Oncolytic Viruses
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Oncolytic Viruses Genetically Engineering The Future Of Cancer Therapy
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Author : Benjamin Gesundheit
language : en
Publisher: Frontiers Media SA
Release Date : 2016-11-22
Oncolytic Viruses Genetically Engineering The Future Of Cancer Therapy written by Benjamin Gesundheit and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-22 with categories.
The ability to genetically engineer oncolytic viruses in order to minimize side effects and improve the selective targeting of tumor cells has opened up novel opportunities for treating cancer. Understanding the mechanisms involved and the complex interaction between the viruses and the immune system will undoubtedly help guide the development of new strategies. Theranostic biomarkers to monitor these therapies in clinical trials serve an important need in this innovative field and demand further research.
Understanding Viruses
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Author : Teri Shors
language : en
Publisher: Jones & Bartlett Publishers
Release Date : 2013
Understanding Viruses written by Teri Shors and has been published by Jones & Bartlett Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
The ideal text for undergraduate students majoring in biology, microbiology, medical technology, or pre-med, the Second Edition of Understanding Viruses provides a balanced approach to this fascinating discipline, combining the molecular, clinical, and historical aspects of virology. Updated throughout to keep pace with this fast-paced field, the text provides a strong, comprehensive introduction to human viral diseases. New material on molecular virology as well as new virus families presented coupled with chapters on viral diseases of animals; the history of clinical trials, gene therapy, and xenotranplantation; prions and viroids; plant viruses; and bacteriophages add to the scope of the text. Chapters discussing specific viral diseases weave in an epidemiological and global perspective and include treatment and prevention information. Contemporary case studies, Refresher Boxes, and Virus Files engage students in the learning process. With a wealth of student and instructor support tools, Understanding Viruses is an accessible, exciting, and engaging text for your virology course.
Stem Cell Biology In Health And Disease
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Author : Thomas Dittmar
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-13
Stem Cell Biology In Health And Disease written by Thomas Dittmar and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-13 with Medical categories.
Stem Cell Biology in Health and Disease presents an up-to-date overview about the dual role of stem cells in health and disease. The Editors have drawn together an international team of experts providing chapters which, in this fully-illustrated volume, discuss: - the controversial debate on the great expectations concerning stem cell based regeneration therapies raised by the pluripotency of various stem cells. - the advantages and concerns about embryonic stem cells (ES cells), induced pluripotent stem cells (iPS cells) and adult stem cells, such as bone marrow-derived stem cells (BMDCs). - the type of stem cells, which has become of interest in the past decade, namely so-called cancer stem cells (CSCs). CSCs are now in the focus of cancer research since the eradication of tumour initiating cells would raise the changes of definitely cure cancer. Professor Dittmar and Professor Zänker have edited a must-read book for researchers and professionals working in the field of regenerative medicine and/or cancer.
Gene And Cell Therapy
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Author : Nancy Smyth Templeton
language : en
Publisher: CRC Press
Release Date : 2008-10-06
Gene And Cell Therapy written by Nancy Smyth Templeton and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-06 with Science categories.
Since the publication of the second edition of this book in 2004, gene therapy and cell therapy clinical trials have yielded some remarkable successes and some disappointing failures. Now in its third edition, Gene and Cell Therapy: Therapeutic Mechanisms and Strategies assembles many of the new technical advances in gene delivery, clinical applications, and new approaches to the regulation and modification of gene expression. New Topics Covered in this Edition: Gene and Cell Therapies for Diabetes and Cardiovascular Diseases Clinical Trials Human Embryonic Stem Cells Tissue Engineering Combined with Cell Therapies Novel Polymers Relevant Nanotechnologies SiRNA Therapeutic Strategies Dendrimer Technologies Comprised of contributions from international experts, this book begins with a discussion of delivery systems and therapeutic strategies, exploring retroviral vectors and adenovirus vectors, as well as other therapeutic strategies. The middle section focuses on gene expression and detection, followed by an examination of various therapeutic strategies for individual diseases, including hematopoietic disorders, cardiovascular conditions, cancer, diabetes, cystic fibrosis, neurological disorders, and childhood-onset blindness. The final section discusses recent clinical trials and regulatory issues surrounding the new technology. This compendium is assembled by noted molecular biologist and biochemist Nancy Smyth Templeton. Baylor College of Medicine and several other institutions have used Dr. Templeton’s non-viral therapeutics in clinical trials for the treatment of lung, breast, head and neck, and pancreatic cancers, as well as Hepatitis B and C. She continues to work at the forefront of research in gene and cell therapies. Her contributions, as well as those contained in this volume, are sure to advance the state of the art of these revolutionary life-saving technologies.
