Mauro Tambasco and has been published by National Library of Canada = Bibliothèque nationale du Canada this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.

The severity of a stenosis at the carotid artery bifurcation is commonly used as an indicator for assessing stroke-risk; however it has relatively poor specificity. Consequently, new diagnostic indicators are being sought to improve stroke-risk assessment. Previous work using computational simulations and experimental flow visualizations has demonstrated marked differences in local flow patterns between concentrically- and eccentrically-stenosed carotid bifurcation models having the same stenosis severity. Since local blood flow patterns are known to influence atherosclerotic plaque formation via deposition of monocytes, and clot formation via the deposition, shear activation, and aggregation of platelets at the stenosis apex, and the accumulation of fibrin in recirculating or stagnant zones, such differences in flow patterns may indicate differences in atherosclerotic and thromboembolic potential, and hence risk of ischemic stroke. To test this hypothesis, we developed novel computational techniques to track fluid elements (representing uniformly distributed blood particles) through these concentrically- and eccentrically-stenosed carotid bifurcation models, and computed and compared various path-dependent hemodynamic parameters between the models. One of the techniques developed is a method to accurately compute particle-to-wall distances for unstructured meshes comprised of linear or quadratic tetrahedral finite elements. This technique was necessary to compute accurate deposition patterns and densities of fluid elements, and to address numerical and conceptual difficulties associated with a fluid element traveling arbitrarily close to a model wall. Another technique was developed to assess the quality of the computed flow field for the purpose of subsequent particle tracking, which, when combined with the development of a physiologically based particle-seeding scheme, ensures that the hemodynamic parameters derived from the particle trajectories are computed correctly and accurately. The results of this thesis suggest that with the exception of residence time of fluid elements, some potentially significant differences exist between hemodynamic parameters derived from the concentric and eccentric stenosis models. More specifically, the magnitude of platelet shear exposure, the transit times and level of activation of platelets that exceed a given shear threshold, and the size and density of local platelet and monocyte deposition are higher in the eccentric model. Experimental work is required to assess the significance of these differences.

Finite Element Methods And Their Applications

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Author : Mahboub Baccouch
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-11-17

Finite Element Methods And Their Applications written by Mahboub Baccouch and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-17 with Computers categories.

This book provides several applications of the finite element method (FEM) for solving real-world problems. FEM is a widely used technique for numerical simulations in many areas of physics and engineering. It has gained increased popularity over recent years for the solution of complex engineering and science problems. FEM is now a powerful and popular numerical method for solving differential equations, with flexibility in dealing with complex geometric domains and various boundary conditions. The method has a wide range of applications in various branches of engineering such as mechanical engineering, thermal and fluid flows, electromagnetics, business management, and many others. This book describes the development of FEM and discusses and illustrates its specific applications.

Numerical Simulation Of Blood Flow And Vessel Wall Stresses In Stenosed Arteries

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Author : Li M. Mingxiu
language : en
Publisher:
Release Date : 2007

Numerical Simulation Of Blood Flow And Vessel Wall Stresses In Stenosed Arteries written by Li M. Mingxiu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.