Optimization In Hplc


Optimization In Hplc
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Optimization In Hplc


Optimization In Hplc
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Author : Stavros Kromidas
language : en
Publisher: John Wiley & Sons
Release Date : 2021-11-08

Optimization In Hplc written by Stavros Kromidas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-08 with Science categories.


Learn to maximize the performance of your HPLC or UHPLC system with this resource from leading experts in the field Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes, this comprehensive guide leaves few questions unanswered. Readers will also benefit from the inclusion of: A thorough introduction to optimization strategies for different modes and uses of HPLC, including working under regulatory constraints An exploration of computer aided HPLC optimization, including ChromSwordAuto and Fusion QbD A treatment of current challenges for HPLC users in industry as well as large and small analytical service providers Discussions of current challenges for HPLC equipment suppliers Tailor-made for analytical chemists, chromatographers, pharmacologists, toxicologists, and lab technicians, Optimization in HPLC: Concepts and Strategies will also earn a place on the shelves of analytical laboratories in academia and industry who seek a one-stop reference for optimizing the performance of HPLC systems.



Optimization In Hplc


Optimization In Hplc
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Author : Rudolf E. Kaiser
language : en
Publisher:
Release Date : 1981

Optimization In Hplc written by Rudolf E. Kaiser and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Chromatographic analysis categories.




Techniques For The Automated Optimization Of Hplc Separations


Techniques For The Automated Optimization Of Hplc Separations
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Author : John C. Berridge
language : en
Publisher: John Wiley & Sons
Release Date : 1985

Techniques For The Automated Optimization Of Hplc Separations written by John C. Berridge and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.


High-performance liquid chromatography (HPLC) is now a widely applied and established analytical technique used throughout industry and research. As a tool which the analyst counts as a standard method, it is appropriate that with the increasing management of laboratory methods via microcomputers, the linking of HPLC to such systems should be considered.



Hplc Made To Measure


Hplc Made To Measure
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Author : Stavros Kromidas
language : en
Publisher: John Wiley & Sons
Release Date : 2008-06-05

Hplc Made To Measure written by Stavros Kromidas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-05 with Science categories.


The only topical HPLC book to focus on optimization, this volume addresses the needs of HPLC users who wish to constantly improve their methods, in particular in terms of throughput, accuracy and cost-effectiveness. This handbook features contributions from such bestselling authors as John W. Dolan, Michael McBrien, Veronika R. Meyer, Uwe D. Neue, Lloyd R. Snyder, and Klaus K. Unger, as well as from scientists working for major companies, including Agilent, AstraZeneca, Merck, Schering, Tosoh Biosep, VWR, and Waters. It covers essential aspects of optimization in general, optimization in different LC-modi, hyphenated techniques and computer-aided optimization. The whole is rounded off with a section of user reports.



Optimization Of Hplc And Solid Phase Extraction For Benzodiazepines From Body Fluids


Optimization Of Hplc And Solid Phase Extraction For Benzodiazepines From Body Fluids
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Author : Sahar Tahssin Alkassem
language : en
Publisher:
Release Date : 1993

Optimization Of Hplc And Solid Phase Extraction For Benzodiazepines From Body Fluids written by Sahar Tahssin Alkassem and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with categories.




The Hplc Expert Ii


The Hplc Expert Ii
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Author : Stavros Kromidas
language : en
Publisher: John Wiley & Sons
Release Date : 2017-01-05

The Hplc Expert Ii written by Stavros Kromidas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-05 with Science categories.


How can I use my HPLC/UHPLC equipment in an optimal way, where are the limitations of the technique? These questions are discussed in detail in the sequel of the successful "HPLC Expert" in twelve chapters written by experts in the respective fields. The topics encompass - complementary to the first volume - typical HPLC users' problems and questions such as gradient optimization and hyphenated techniques (LC-MS). An important key aspect of the book is UHPLC: For which analytical problem is it essential, what should be considered? Besides presentation of latest developments directly from the main manufacturers, also UHPLC users and independent service engineers impart their knowledge. Consistent with the target groups, the level is advanced, but the emphasis is on practical applications.



Optimization Of Chromatographic Selectivity


Optimization Of Chromatographic Selectivity
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Author : P.J. Schoenmakers
language : en
Publisher: Elsevier
Release Date : 1986-08-01

Optimization Of Chromatographic Selectivity written by P.J. Schoenmakers and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-08-01 with Science categories.


