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O Sagrado E A Hist Ria


O Sagrado E A Hist Ria
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O Sagrado E A Hist Ria


O Sagrado E A Hist Ria
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Author : André Eduardo Guimarães
language : pt-BR
Publisher: EDIPUCRS
Release Date : 2000

O Sagrado E A Hist Ria written by André Eduardo Guimarães and has been published by EDIPUCRS this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with History categories.




Translational Medicine


Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26

Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.


Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.



Filosofia E Histria Da Cincia No Cone Sul Seleo De Trabalhos Do 5o Encontro


Filosofia E Histria Da Cincia No Cone Sul Seleo De Trabalhos Do 5o Encontro
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Author : Roberto Martins
language : pt
Publisher: Lulu.com
Release Date : 2008-04-01

Filosofia E Histria Da Cincia No Cone Sul Seleo De Trabalhos Do 5o Encontro written by Roberto Martins and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-01 with Science categories.


This book contains a selection of papers presented at the V South Cone Meeting of Philosophy and History of Science (Florianópolis, Brazil, May 2006). The language of the chapters is Portuguese, Spanish or English. Published by the South Cone Association for Philosophy and History of Science, www.afhic.org.



Filosofia E Histria Da Cincia No Cone Sul 3 Encontro


Filosofia E Histria Da Cincia No Cone Sul 3 Encontro
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Author : Roberto Martins
language : es
Publisher: Lulu.com
Release Date : 2008-05-01

Filosofia E Histria Da Cincia No Cone Sul 3 Encontro written by Roberto Martins and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-01 with Science categories.


A selection of papers presented at the III South Cone Meeting of Philosophy and History of Science (Águas de Lindóia, SP, Brazil, 27-30 May 2002). Papers are in Portuguese and Spanish.



O Leviat E A Coruja Ci Ncia Mito E Raz O


O Leviat E A Coruja Ci Ncia Mito E Raz O
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Author : Arthur Barthelmess
language : pt-BR
Publisher: Lulu.com
Release Date : 2012-09-29

O Leviat E A Coruja Ci Ncia Mito E Raz O written by Arthur Barthelmess and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-29 with Religion categories.


Admitindo tratar-se de uma dualidade estrutural do psiquismo, propõe o Ensaio, fundamentar o entendimento em bases abrangentes que permitam encarar sem escândalo os monstros míticos que assolam nosso âmago mais secreto, para abordar, por fim, sem preconceito - e sem pieguice, o perpétuo problema antropológico quanto ao Sagrado.



O Panorama


O Panorama
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Author :
language : en
Publisher:
Release Date : 1842

O Panorama written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1842 with categories.




Blacks In Colonial Veracruz


Blacks In Colonial Veracruz
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Author : Patrick J. Carroll
language : en
Publisher: University of Texas Press
Release Date : 2010-06-28

Blacks In Colonial Veracruz written by Patrick J. Carroll and has been published by University of Texas Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-28 with Social Science categories.


Beginning with the Spanish conquest, Mexico has become a racially complex society intermixing Indian, Spanish, and African populations. Questions of race and ethnicity have fueled much political and scholarly debate, sometimes obscuring the experiences of particular groups, especially blacks. Blacks in Colonial Veracruz seeks to remedy this omission by studying the black experience in central Veracruz during virtually the entire colonial period. The book probes the conditions that shaped the lives of inhabitants in Veracruz from the first European contact through the early formative period, colonial years, independence era, and the postindependence decade. While the primary focus is on blacks, Carroll relates their experience to that of Indians, Spaniards, and castas (racially hybrid people) to present a full picture of the interplay between local populations, the physical setting, and technological advances in the development of this important but little-studied region.



Evolution Of Sanitation And Wastewater Technologies Through The Centuries


Evolution Of Sanitation And Wastewater Technologies Through The Centuries
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Author : Andreas N. Angelakis
language : en
Publisher: IWA Publishing
Release Date : 2014-09-14

Evolution Of Sanitation And Wastewater Technologies Through The Centuries written by Andreas N. Angelakis and has been published by IWA Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-14 with Science categories.


Most of the technological developments relevant to water supply and wastewater date back to more than to five thousand years ago. These developments were driven by the necessity to make efficient use of natural resources, to make civilizations more resistant to destructive natural elements, and to improve the standards of life, both at public and private level. Rapid technological progress in the 20th century created a disregard for past sanitation and wastewater and stormwater technologies that were considered to be far behind the present ones. A great deal of unresolved problems in the developing world related to the wastewater management principles, such as the decentralization of the processes, the durability of the water projects, the cost effectiveness, and sustainability issues, such as protection from floods and droughts were intensified to an unprecedented degree. New problems have arisen such as the contamination of surface and groundwater. Naturally, intensification of unresolved problems has led to the reconsideration of successful past achievements. This retrospective view, based on archaeological, historical, and technical evidence, has shown two things: the similarity of physicochemical and biological principles with the present ones and the advanced level of wastewater engineering and management practices. Evolution of Sanitation and Wastewater Technologies through the Centuries presents and discusses the major achievements in the scientific fields of sanitation and hygienic water use systems throughout the millennia, and compares the water technological developments in several civilizations. It provides valuable insights into ancient wastewater and stormwater management technologies with their apparent characteristics of durability, adaptability to the environment, and sustainability. These technologies are the underpinning of modern achievements in sanitary engineering and wastewater management practices. It is the best proof that “the past is the key for the future”. Evolution of Sanitation and Wastewater Technologies through the Centuries is a textbook for undergraduate and graduate courses of Water Resources, Civil Engineering, Hydraulics, Ancient History, Archaeology, Environmental Management and is also a valuable resource for all researchers in the these fields. Authors: Andreas N. Angelakis, Institute of Iraklion, Iraklion, Greece and Joan B. Rose, Michigan State University, East Lansing, MI, USA



Ayahuasca Religions


Ayahuasca Religions
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Author : Beatriz Caiuby Labate
language : en
Publisher: Multidisciplinary Association for Psychedelic Studies
Release Date : 2008

Ayahuasca Religions written by Beatriz Caiuby Labate and has been published by Multidisciplinary Association for Psychedelic Studies this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Body, Mind & Spirit categories.


The last two decades have seen a broad expansion of the ayahuasca religions, and it has also witnessed, especially since the millennium, an explosion of studies into the spiritual uses of ayahuasca. Ayahuasca Religions grew out of the need for an ordering of the profusion of titles related to this subject that are now appearing. This publication offers a map of the global production of literature on this theme. Three researchers located in different cities (Beatriz Caiuby Labate in São Paulo, Rafael Guimarães dos Santos in Barcelona, and Isabel Santana de Rose in Florianapolis, Brazil) worked in a virtual research group for a year to compile a list of bibliographical references on Santo Daime, Barquinha, UDV and urban ayahuasqueiros, including the specialized academic literature as well as esoteric and experiential writings produced by participants of these churches. Ayahuasca Religions presents the results of that collaboration. Ayahuasca Religions includes two essays commenting on aspects of the bibliography. The first presents a profile of these religious groups, including their history and expansion, and a general assessment of the principal characteristics, tendencies, and perspectives evident in the literature about them. The second essay summarizes the most important studies of human subjects in the context of Santo Daime, Unio do Vegetal and Barquinha, evaluating their results, contributions, and limitations. The essay also offers some preliminary anthropological reflections on biomedical research of ayahuasca.



Gabinete Historico A History Of Portugal To 1775


Gabinete Historico A History Of Portugal To 1775
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Author :
language : pt-BR
Publisher:
Release Date : 1819

Gabinete Historico A History Of Portugal To 1775 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1819 with categories.