Cancer Causing Viruses And Their Inhibitors
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Author : Satya Prakash Gupta
language : en
Publisher: CRC Press
Release Date : 2014-05-16
Cancer Causing Viruses And Their Inhibitors written by Satya Prakash Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-16 with Medical categories.
Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who di
Virus Bioinformatics
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Author : Dmitrij Frishman
language : en
Publisher: CRC Press
Release Date : 2021-08-18
Virus Bioinformatics written by Dmitrij Frishman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-18 with Science categories.
Viruses are the most numerous and deadliest biological entities on the planet, infecting all types of living organisms—from bacteria to human beings. The constantly expanding repertoire of experimental approaches available to study viruses includes both low-throughput techniques, such as imaging and 3D structure determination, and modern OMICS technologies, such as genome sequencing, ribosomal profiling, and RNA structure probing. Bioinformatics of viruses faces significant challenges due to their seemingly unlimited diversity, unusual lifestyle, great variety of replication strategies, compact genome organization, and rapid rate of evolution. At the same time, it also has the potential to deliver decisive clues for developing vaccines and medications against dangerous viral outbreaks, such as the recent coronavirus pandemics. Virus Bioinformatics reviews state-of-the-art bioinformatics algorithms and recent advances in data analysis in virology. FEATURES Contributions from leading international experts in the field Discusses open questions and urgent needs Covers a broad spectrum of topics, including evolution, structure, and function of viruses, including coronaviruses The book will be of great interest to computational biologists wishing to venture into the rapidly advancing field of virus bioinformatics as well as to virologists interested in acquiring basic bioinformatics skills to support their wet lab work.
Oncoimmunology
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Author : Laurence Zitvogel
language : en
Publisher: Springer
Release Date : 2017-12-13
Oncoimmunology written by Laurence Zitvogel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-13 with Medical categories.
In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.
Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 2008
Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Cancer categories.
Cancer Regional Therapy
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Author : Yuman Fong
language : en
Publisher: Springer Nature
Release Date : 2019-12-10
Cancer Regional Therapy written by Yuman Fong and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-10 with Medical categories.
This book is a state-of-the-art overview of cancer regional therapy (CRT) for the surgeons and interventional radiologists active in CRT development and research. The goals of this book are 1) to review the theory and practice of cancer regional therapies including pharmacology, devices, techniques, and workflow, 2) illustrate the most common procedures performed in the interventional and operating rooms, and 3) discuss data supporting use of CRT. This is meant to be a definitive text on the theory and practice of CRT. It begins with a summary of the history, technical principles that underlie regional therapy. The following parts discuss current data and practice in peritoneal, liver, limb, pleural and other sites. Included in the practice are considerations of workflow and financial issues revolving around CRT. Novel techniques and therapies under investigation are presented to inform the direction of the field. Cancer Regional Therapy summarizes the history, current technology, common procedures, and future prospects in this field and includes procedures from many surgical and interventional radiologic disciplines.
Textbook Of General Virology
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Author : Sachin Kumar
language : en
Publisher: CRC Press
Release Date : 2025-03-31
Textbook Of General Virology written by Sachin Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-31 with Science categories.
This book is an introductory text that presents fundamental knowledge and recent advances in virology. It provides comprehensive coverage of different aspects like classification, structure, emerging viruses, cancer-causing viruses, and viral vaccines. It covers the basic biology of virus existence, evolution, and reoccurrence. It also incorporates the fundamentals of biophysical and biochemical aspects of viral replication. The book discusses important topics such as immunity to viral infections, bacteriophages, and techniques used in virology. The Textbook of General Virology is meant for undergraduate and postgraduate students of microbiology, immunology, genetics, and medicine. Key Features: Discusses introductory and foundational knowledge of viruses for students of life sciences and medicine Covers the virus history, diversity of its infection strategy, and classification Summarizes the characteristics of different viruses on the basis of nucleic acid genome type Describes the biology of RNA and DNA viruses and their effect on cell growth control in animals and humans after infection Reviews topics like immunity to viruses and viral vaccines