Optimal Experimental Design For Non Linear Models
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Optimal Experimental Design For Non Linear Models
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Author : Christos P. Kitsos
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-09
Optimal Experimental Design For Non Linear Models written by Christos P. Kitsos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-09 with Mathematics categories.
This book tackles the Optimal Non-Linear Experimental Design problem from an applications perspective. At the same time it offers extensive mathematical background material that avoids technicalities, making it accessible to non-mathematicians: Biologists, Medical Statisticians, Sociologists, Engineers, Chemists and Physicists will find new approaches to conducting their experiments. The book is recommended for Graduate Students and Researchers.
Optimal Design For Nonlinear Response Models
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Author : Valerii V. Fedorov
language : en
Publisher: CRC Press
Release Date : 2013-07-15
Optimal Design For Nonlinear Response Models written by Valerii V. Fedorov and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-15 with Mathematics categories.
Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors’ many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of the key ideas, using linear models as examples. Applying the linearization in the parameter space, it then covers nonlinear models and locally optimal designs as well as minimax, optimal on average, and Bayesian designs. The authors also discuss adaptive designs, focusing on procedures with non-informative stopping. The common goals of experimental design—such as reducing costs, supporting efficient decision making, and gaining maximum information under various constraints—are often the same across diverse applied areas. Ethical and regulatory aspects play a much more prominent role in biological, medical, and pharmaceutical research. The authors address all of these issues through many examples in the book.
Optimal Design Of Experiments
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Author : Friedrich Pukelsheim
language : en
Publisher: SIAM
Release Date : 1993-01-01
Optimal Design Of Experiments written by Friedrich Pukelsheim and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-01-01 with Mathematics categories.
Optimal Design of Experiments offers a rare blend of linear algebra, convex analysis, and statistics. The optimal design for statistical experiments is first formulated as a concave matrix optimization problem. Using tools from convex analysis, the problem is solved generally for a wide class of optimality criteria such as D-, A-, or E-optimality. The book then offers a complementary approach that calls for the study of the symmetry properties of the design problem, exploiting such notions as matrix majorization and the Kiefer information matrix ordering. The results are illustrated with optimal designs for polynomial fit models, Bayes designs, balanced incomplete block designs, exchangeable designs on the cube, rotatable designs on the sphere, and many other examples. Since the book's initial publication in 1993, readers have used its methods to derive optimal designs on the circle, optimal mixture designs, and optimal designs in other statistical models. Using local linearization techniques, the methods described in the book prove useful even for nonlinear cases, in identifying practical designs of experiments. Audience: anyone involved in planning statistical experiments, including mathematical statisticians, applied statisticians, and mathematicians interested in matrix optimization problems.
Optimal Experimental Design For Non Linear Models
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Author : Christos P. Kitsos
language : en
Publisher:
Release Date : 2014-01-31
Optimal Experimental Design For Non Linear Models written by Christos P. Kitsos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-31 with categories.
Design Of Experiments In Nonlinear Models
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Author : Luc Pronzato
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-10
Design Of Experiments In Nonlinear Models written by Luc Pronzato and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-10 with Medical categories.
Design of Experiments in Nonlinear Models: Asymptotic Normality, Optimality Criteria and Small-Sample Properties provides a comprehensive coverage of the various aspects of experimental design for nonlinear models. The book contains original contributions to the theory of optimal experiments that will interest students and researchers in the field. Practitionners motivated by applications will find valuable tools to help them designing their experiments. The first three chapters expose the connections between the asymptotic properties of estimators in parametric models and experimental design, with more emphasis than usual on some particular aspects like the estimation of a nonlinear function of the model parameters, models with heteroscedastic errors, etc. Classical optimality criteria based on those asymptotic properties are then presented thoroughly in a special chapter. Three chapters are dedicated to specific issues raised by nonlinear models. The construction of design criteria derived from non-asymptotic considerations (small-sample situation) is detailed. The connection between design and identifiability/estimability issues is investigated. Several approaches are presented to face the problem caused by the dependence of an optimal design on the value of the parameters to be estimated. A survey of algorithmic methods for the construction of optimal designs is provided.
Optimal Experimental Design
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Author : Jesús López-Fidalgo
language : en
Publisher: Springer Nature
Release Date : 2023-09-12
Optimal Experimental Design written by Jesús López-Fidalgo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-12 with Mathematics categories.
