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Opioider


Opioider
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Opioider


Opioider
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Author : Kalla Wikipedia
language : en
Publisher: University-Press.org
Release Date : 2013-09

Opioider written by Kalla Wikipedia and has been published by University-Press.org this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09 with categories.


Kalla: Wikipedia. Sidor: 41. Kapitlen: Kodein, Metadon, Tramadol, Morfin, Heroin, Dextropropoxifen, Opioid, Buprenorfin, Fentanyl, Dextrometorfan, Naltrexon, Fencyklidin, Alfentanil, Oxikodon, Fenylalanin, Petidin, Allylprodin, Anileridin, Alfametyltiofentanyl, Metadol, Etylmorfin, Pentazocin, Sufentanil, Ketobemidon, Drotebanol, Nikokodein, O-desmetyltramadol, Hydromorfon, Nikodikodein, Etorfin, Levometorfan, Oximorfon, Racemetorfan, Tebain, Naloxon, Fenazocin, Hydrokodon, Salvinorin A, Moramid, Proheptazin, Dihydrokodein, Morfin-N-oxid, Diampromid, Betahydroxifentanyl, Besitramid, Loperamid, Desomorfin, Difenoxylat, Karfentanil, Levofenacylmorfan, Fenoperidin, Etylmetyltiambuten, Normorfin, Etoxeridin, Bensylmorfin, Moramidintermediat, Dietyltiambuten, Piritramid, Dimetyltiambuten, Furetidin, Fenkamfamin, Hydromorfinol, Alfaprodin, Meprodin, Betaprodin, Morferidin, Nikomorfin, Dipipanon, Etonitazen, Fenomorfan, Piminodin, Fenadoxon, Trimeperidin, Klonitazen, Dioxafetylbutyrat, Difenoxin, Dihydromorfin, Properidin, Propiram, Tilidin, Bensetidin, Myrofin, Metazocin, Dimenoxadol, Levorfanol, Lefetamin, Metopon, Normetadon, Norlevorfanol, Metyldesorfin, Isometadon, Alfacetylmetadol, Norpipanon, Durogesic, Actiq, Morfinan. Utdrag: Heroin eller diacetylmorfin, ar ett narkotikaklassat preparat som kemiskt ar beslaktat med, och utvinns av, morfin. Till skillnad fran morfin har heroin en hogre fettloslighet, vilket gor att heroinmolekylen (diacetylmorfin) snabbare passerar blod-hjarnbarriaren och ger typiska effekter, som mycket kraftig eufori, samt apati, forstoppning, illamaende och eventuell uppkastning, gashud somnloshet, mios. Under ruset, som pagar under



Opioids Ii


Opioids Ii
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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Opioids Ii written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more than 60 chapters experts present state-of-the-art reviews of this fascinating field, the topics ranging from molecular biology to clinical applications. Part I covers the multiplicity of opioid receptors, the chemistry of opiates and opioid peptides as well as the neurophysiology of opioids. Part II reviews a broad spectrum of physiological and behavioral functions and pharmacological actions of opioids, together with their neuroendocrinology, opioid tolerance and dependence, concluding with pathophysiological aspects and clinical use.



The Opiate Receptors


The Opiate Receptors
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Author : Gavril W. Pasternak
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-30

The Opiate Receptors written by Gavril W. Pasternak and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-30 with Medical categories.


This new edition covers the latest knowledge on opiate receptors and related receptor subtypes. It discusses many topics pertaining to the unique integrated approach of correlating the biochemical, physiological and pharmacological aspects of opiate reaction.



Opioid Peptides


Opioid Peptides
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Author : Rao S. Rapaka
language : en
Publisher:
Release Date : 1986

Opioid Peptides written by Rao S. Rapaka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Endorphins categories.


"This monograph is based upon papers and discussion from the technical review on the medicinal chemistry and molecular pharmacology of opioid peptides and the opiates which took place on September 4-6, 1984, at Bethesda, Maryland. The meeting was sponsored by the Office of Science and the Division of Preclinical Research, National Institute on Drug Abuse. The papers on molecular pharmacology, biosynthesis, and analysis of opioid peptides are presented in this volume. Those on the medical chemistry of opioid peptides appear in NIDA Research Monograph 69" [entitled Opioid peptides : medicinal chemistry] -- page iv.



Opioid Analgesics


Opioid Analgesics
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Author : A.F. Casy
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Opioid Analgesics written by A.F. Casy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.


The rapidly burgeoning research of the past two decades on agonist-antagonist analgesics and opioid receptors makes this exhaustive review of opioid anal gesics particularly relevant and timely. After an introductory chapter the additional 12 chapters begin logically with morphine and congeners (4- epoxymorphinans) and end with opioid receptors. All principal chemical types of centrally acting analgesics (including endogenous opioid-like substances) and their antagonists as well as the mixed agonist-antagonists are treated thoroughly, although not always (and for good reason) in historical (chrono logical) order. A chapter on miscellaneous types (atypical structures for the most part) includes the benzimidazoles (etonitazene), aminotetralins (dezocine), tetrahydroisoquinolines (methopholine), and so on. Important aspects and correlations of chemistry, pharmacology, and biochemistry are discussed in depth. Literature citations are numerous. For educators, practicing laboratory scientists, and physicians, this scholarly review by two authors well of opioid analgesics versed in the chemistry, pharmacology, and biochemistry will be informative, stimulating, and thought-provoking. Everette L. May Medical College of Virginia Richmond, VA 23298 v Preface The history of opium predates the written word, although knowledge of its constituents dates back less than 200 years. Over the centuries its popularity for the relief of pain has waxed and waned, until today the opiates are widely recognized as excellent analgesics but with disadvantages that have impaired their use seriously. There is a clear need for a potent analgesic with minimal effects on the respiratory centers and gastrointestinal tract and preferably devoid of dependence liability.