This is the first detailed description of method development in chromatography - the overall process of which may be summarized as: method selection, phase selection, selectivity optimization, and system optimization. All four aspects receive attention in this book. Chapter 1 gives a short introduction, describes chromatographic theory and nomenclature, and outlines the method development process. Chapter 2 describes guidelines for method selection, and quantitative concepts for characterizing and classifying chromatographic phases. Selective separation methods, from both gas and liquid chromatography are given in Chapter 3; the main parameters of each method are identified and simple, quantitative relations are sought to describe their effects. Criteria by which to judge the quality of separation are discussed in Chapter 4 with clear recommendations for different situations. The specific problems involved in the optimization of chromatographic selectivity are explained in Chapter 5. Optimization procedures, illustrated by examples, are extensively described and compared on the basis of a number of criteria. Suggestions are made both for the application of different procedures and for further research. The optimization of programmed analysis receives special attention in Chapter 6, and the last chapter summarizes the optimization of the chromatographic system, including the optimization of the efficiency, sensitivity and instrumentation. Those involved in developing chromatographic methods or wishing to improve existing methods will value the detailed, structured way in which the subject is presented. Because optimization procedures and criteria are described as elements of a complete optimization package, the book will help the reader to understand, evaluate and select current and future commercial systems.



Scale Up And Optimization In Preparative Chromatography


Scale Up And Optimization In Preparative Chromatography
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Author : Anurag Rathore
language : en
Publisher: CRC Press
Release Date : 2002-09-26

Scale Up And Optimization In Preparative Chromatography written by Anurag Rathore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-26 with Medical categories.


Presenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; d



How To Use Reverse Phase Hplc


How To Use Reverse Phase Hplc
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Author : G. Szepesi
language : en
Publisher: Wiley-VCH
Release Date : 1992-03-18

How To Use Reverse Phase Hplc written by G. Szepesi and has been published by Wiley-VCH this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-03-18 with Science categories.


This important contribution to the scientific community explains various aspects of reverse-phase separations. How to Use Reverse-Phase HPLC surveys the basics of liquid chromatography and summarizes the theoretical aspects of reverse-phase HPLC. Chapters also discuss: the influence of stationary and mobile phases on the efficiency and selectivity of the separations; the use of conventionally used and special reverse phase packings as well as that of masking agents added in the mobile phase; the evaluation of column performance in reverse phase chromatography; the applicability of special methods and techniques in RP-HPLC; the most important practical aspects of phase system optimization; and HPLC method validation summarizing the practical approaches recommended for the design and performance of validation experiments.



Optimization In Hplc


Optimization In Hplc
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Author : Stavros Kromidas
language : en
Publisher: John Wiley & Sons
Release Date : 2021-08-06

Optimization In Hplc written by Stavros Kromidas and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-06 with Science categories.


Learn to maximize the performance of your HPLC or UHPLC system with this resource from leading experts in the field Optimization in HPLC: Concepts and Strategies delivers tried-and-tested strategies for optimizing the performance of HPLC and UHPLC systems for a wide variety of analytical tasks. The book explains how to optimize the different HPLC operation modes for a range of analyses, including small molecules, chiral substances, and biomolecules. It also shows readers when and how computational tools may be used to optimize performance. The practice-oriented text describes common challenges faced by users and developers of HPLC and UHPLC systems, as well as how those challenges can be overcome. Written for first-time and experienced users of HPLC technology and keeping pace with recent developments in HPLC instrumentation and operation modes, this comprehensive guide leaves few questions unanswered. Readers will also benefit from the inclusion of: A thorough introduction to optimization strategies for different modes and uses of HPLC, including working under regulatory constraints An exploration of computer aided HPLC optimization, including ChromSwordAuto and Fusion QbD A treatment of current challenges for HPLC users in industry as well as large and small analytical service providers Discussions of current challenges for HPLC equipment suppliers Tailor-made for analytical chemists, chromatographers, pharmacologists, toxicologists, and lab technicians, Optimization in HPLC: Concepts and Strategies will also earn a place on the shelves of analytical laboratories in academia and industry who seek a one-stop reference for optimizing the performance of HPLC systems.