This textbook provides a concise introduction to optimal experimental design and efficiently prepares the reader for research in the area. It presents the common concepts and techniques for linear and nonlinear models as well as Bayesian optimal designs. The last two chapters are devoted to particular themes of interest, including recent developments and hot topics in optimal experimental design, and real-world applications. Numerous examples and exercises are included, some of them with solutions or hints, as well as references to the existing software for computing designs. The book is primarily intended for graduate students and young researchers in statistics and applied mathematics who are new to the field of optimal experimental design. Given the applications and the way concepts and results are introduced, parts of the text will also appeal to engineers and other applied researchers.
Optimal Design Of Experiments
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Author : Peter Goos
language : en
Publisher: John Wiley & Sons
Release Date : 2011-06-28
Optimal Design Of Experiments written by Peter Goos and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Science categories.
"This is an engaging and informative book on the modern practice of experimental design. The authors' writing style is entertaining, the consulting dialogs are extremely enjoyable, and the technical material is presented brilliantly but not overwhelmingly. The book is a joy to read. Everyone who practices or teaches DOE should read this book." - Douglas C. Montgomery, Regents Professor, Department of Industrial Engineering, Arizona State University "It's been said: 'Design for the experiment, don't experiment for the design.' This book ably demonstrates this notion by showing how tailor-made, optimal designs can be effectively employed to meet a client's actual needs. It should be required reading for anyone interested in using the design of experiments in industrial settings." —Christopher J. Nachtsheim, Frank A Donaldson Chair in Operations Management, Carlson School of Management, University of Minnesota This book demonstrates the utility of the computer-aided optimal design approach using real industrial examples. These examples address questions such as the following: How can I do screening inexpensively if I have dozens of factors to investigate? What can I do if I have day-to-day variability and I can only perform 3 runs a day? How can I do RSM cost effectively if I have categorical factors? How can I design and analyze experiments when there is a factor that can only be changed a few times over the study? How can I include both ingredients in a mixture and processing factors in the same study? How can I design an experiment if there are many factor combinations that are impossible to run? How can I make sure that a time trend due to warming up of equipment does not affect the conclusions from a study? How can I take into account batch information in when designing experiments involving multiple batches? How can I add runs to a botched experiment to resolve ambiguities? While answering these questions the book also shows how to evaluate and compare designs. This allows researchers to make sensible trade-offs between the cost of experimentation and the amount of information they obtain.
Optimal Mixture Experiments
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Author : B.K. Sinha
language : en
Publisher: Springer
Release Date : 2014-05-24
Optimal Mixture Experiments written by B.K. Sinha and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-24 with Mathematics categories.
The book dwells mainly on the optimality aspects of mixture designs. As mixture models are a special case of regression models, a general discussion on regression designs has been presented, which includes topics like continuous designs, de la Garza phenomenon, Loewner order domination, Equivalence theorems for different optimality criteria and standard optimality results for single variable polynomial regression and multivariate linear and quadratic regression models. This is followed by a review of the available literature on estimation of parameters in mixture models. Based on recent research findings, the volume also introduces optimal mixture designs for estimation of optimum mixing proportions in different mixture models, which include Scheffé’s quadratic model, Darroch-Waller model, log- contrast model, mixture-amount models, random coefficient models and multi-response model. Robust mixture designs and mixture designs in blocks have been also reviewed. Moreover, some applications of mixture designs in areas like agriculture, pharmaceutics and food and beverages have been presented. Familiarity with the basic concepts of design and analysis of experiments, along with the concept of optimality criteria are desirable prerequisites for a clear understanding of the book. It is likely to be helpful to both theoreticians and practitioners working in the area of mixture experiments.
Linear Models For Optimal Test Design
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Author : Wim J. van der Linden
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-08-09
Linear Models For Optimal Test Design written by Wim J. van der Linden and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-09 with Education categories.
Wim van der Linden was just given a lifetime achievement award by the National Council on Measurement in Education. There is no one more prominent in the area of educational testing. There are hundreds of computer-based credentialing exams in areas such as accounting, real estate, nursing, and securities, as well as the well-known admissions exams for college, graduate school, medical school, and law school - there is great need on the theory of testing. This book presents the statistical theory and practice behind constructing good tests e.g., how is the first test item selected, how are the next items selected, and when do you have enough items.
Optimal Experimental Design With R
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Author : Dieter Rasch
language : en
Publisher: CRC Press
Release Date : 2011-05-18
Optimal Experimental Design With R written by Dieter Rasch and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-18 with Mathematics categories.
Experimental design is often overlooked in the literature of applied and mathematical statistics: statistics is taught and understood as merely a collection of methods for analyzing data. Consequently, experimenters seldom think about optimal design, including prerequisites such as the necessary sample size needed for a precise answer for an experi