The Opiate Receptors


The Opiate Receptors
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Author : Gavril Pasternak
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

The Opiate Receptors written by Gavril Pasternak and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.


The growth of the opiate field over the past decade has been enor mous. Initial interest focused upon the strategic clinical impor tance of morphine and its analogs, but the discovery of the enkephalins and the other endogenous opioid peptides with their widespread actions within brain has expanded the field to investi gators in almost all areas of neuroscience as well as pharmacol ogy. Unfortunately, this field of research with its vast literature has become progressively more complex. The receptors are no longer limited to opiates, but include many subtypes selective for the opioid peptides. Indeed, they might be better termed opioid, rather than opiate, receptors. Many controversies have emerged and been settled; others remain. Early studies must now be inter preted on the basis of current information. Thousands of papers examining various aspects of opiates and the endogenous opioids present separate pieces of a large puzzle. The goal of this volume is to put the pieces together to give a coherent overview of opiate receptor pharmacology and to provide insights into both the mo lecular and classical pharmacology of opiates and the opioid pep tides. The issue of multiple classes of opiate and opioid peptide re ceptors and their importance in understanding mechanisms of ac tion provides the major focus of the book. The study of opiates and opioid peptides provides a unique research opportunity in the neuropharmacology of drug receptors.



A Time Release History Of The Opioid Epidemic


A Time Release History Of The Opioid Epidemic
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Author : J.N. Campbell
language : en
Publisher: Springer
Release Date : 2018-06-09

A Time Release History Of The Opioid Epidemic written by J.N. Campbell and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-09 with Science categories.


This Brief takes the reader on a chemical journey by following the history for over two centuries of how an opiate became an opioid, thus spawning an empire and a series of crises. These imperfect resemblances of alkaloids are both natural and synthetic substances that, particularly in America, are continually part of a growing concern about overuse. This seemed an inviting prospect for those in pain, but as the ubiquitous media coverage continues to lay bare, the levels of abuse point to the fact that perhaps an epidemic is upon us, if not a culture war. Seeking answers to how and why this addiction crisis transpired over two hundred years of long development, this Brief examines the role that the chemistry laboratory played in turning patients into consumers. By utilizing a host of diverse sources, this Brief seeks to trace the design and the production of opioids and their antecedents over the past two centuries. From the isolation and development of the first alkaloids with morphine that relieved pain within the home and on the battlefield, to the widespread use of nostrums and the addiction crisis that ensued, to the dissemination of drugs by what became known as Big Pharma after the World Wars; and finally, to competition from home-made pharmaceuticals, the progenitor was always, in some form, a type of chemistry lab. At times, the laboratory pressed science to think deeply about society's maladies, such as curing disease and alleviating pain, in order to look for new opportunities in the name of progress. Despite the best intentions opioids have created a paradox of pain as they were manipulated by creating relief with synthetic precision and influencing a dystopian vision. Thus, influence came in many forms, from governments, from the medical community, and from the entrepreneurial aspirations of the general populace. For better, but mostly for worse, all played a role in changing forever the trajectory of what started with the isolation of a compound in Germany. Combining chemistry and history in a rousing new long-form narrative that even broadens the definition of a laboratory, the origins and future of this complicated topic are carefully examined.



Chemistry Of Opioids


Chemistry Of Opioids
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Author : Hiroshi Nagase
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-19

Chemistry Of Opioids written by Hiroshi Nagase and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-19 with Science categories.


Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Trials; by H. Nagase and H. Fujii * Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea * 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions; by J. W. Lewis and S. M. Husbands * Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?; by S. N. Calderon * Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects; by K. M. Lovell, K. M. Prevatt-Smith, A. Lozama and T. E. Prisinzano * Synthesis of Novel Basic Skeletons Derived from Naltrexone; by H. Nagase and H. Fujii * Twin and Triplet Drugs in Opioid Research; by H. Fujii * 3D-Pharmacophore Identification for κ-Opioid Agonists Using Ligand-Based Drug-Design Techniques; by N. Yamaotsu and S. Hirono



Opioid Peptides


Opioid Peptides
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Author : Rao S. Rapaka
language : en
Publisher:
Release Date : 1986

Opioid Peptides written by Rao S. Rapaka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Analgesics categories.




Opioids


Opioids
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Author : George F. Koob
language : en
Publisher: Academic Press
Release Date : 2023-05-31

Opioids written by George F. Koob and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-31 with Psychology categories.


A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in opioid addiction Includes Neurocircuitry, Cellular and Molecular neurobiological mechanisms of opioid addiction Defines opioid abuse and addiction potential, including biological tolerance