Of Mice And Genes
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The Mouse In Animal Genetics And Breeding Research
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Author : Eugene J Eisen
language : en
Publisher: World Scientific
Release Date : 2005-06-27
The Mouse In Animal Genetics And Breeding Research written by Eugene J Eisen and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-27 with Science categories.
The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed the genetic contributions the mouse has made across the spectrum of the life sciences; this book aims to fill that vacuum. Mouse genetics research has made enormous contributions to the understanding of basic genetics, human genetics, and livestock genetics and breeding. The wide-ranging topics in the book include the mouse genome sequencing effort, molecular dissection of quantitative traits, embryo biotechnology, ENU mutagenesis, and genetics of disease resistance, and have been written by experts in their respective fields.
Contributions To Behavior Genetic Analysis
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Author : Gardner Lindzey
language : en
Publisher: Ardent Media
Release Date : 1970
Contributions To Behavior Genetic Analysis written by Gardner Lindzey and has been published by Ardent Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Science categories.
Origins Of Inbred Mice
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Author : Herbert C. III Morse
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Origins Of Inbred Mice written by Herbert C. III Morse and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.
Origins of Inbred Mice documents the proceedings of a symposium on the state of knowledge on inbred mice held in Bethesda, Maryland, in 1978. The book is organized into seven parts. Part I provides introductory remarks on the history of the development of inbred mice. Part II contains papers that examine mutations of inbred strains of mice. Part III contains studies dealing with viruses that affect inbred mice, including those that cause leukemia and mammary tumors. Part IV examines histocompatibility genes and their antigens; cell surface antigens of mouse leukemia; the characteristics of genes of the Tla region of the mouse; and the use of recombinant inbred strains in gene mapping. Part V presents studies on differences among sublines of inbred mouse strains. The papers in Part VI focus on wild mice, covering their classification and biochemical polymorphisms. Finally, Part VIII discusses the viruses, T locus, and histocompatibility antigens of wild mice.
The Coat Colors Of Mice
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Author : W.K. Silvers
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Coat Colors Of Mice written by W.K. Silvers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Many investigators seem to be fascinated by the coat colors of the mam mals with which they work. This seems to be the case particularly for those utilizing isogenic strains of mice, not only because such strains display wide ly different phenotypes, but because scientists, by definition, are an inquisi tive lot and it is sometimes difficult for the uninitiated to comprehend how such phenotypes are produced. This bewilderment becomes even more ap parent if the investigator happens to be involved in breeding studies and a number of attractively colored animals, quite different from the original stocks, appear. Thus I can recall numerous occasions when my colleagues, frequently working in areas completely unrelated to any aspect of genetics, have come to me with an attractively pigmented animal or, more likely, with a popUlation of segregating coat color types (usually because they have not tended their animals properly and have ended up with a cage full of F 2S displaying a number of different colors). How, they ask, do such colors come about? While in some cases it is easy to take chalk in hand and explain what has been going on (segregating) and why, in other cases it is virtually impossible. It is extremely difficult because while the interactions of many coat-color factors obey the simple laws of heredity and of predictable gene interactions, others do not.
Mouse Genetics
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Author : Shree Ram Singh
language : en
Publisher: Humana Press
Release Date : 2014-07-26
Mouse Genetics written by Shree Ram Singh and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-26 with Medical categories.
Mouse Genetics: Methods and Protocols provide selected mouse genetic techniques and their application in modeling varieties of human diseases. The chapters are mainly focused on the generation of different transgenic mice to accomplish the manipulation of genes of interest, tracing cell lineages and modeling human diseases. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, a list of necessary materials, systematic, readily reproducible methods and a notes section, which shares tips on troubleshooting in order to avoid known pitfalls. Comprehensive and authoritative, Mouse Genetics: Methods and Protocols promises to deliver fundamental techniques and protocols to geneticists, molecular biologists, cell and developmental biologists, students and postdoctoral fellows working in the various disciplines of mouse biology and modeling human disease.
The Colors Of Mice
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Author : M. Lynn Lamoreux
language : en
Publisher: John Wiley & Sons
Release Date : 2010-03-05
The Colors Of Mice written by M. Lynn Lamoreux and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-03-05 with Science categories.
Serving the needs of pigment cell biologists, cellular physiologists, developmental geneticists, researchers interested in melanoma and more, this new book showcases a blend of new technologies and new insights in the field of pigmantary genetics of mice, with comparative information on other animals. Graduate students can learn here the terminology and scope of the field, and animal fanciers can discover the genetics behind common color variants of mammals. The book is hailed for being written by four of the premier scientists in the field. These authors aim to present the molecular /cellular work in the context of phenotype and the interacting functions of genes that direct the development and function of one biological system. For other researchers, the depth of genetic knowledge on the pigmantary system makes it a valuable model for the study of other systems.
Mouse Genetics
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Author : Lee M. Silver
language : en
Publisher:
Release Date : 1995
Mouse Genetics written by Lee M. Silver and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Mice categories.
Genetics Of The Mouse
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Author : Jean Louis Guénet
language : en
Publisher: Springer
Release Date : 2014-12-09
Genetics Of The Mouse written by Jean Louis Guénet and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-09 with Science categories.
This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.
Microbial And Phenotypic Definition Of Rats And Mice
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1999-08-26
Microbial And Phenotypic Definition Of Rats And Mice written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-08-26 with Science categories.
US-Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US-Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic of Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes published in 1991. In addition to these publications, these meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats.
Techniques For The Genetic Analysis Of Brain And Behavior
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Author : D. Goldowitz
language : en
Publisher: Elsevier Publishing Company
Release Date : 1992
Techniques For The Genetic Analysis Of Brain And Behavior written by D. Goldowitz and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
The goal of this book is to provide a neurobehavioral context for the ever-growing list of single and multiple genes that play a role in brain structure and function. The chapters present strategies and techniques for the rigorous analysis of the genetic bases of brain and behavior, and discusses the practical and theoretical means to address these topics and provide the researcher with fine techniques for dissecting the genomic components of brain structure and behavioral function. This volume concentrates on techniques and approaches that have been largely developed with the house mouse, while providing a glimpse of genetic research with other species, such as the fruit fly, nematode worm and seaslug. Given the aim of doing genetic analysis of brain and behavior, this volume is an excellent overview of current techniques and recent innovations.