Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 471 Bacterial Reverse Mutation Test
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Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 471 Bacterial Reverse Mutation Test
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 1997-07-21
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 471 Bacterial Reverse Mutation Test written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-07-21 with categories.
The bacterial reverse mutation test uses amino-acid requiring at least five strains of Salmonella typhimurium and Escherichia coli to detect point mutations by base substitutions or frameshifts. The principle of this bacterial reverse mutation test ...
Oecd Series On Testing And Assessment Overview On Genetic Toxicology Tgs
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2017-04-13
Oecd Series On Testing And Assessment Overview On Genetic Toxicology Tgs written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-13 with categories.
Following a general update of the Genetic Toxicology TGs in 2015, the present Document was written to provide succinct and useful information to individuals unfamiliar with genetic toxicology testing, as well as experienced individuals wishing to obtain an overview of the recent changes that ...
Oecd Series On Testing And Assessment Guidance Document On Good In Vitro Method Practices Givimp
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2018-12-10
Oecd Series On Testing And Assessment Guidance Document On Good In Vitro Method Practices Givimp written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-10 with categories.
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
A Practical Guide To Toxicology And Human Health Risk Assessment
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Author : Laura Robinson
language : en
Publisher: John Wiley & Sons
Release Date : 2018-11-05
A Practical Guide To Toxicology And Human Health Risk Assessment written by Laura Robinson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-05 with Science categories.
Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.
Drug Safety Evaluation
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Author : Shayne Cox Gad
language : en
Publisher: John Wiley & Sons
Release Date : 2016-12-01
Drug Safety Evaluation written by Shayne Cox Gad and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-01 with Medical categories.
This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including local tissue tolerance, target organ toxicity and carcinogenicity, developmental toxicity, immunogenicity, and immunotoxicity Covers the development of new small and large molecules, generics, 505(b)(2) route NDAs, and biosimilars Revises material to reflect new drug products (small synthetic, large proteins and cells, and tissues), harmonized global and national regulations, and new technologies for safety evaluation Adds almost 20% new and thoroughly updates existing content from the last edition
Synthetics Mineral Oils And Bio Based Lubricants
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Author : Leslie R. Rudnick
language : en
Publisher: CRC Press
Release Date : 2020-01-29
Synthetics Mineral Oils And Bio Based Lubricants written by Leslie R. Rudnick and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-29 with Science categories.
Highlighting the major economic and industrial changes in the lubrication industry since the first edition, Synthetics, Mineral Oils, and Bio-Based Lubricants: Chemistry and Technology, Third Edition highlights the major economic and industrial changes in the lubrication industry and outlines the state of the art in each major lubricant application area. Chapters cover the use of lubricant fluids, growth or decline of market areas and applications, potential new applications, production capacities, and regulatory issues, including biodegradability, toxicity, and food production equipment lubrication. The highly-anticipated third edition features new and updated chapters including those on automatic and continuously variable transmission fluids, fluids for food-grade applications, oil-soluble polyalkylene glycols, functional bio-based lubricant base stocks, farnesene-derived polyolefins, estolides, bio-based lubricants from soybean oil, and trends in construction equipment lubrication. Features include: Contains an index of terms, acronyms, and analytical testing methods. Presents the latest conventions for describing upgraded mineral oil base fluids. Considers all the major lubrication areas: engine oils, industrial lubricants, food-grade applications, greases, and space-age applications Includes individual chapters on lubricant applications—such as environmentally friendly, disk drive, and magnetizable fluids—for major market areas around the globe. In a single, unique volume, Synthetics, Mineral Oils, and Bio-Based Lubricants: Chemistry and Technology, Third Edition offers property and performance information of fluids, theoretical and practical background to their current applications, and strong indicators for global market trends that will influence the industry for years to come.
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 2 Safety Assessment And Toxicologic Pathology
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Author : Wanda M. Haschek
language : en
Publisher: Academic Press
Release Date : 2023-02-18
Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 2 Safety Assessment And Toxicologic Pathology written by Wanda M. Haschek and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-18 with Medical categories.
Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to five separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 2: Toxicologic Pathology in Safety Assessment is an essential part of the most authoritative reference on toxicologic pathology principles and techniques for assessing product safety and human risk. Volume 2 describes the integration of product-induced structural and functional changes in tissues and the interpretation of their biological implications. Completely revised with many new chapters, Volume 2 of the Fourth Edition covers product safety assessment from many angles including current and emerging issues in toxicologic pathology for many product classes. Volume 2 of the Handbook of Toxicologic Pathology is a key resource for pathologists, toxicologists, research scientists, and regulators who use toxicologic pathology methods to study and make decisions on product safety. - Previous chapters on such topics as drug discovery and development, toxicity and carcinogenicity testing, report preparation, and risk assessment and communication have undergone extensive revision that includes in-depth discussion of new developments in the field - New chapters consider fundamental attributes for additional product classes including protein therapeutics, nucleic acid pharmaceutical agents, gene therapy and gene editing, stem cell and other cell therapies, vaccines, agricultural and bulk chemicals, and assigning adversity - Chapters dealing with product-specific practices address pathology and regulatory issues - Chapters offer high-quality and up-to-date content in a trusted work written by the collaborative efforts of many leading international subject matter experts - Hundreds of full-color images and diagrams are featured in both the print and electronic versions of this book to illustrate classic examples and highlight difficult concepts
Biomarkers In Toxicology
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Author : Ramesh C Gupta
language : en
Publisher: Academic Press
Release Date : 2019-02-13
Biomarkers In Toxicology written by Ramesh C Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-13 with Medical categories.
Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. - Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers - Includes completely revised chapters, along with additional chapters on the newest developments in the field - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more
Food Safety And Human Health
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Author : Ram Lakhan Singh
language : en
Publisher: Academic Press
Release Date : 2019-07-30
Food Safety And Human Health written by Ram Lakhan Singh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-30 with Medical categories.
Despite advances in hygiene, food treatment, and food processing, diseases caused by foodborne pathogens continue to constitute a worldwide public health concern. Ensuring food safety to protect public health remains a significant challenge in both developing and developed nations. Food Safety and Human Health provides a framework to manage food safety risks and assure a safe food system. Political, economic, and ecological changes have led to the re-emergence of many foodborne pathogens. The globalization of food markets, for example, has increased the challenge to manage the microbial risks. This reference will help to identify potential new approaches in the development of new microbiologically safe foods that will aid in preventing food borne illness outbreaks and provides the basic principles of food toxicology, food processing, and food safety. Food Safety and Human Health is an essential resource to help students, researchers, and industry professionals understand and address day-to-day problems regarding food contamination and safety. - Encompasses the first pedagogic treatment of the entire range of toxic compounds found naturally in foods or introduced by industrial contaminatio - Identifies areas of vital concern to consumers, such as toxicological implications of food, and human health implications of food processing - Focuses on safety aspects of genetically modified foods and the range of processing techniques along with the important food safety laws
Handbook Of Cosmetic Science And Technology
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Author : Frank Dreher
language : en
Publisher: CRC Press
Release Date : 2022-08-11
Handbook Of Cosmetic Science And Technology written by Frank Dreher and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-11 with Medical categories.
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice