Optimization Of Trustworthy Biomolecular Quantitative Analysis Using Cyber Physical Microfluidic Platforms

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Optimization Of Trustworthy Biomolecular Quantitative Analysis Using Cyber Physical Microfluidic Platforms
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Author : Mohamed Ibrahim
language : en
Publisher: CRC Press
Release Date : 2020-05-31
Optimization Of Trustworthy Biomolecular Quantitative Analysis Using Cyber Physical Microfluidic Platforms written by Mohamed Ibrahim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-31 with Technology & Engineering categories.
A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Optimization Of Trustworthy Biomolecular Quantitative Analysis Using Cyber Physical Microfluidic Platforms
DOWNLOAD
Author : Mohamed Ibrahim
language : en
Publisher: CRC Press
Release Date : 2020-05-31
Optimization Of Trustworthy Biomolecular Quantitative Analysis Using Cyber Physical Microfluidic Platforms written by Mohamed Ibrahim and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-31 with Technology & Engineering categories.
A microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Digital Microfluidic Biochips
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Author : Krishnendu Chakrabarty
language : en
Publisher: CRC Press
Release Date : 2018-10-03
Digital Microfluidic Biochips written by Krishnendu Chakrabarty and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-03 with Technology & Engineering categories.
Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.
Biochip Technology
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Author : Jing Cheng
language : en
Publisher: CRC Press
Release Date : 2003-09-02
Biochip Technology written by Jing Cheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-02 with Science categories.
Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.
5th International Conference On Biomedical Engineering In Vietnam
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Author : Vo Van Toi
language : en
Publisher: Springer
Release Date : 2014-11-18
5th International Conference On Biomedical Engineering In Vietnam written by Vo Van Toi and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-18 with Technology & Engineering categories.
This volume presents the proceedings of the Fifth International Conference on the Development of Biomedical Engineering in Vietnam which was held from June 16-18, 2014 in Ho Chi Minh City. The volume reflects the progress of Biomedical Engineering and discusses problems and solutions. I aims identifying new challenges, and shaping future directions for research in biomedical engineering fields including medical instrumentation, bioinformatics, biomechanics, medical imaging, drug delivery therapy, regenerative medicine and entrepreneurship in medical devices.
Nanobioengineering
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Author : Bhupinder Singh
language : en
Publisher: CRC Press
Release Date : 2018-11-02
Nanobioengineering written by Bhupinder Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-02 with Science categories.
The objective of this book is to provide the fundamental comprehension of a broad range of topics in an integrated volume such that readership hailing from diverse disciplines can rapidly acquire the necessary background for applying it in pertinent research and development field.
Nanotechnology Enabled Sensors
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Author : Kourosh Kalantar-zadeh
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-09-19
Nanotechnology Enabled Sensors written by Kourosh Kalantar-zadeh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-19 with Technology & Engineering categories.
Nanotechnology provides tools for creating functional materials, devices, and systems by controlling materials at the atomic and molecular scales and making use of novel properties and phenomena. Nanotechnology-enabled sensors find applications in several fields such as health and safety, medicine, process control and diagnostics. This book provides the reader with information on how nanotechnology enabled sensors are currently being used and how they will be used in the future in such diverse fields as communications, building and facilities, medicine, safety, and security, including both homeland defense and military operations.
Waterborne Pathogens
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Author : Majeti Narasimha Vara Prasad
language : en
Publisher: Butterworth-Heinemann
Release Date : 2020-02-07
Waterborne Pathogens written by Majeti Narasimha Vara Prasad and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-07 with Technology & Engineering categories.
Waterborne Pathogens: Detection and Treatment delivers the tools and techniques on how to identify these contaminates and apply the most effective technology for their removal and treatment. Written for researchers and practicing professionals, the book starts with a brief, but readable, review of ubiquitous waterborne pathogens (primarily viruses, bacterial and parasitic protozoa). This coverage is followed by an in-depth discussion of the latest detection and treatment technologies, ranging from Biosensors, to Nanoconjugates, Membrane Based Technologies and Nanotechnology Treatment. Engineers and scientist will find this to be a valuable reference on cutting-edge techniques for suppling safe drinking water across the globe. - Explains the latest research on detection, treatment processes and remediation technologies - Includes sampling, analytical and characterization methods and approaches - Covers cutting-edge research, including Membrane Based Technologies, Nanotechnology Treatment Technologies and Bioremediation Treatment Technologies - Provides background information regarding contamination sources
Omics Technologies And Bio Engineering
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Author : Debmalya Barh
language : en
Publisher: Academic Press
Release Date : 2017-12-01
Omics Technologies And Bio Engineering written by Debmalya Barh and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-01 with Science categories.
Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.
Secure And Trustworthy Cyberphysical Microfluidic Biochips
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Author : Jack Tang
language : en
Publisher: Springer
Release Date : 2019-05-28
Secure And Trustworthy Cyberphysical Microfluidic Biochips written by Jack Tang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-28 with Technology & Engineering categories.
This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.