Oecd Series On Testing And Assessment Fish Toxicity Testing Framework
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Oecd Series On Testing And Assessment Fish Toxicity Testing Framework
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2014-09-03
Oecd Series On Testing And Assessment Fish Toxicity Testing Framework written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-03 with categories.
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 203 Fish Acute Toxicity Test
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2025-06-25
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 203 Fish Acute Toxicity Test written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with categories.
The fish are exposed to the test substance preferably for a period of 96 hours. Mortalities are recorded at 24, 48, 72 and 96 hours and the concentrations which kill 50 per cent of the fish (LC50) are determined where possible. One or more species ...
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 243 Lymnaea Stagnalis Reproduction Test
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2016-07-29
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 243 Lymnaea Stagnalis Reproduction Test written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-29 with categories.
This Test Guideline is designed to assess effects of prolonged exposure to chemicals on the reproduction and survival of the hermaphrodite freshwater snail Lymnaea stagnalis (the Great Pond Snail).
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 210 Fish Early Life Stage Toxicity Test
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2025-06-25
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 210 Fish Early Life Stage Toxicity Test written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with categories.
The test method described in this Test Guideline, is intended to define the lethal and sub-lethal effects of chemicals on the early life stages of the species tested. The early-life stages of fish are exposed to five concentrations of the test ...
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 240 Medaka Extended One Generation Reproduction Test Meogrt
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2023-07-04
Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 240 Medaka Extended One Generation Reproduction Test Meogrt written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-04 with categories.
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 423 Acute Oral Toxicity Acute Toxic Class Method
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2002-02-08
Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 423 Acute Oral Toxicity Acute Toxic Class Method written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-02-08 with categories.
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
Statistical Analysis Of Ecotoxicity Studies
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Author : John W. Green
language : en
Publisher: John Wiley & Sons
Release Date : 2018-08-14
Statistical Analysis Of Ecotoxicity Studies written by John W. Green and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-14 with Science categories.
A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.
An Introduction To Interdisciplinary Toxicology
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Author : Carey N. Pope
language : en
Publisher: Academic Press
Release Date : 2020-02-18
An Introduction To Interdisciplinary Toxicology written by Carey N. Pope and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-18 with Technology & Engineering categories.
An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. - Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity - Includes a variety of perspectives to give a complete understanding of toxicology - Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained
Endocrine Disrupters
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Author : Peter Matthiessen
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-04
Endocrine Disrupters written by Peter Matthiessen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-04 with Science categories.
Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals both man-made and natural that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including: Crustaceans and mollusks Insects Fish Amphibians and reptiles Birds and mammals Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.
Animal Experimentation
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Author : Vaughan Monamy
language : en
Publisher: Cambridge University Press
Release Date : 2017-02-23
Animal Experimentation written by Vaughan Monamy and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-23 with Law categories.
This updated third edition is an essential overview for teachers and students in medical and biological sciences, and for those who conduct animal-based research.