The Mouse In Animal Genetics And Breeding Research


The Mouse In Animal Genetics And Breeding Research
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The Mouse In Animal Genetics And Breeding Research


The Mouse In Animal Genetics And Breeding Research
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Author : Eugene J Eisen
language : en
Publisher: World Scientific
Release Date : 2005-06-27

The Mouse In Animal Genetics And Breeding Research written by Eugene J Eisen and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-06-27 with Science categories.


The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed the genetic contributions the mouse has made across the spectrum of the life sciences; this book aims to fill that vacuum. Mouse genetics research has made enormous contributions to the understanding of basic genetics, human genetics, and livestock genetics and breeding. The wide-ranging topics in the book include the mouse genome sequencing effort, molecular dissection of quantitative traits, embryo biotechnology, ENU mutagenesis, and genetics of disease resistance, and have been written by experts in their respective fields.



The Importance Of Laboratory Animal Genetics Health And The Environment In Biomedical Research


The Importance Of Laboratory Animal Genetics Health And The Environment In Biomedical Research
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Author : Edward C. Jr. Melby
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Importance Of Laboratory Animal Genetics Health And The Environment In Biomedical Research written by Edward C. Jr. Melby and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.


The Importance of Laboratory Animal Genetics, Health, and the Environment in Biomedical Research documents the proceedings of the Fifth Charles River International Symposium on Laboratory Animals, in Heidelberg, Federal Republic of Germany, March 14-16, 1983. These papers examine how the health and genetic monitoring of laboratory animals, coupled with environmental influences, affect the investigations of oncologists, toxicologists, or pharmacologists. The book is organized into four parts. Part I focuses on the health monitoring of laboratory animals for biomedical research. It includes studies on the effects of health and health monitoring in toxicology studies, oncology studies, and pharmacologic studies. Part II deals with the genetic monitoring of laboratory animals. It examines the causes of genetic alternation in laboratory animals and ways to prevent them. Part III considers the environmental monitoring that is necessary for research on laboratory animals. Part IV on new research frontiers includes studies on the production of monoclonal antibodies for the experimental and therapeutic modulation of laboratory animals, and the quality control aspects of animal experimentation.



Mouse Genetics


Mouse Genetics
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Author :
language : en
Publisher:
Release Date : 2001

Mouse Genetics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Mice categories.




The Mouse In Animal Genetics And Breeding Research


The Mouse In Animal Genetics And Breeding Research
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Author : Eugene J. Eisen
language : en
Publisher: World Scientific
Release Date : 2005

The Mouse In Animal Genetics And Breeding Research written by Eugene J. Eisen and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.


The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed the genetic contributions the mouse has made across the spectrum of the life sciences; this book aims to fill that vacuum. Mouse genetics research has made enormous contributions to the understanding of basic genetics, human genetics, and livestock genetics and breeding. The wide-ranging topics in the book include the mouse genome sequencing effort, molecular dissection of quantitative traits, embryo biotechnology, ENU mutagenesis, and genetics of disease resistance, and have been written by experts in their respective fields.Chapter 1: The Beginnings - Ode To A Wee Mouse (58 KB)



Animal Genetics


Animal Genetics
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Author : Leopold J. Rechi
language : en
Publisher:
Release Date : 2009

Animal Genetics written by Leopold J. Rechi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Animal genetics categories.


The fact that living things inherit traits from their parents has been used since prehistoric times to improve crop plants and animals through selective breeding. Many aspects of human and animal behaviors have a strong genetic contribution. Individual variation in different behaviors is also found across animal populations. Animal models are increasingly being used to look for genes underlying these naturally occurring variations in behaviors and the most common species of animals used experimentally are mice and rats. This new and important book gathers the latest research from around the globe in this dynamic field of study with a focus on such topics as: phylogeography of finches and sparrows, pig genomics and transgenesis in biomedical research, epigenetic regulation in bovine cells, understanding the stress response through mouse genetics and others.



The Mouse In Biomedical Research


The Mouse In Biomedical Research
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Author : Henry Foster
language : en
Publisher: Elsevier
Release Date : 1981-01-01

The Mouse In Biomedical Research written by Henry Foster and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-01-01 with Science categories.


The Mouse in Biomedical Research, Volume I: History, Genetics, and Wild Mice focuses on the utility of the mouse as a laboratory animal in biomedical research. A historical perspective on the development and origins of the laboratory and wild mouse is given. The diversity of inbred strains of mice as well as the methods of developing and the genetic monitoring and testing of these strains are discussed. This volume consists of 14 chapters and begins with an overview of mice of the genus Mus and problems concerning evolution within the genus. The following chapters focus on taxonomy, nomenclature, and breeding systems, together with recombinant inbred and congenic resistant mouse strains. Methods of constructing, testing, and monitoring strains are described. Congenic strains, gene mapping, cytogenetics, and murine experimental studies are also considered, along with the histocompatibility-2 complex and radiation genetics. The final chapter is devoted to the pharmacogenetics of the laboratory mouse, paying particular attention to intoxication and detoxication pathways, genetically determined differences in xenobiotic metabolism, and pharmacogenetic polymorphisms. This book will be a useful reference for investigators using mice in many areas of research.



Management Of Animal Care And Use Programs In Research Education And Testing


Management Of Animal Care And Use Programs In Research Education And Testing
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Author : Robert H. Weichbrod
language : en
Publisher: CRC Press
Release Date : 2017-09-07

Management Of Animal Care And Use Programs In Research Education And Testing written by Robert H. Weichbrod and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-07 with Medical categories.


AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).



Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research


Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2003-08-22

Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08-22 with Science categories.


Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.



The Laboratory Mouse


The Laboratory Mouse
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Author : Peggy J. Danneman
language : en
Publisher: CRC Press
Release Date : 2012-09-25

The Laboratory Mouse written by Peggy J. Danneman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-25 with Medical categories.


Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a



Genetics And Probability In Animal Breeding Experiments


Genetics And Probability In Animal Breeding Experiments
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Author : Earl Leroy Green
language : en
Publisher: Oxford University Press, USA
Release Date : 1981

Genetics And Probability In Animal Breeding Experiments written by Earl Leroy Green and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Science categories.