Ocular Circulation And Neovascularization
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Ocular Circulation And Neovascularization
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Author : D. Benezra
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Ocular Circulation And Neovascularization written by D. Benezra and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Neovascularization isanormalphaseoftissue repair mechanlsm. In theeye, however, sproutingofnewvessels withinavasculartissuesandtheirgreatertendencytobleed havedetrimentaleffectsonvision. Diabeticretinopathy, corneal neovascularization, age-related macular degeneration, retinal veinocclusion, andretinopathy of prematurity are major causes of blindness. In all, uncontrolled proliferationofnewvesselsistheunderlying pathologicalcauseleadingtotheinexorablelossofvision. Development of lasertechnologiesandtheir wide use in ophthalmology have broughtsomehopeforthetreqtment of these diseases. However, itbecameevident that direct closureofthenewvesselsand/orablationoflargepartsof thetissuearenotidealsolutionstotheproblem. Recent advances in molecular biology and genetic engineering have fosteredbasic knowledge regarding the growth factors and intercellular messengers and their association with theproliferationofnew blood vessels. These latter findings sparked a renewed interest in Michaelson's "X-factor" ofocular neovascularization and opened avenues for possible innovative therapeutic approaches. Therefore, the suggestion to organize an international gathering of clinicians and scientists interested in problems of ocular circulation and neovascularization was received with great enthusiasm. Unanimously, it wasdecidedtodedicatethe symposium to Professor I.C. Michaelson, theinnovativescientist, the greatclinician, theindefatigableteacher, andaboveall, thewonderfulhumanbeing. The meeting was highlighted by the outstanding atmosphere of friendshipandscientif·ic exchanges. This book mirrors the information delivered and includes a selectionofpapersfromthescientificprogram. Theorganizationofthismeetingandthepublicationof thebookwouldnothavebeenpossiblewithouttheharmonious teameffortsmadebytheInternational, ScientificandLocal Committees. I am thankful tothe chairpersons of the varioussessionsfortheirtime, keeninterestandendeavor for the realizationofahighscientific level. I also deeplyacknowledgethehelpand & upportofArnallPatz, Bob Murphy, BertGlaser, RobertFrank, LarryHjelmeland, Gordon Klintworth, Neville Welsh, Charles Riva, Alec Garner, DesmondArcher, EphraimFriedman, MyronYanoff, MosheLahav, Willem Manschot, Hans-WaltherLarsenand Masanobu Uyama. The powerful stimulus of Hanan Zauberman, Steve Ryan, GabrielCoscas, GiselleSoubrane, MosheIvry, YuvalYassur and Sue and Peter Ballenwasmost instrumental in the realizationofthese"dreams". Asalways, Iwasfortunate tohavetheinvaluablecollaborationofmyloyalassistants: Evelyne Cohen, Genia Maftzir, Israel Barzel, Arieh Zelikovitch, andJudithBenEzra. Thesmoothrunningofthe meeting andtimelyeditingofthebookcouldnothave been possible without theincalculablehelp and indefatigable typing and councilofJudithFisher, whoseconded me in selectingthepapersandeditingthebook
Retinal And Choroidal Vascular Diseases Of The Eye
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Author : Jay Chhablani
language : en
Publisher: Elsevier
Release Date : 2024-03-09
Retinal And Choroidal Vascular Diseases Of The Eye written by Jay Chhablani and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-09 with Science categories.
Retinal and Choroidal Vascular Diseases of the Eye explores a variety of retinal and choroidal vascular diseases, covering their pathogenesis, clinical features, and management strategies. The book begins with an outline of the basic features of retinal and choroidal vasculature before moving on to imaging techniques. Chapters then delve into specific diseases and abnormalities, as well as vascular diseases that are associated with systemic inflammatory diseases. The book then moves onto considering vascular diseases associated with system conditions before considering vascular tumors. Recent innovations and upcoming treatment options are also explored for the various diseases throughout the book. This comprehensive reference provides a deep dive into vascular diseases of the eye, and is a must-have reference for ophthalmologists, medical and surgical retina specialists, and researchers in related fields - Explores numerous retinal and choroidal disease entities and their pathogenic mechanisms - Features multimodal images to help illustrate and describe the disease entities - Discusses innovative treatment options for choroidal vascular diseases - Considers the latest clinical trials related to retinal and choroidal disorders, and provides key learnings
Choroidal Neovascularization
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Author : Jay Chhablani
language : en
Publisher: Springer Nature
Release Date : 2020-07-31
Choroidal Neovascularization written by Jay Chhablani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-31 with Medical categories.
The book discusses all aspects of choroidal neovascularization (CNV), including the basics, clinical conditions associated with CNV, clinical trials related to CNV, future directions and rehabilitation. The first section covers the pathogenesis, proposed mechanisms, disease models, histopathology and electronmicroscopy. The next section explores CNV secondary to various clinical conditions, such as age-related macular degeneration (AMD), myopia, and less common conditions like choroidal osteoma. The book also covers clinical features, imaging characteristics, and treatment approaches, as well as clinical trials in CNV conditions with recent updates. Lastly, it features chapters on stem cell therapy, gene therapy, new molecules, and lasers, as well as a section on rehabilitation, which addresses home monitoring and low vision aids. This book is intended for retina specialists, retina fellows and general ophthalmologists.
Corneal Angiogenesis
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Author : Gordon K. Klintworth
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Corneal Angiogenesis written by Gordon K. Klintworth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In this research monograph, the noted scholar Dr. Gordon K. Klintworth brings together all the available information on the pathogenesis of corneal neovascularization. This book should be a valuable contribution to the medical literature of ophthalmology and clinical pathology. Despite its relatively simple structure the cornea possesses many unique properties. These attributes include its crystal clarity and avascularity in the health state. This normally transparent structure has been the focal point for Dr. Klintworth's research endeavors for more than two decades. This monograph summarizes current knowledge about angiogenesis within this tissue as well as information about the related issue of the cornea's normal avascularity. The text provides a comprehensive overview of the topic based on studies by a large number of investigators who were either concerned with corneal neovascularization in particular or angiogenesis in general.
Neovascular Glaucoma
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Author : Mary Qiu
language : en
Publisher: Springer Nature
Release Date : 2022-12-13
Neovascular Glaucoma written by Mary Qiu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-13 with Medical categories.
This book offers a comprehensive overview of neovascular glaucoma (NVG), which is an extraordinarily aggressive type of secondary glaucoma that has often been discussed as an afterthought rather than the focal subject in glaucoma reference books. NVG is considered an end stage complication in patients with certain underlying retinal diseases, most commonly diabetic retinopathy and retinal vein occlusions. Historically, NVG has been one of the most difficult types of glaucoma to manage, with a high failure rate for traditional glaucoma surgery, and often progression of the underlying retinal disease despite “standard of care” treatment. Chapters cover advancements made in recent years in the management of the underlying ischemic retinal conditions that lead to NVG, including the use of anti-vascular endothelial growth factor (anti-VEGF) medications. Additionally, chapters discuss glaucoma surgeries, which have become less invasive in recent years with the advent of microinvasive glaucoma surgery (MIGS). This book offers an up-to-date reference regarding current concepts in the diagnosis, as well as medical, laser, and surgical treatment of NVG in the anti-VEGF era, with attention to the close collaboration between glaucoma specialists and retina specialists. Neovascular Glaucoma - Current Concepts in Diagnosis and Treatment will change the way ophthalmologists manage NVG, ensuring patients better outcomes. It is a must-have resource for ophthalmologists worldwide.
Uveitis Update
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Author : David Benezra
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 1999-01-01
Uveitis Update written by David Benezra and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-01 with Medical categories.
In this publication, worldwide renowned experts elucidate the ocular phenomenon of uveitis (intraocular inflammation) from different points of view. Summaries of the present knowledge along with detailed outlooks regarding the possibilities of future developments in clinical and basic sciences make 'Uveitis Update' an outstanding compendium of the state of the art in uveitis. The practicing ophthalmologist as well as the internist will find this book a practical guide on the latest treatment methods for uveitis together with a realistic look at future avenues. For the ophthalmic scientist and the ophthalmologist specialized in ocular immunology and inflammation, chapters like 'Newer Methodologies in Immunohistochemistry and Diagnosis', 'Ultrasound as a Diagnostic Tool in Uveitis: UBM and B-Scan', `The Role of Cytokines in Uveitis' or `Management of Ocular Manifestations in AIDS patients' will be of utmost importance.
National Library Of Medicine Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1987
National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medicine categories.
Focus On Macular Degeneration Research
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Author : O. R. Ioseliani
language : en
Publisher: Nova Publishers
Release Date : 2004
Focus On Macular Degeneration Research written by O. R. Ioseliani and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
Degeneration of the macula is the leading cause of legal blindness in people over fifty-five. The macula is used for most acute and detailed vision -- reading, driving, watching television, precise work, and recognising faces. However, this weakening of central vision does not necessarily affect colour and peripheral vision. Macular degeneration generally takes place over a gradual period and at different rates in each eye. Its causes are still unclear, but there exist two main types. 'Dry' degeneration occurs when the macular tissues of the retina thin and disturb pigmentation, and 'wet' includes bleeding and scar tissue. Though macular degeneration is usually age-related, there are forms that affect younger individuals, but the reasons behind those cases are not yet known. This new book provides state-of-the-art research results on this debilitating condition.
The Retina A Model For Cell Biology Studies Part 2
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Author : Ruben Adler
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Retina A Model For Cell Biology Studies Part 2 written by Ruben Adler and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Retina: A Model for Cell Biology Studies, Part II, is the second of a two-part series that details developments in the study of retinal cell biology. The book begins with a review of the current evidence for the role of putative neurotransmitters at particular synapses in the retina. It then discusses pre- and postsynaptic regulatory mechanisms; the interactions of neurotransmitter-neuromodulatory systems; and cellular effects of putative neurotransmitters and neuromodulators. This is followed by an introduction to vision psychophysics, showing its application in studying the functioning of cells in the retina. The remaining chapters discuss how the retinal pigment epithelium cell might be used as a model for studying biological problems of current interest; extracellular matrix molecules; concepts and controversies regarding the biology of endothelial cells, the key elements in the phenomenon of intraocular neovascularization; the use of genetic mutations and genetic mosaics for the study of the retina; and the retina as a regenerating organ.
Drug Discovery And Evaluation Pharmacological Assays
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Author : Hans G. Vogel
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-06-13
Drug Discovery And Evaluation Pharmacological Assays written by Hans G. Vogel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-13 with Medical categories.
Now expanded and updated to include molecular biology and genetic engineering techniques. The second edition of this successful reference book contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. The enclosed and fully searchable CD ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.