Organ Development
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Organ Development
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-02-21
Organ Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-21 with Science categories.
Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists. Provides the authority and expertise of leading contributors from an international board of author Presents the latest release in this series Updated release includes the latest information on organ development
Organogenesis From Development To Disease
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Author :
language : en
Publisher:
Release Date : 2017
Organogenesis From Development To Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slight malformations of the organs can cause developmental reprogramming and increase the likelihood of adult onset diseases. The use of experimental animals with genetic mutations that mimic many human conditions has lead to significant scientific advancement of these complex and multifaceted diseases. Furthermore, the utilization of organ culture systems has made for profound insights into the formation of organs. Over recent years, the technology related to molecular profiling and imaging of developing organs has dramatically improved, leading to the identification of subtle genetic and phenotypic alterations. This research topic will focus on the area of organ formation and modeling of human developmental diseases.
Organogenesis In Development
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Author : Peter Koopman
language : en
Publisher:
Release Date : 2010
Organogenesis In Development written by Peter Koopman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. Summarizes the key morphological and cellular events Emphasizes up-to-date research relating to molecular control mechanisms Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease Distils common themes and differences for comparative studies Highlights key remaining questions and sets the agenda for future research
Organ Regeneration Based On Developmental Biology
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Author : Takashi Tsuji
language : en
Publisher: Springer
Release Date : 2017-03-30
Organ Regeneration Based On Developmental Biology written by Takashi Tsuji and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-30 with Science categories.
This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.
Roles Of Skeletal Muscle In Organ Development
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Author : Boris Kablar
language : en
Publisher: Springer Nature
Release Date : 2023-11-13
Roles Of Skeletal Muscle In Organ Development written by Boris Kablar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-13 with Science categories.
Muscle is the only tissue of the four basic types that make the body that can be completely ablated while allowing fetal survival. This book is a result of 25 years of research employing engineered mouse fetuses with no skeletal muscle, a model system that provides a unique opportunity to study body development holistically. A systematic anatomical analysis of such fetuses have shown that several anatomical locations are affected by the absence of the skeletal muscle. This book contains a summarized description of affected anatomical locations such as the alveolar lung epithelium, motor neurons and giant pyramidal cells in the CNS, cholinergic amacrine cells of the retina, and type I hair cells of the crista ampullaris. Several specific bioinformatics and systems biology interventions are also described. The book provides an update on skeletal muscle development, musculoskeletal developmental interactions, trophic relationships between the skeletal muscle and the motor neurons, mechanics of lung development, functional development of two special senses, eye and ear, and finally, skeletal muscle-related reasons for human fetal akinesia and its consequences. This volume in the Advances in Anatomy, Embryology and Cell Biology series stresses the need to think about the developing body and its organs in terms of their mutual interdependence, and to think about diseases, such as pulmonary hypoplasia, amyotrophic lateral sclerosis, or cleft palate, in terms of that interdependence. Directed to developmental biologists, neuroscientists, tissue engineers and health professionals, this book exposes the ideas of interorgan communication and interdependence in homeostasis and disease.
Contemporary Models In Ectodermal Organ Development Maintenance And Regeneration
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Author : Isabelle Miletich
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-12
Contemporary Models In Ectodermal Organ Development Maintenance And Regeneration written by Isabelle Miletich and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-12 with Science categories.
Organogenesis In Development
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Author : Peter Koopman
language : en
Publisher: Academic Press
Release Date : 2010-08-04
Organogenesis In Development written by Peter Koopman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-04 with Science categories.
Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. Summarizes the key morphological and cellular events Emphasizes up-to-date research relating to molecular control mechanisms Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease Distils common themes and differences for comparative studies Highlights key remaining questions and sets the agenda for future research
Regulation Of Organ And Tissue Growth
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Author : Richard J. Goss
language : en
Publisher: Academic Press
Release Date : 2013-09-03
Regulation Of Organ And Tissue Growth written by Richard J. Goss and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-03 with Science categories.
Regulation of Organ and Tissue Growth investigates the mechanisms underlying the regulation of organ and tissue growth. Theories of growth regulation are discussed, along with growth and renewal; factors that influence prenatal brain development; regulation of metabolic and functional properties of muscle; and the role of tension in muscle growth. Heart growth and size in homeotherms are also examined. Comprised of 18 chapters, this book begins with an introduction to two schools of thought that explain the orderly growth of organs and tissues: one contends that the dimensions of body parts are genetically predetermined, while the other holds that the correct size of an organ is a function of the physiological demands impinging on it. Subsequent chapters deal with the regulation of metabolic and functional properties of muscle; the role of tension in muscle growth; the regulation of skeletal growth; the role of erythropoietin in erythropoiesis; and humoral factors in the stimulation and inhibition of lymphopoiesis. The text also considers the postnatal development of the mammalian lung before concluding with a chapter that describes the regulation of ovarian growth by the pineal gland. This monograph will be of interest to students, practitioners, and researchers in biology and physiology.
Organogenesis From Development To Disease
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Author : Sunder Sims-Lucas
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-03
Organogenesis From Development To Disease written by Sunder Sims-Lucas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-03 with categories.
Organogenetic Gene Networks
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Author : James Castelli-Gair Hombría
language : en
Publisher: Springer
Release Date : 2016-08-26
Organogenetic Gene Networks written by James Castelli-Gair Hombría and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-26 with Medical categories.
All animals, including humans, derive from a single cell, which possesses all the genetic instructions needed to define how the animal will look like. However, during development, the millions of cells that derive from the zygote will only select part of this genetic information to give rise to the various organs of the body. The coordination of different cell behaviours during development results in the formation of specialized tissues and organs giving rise to highly adapted animals. This book provides an overview of how this diversification is achieved during organ formation and how it may have evolved. Conserved cellular processes are presented using examples from selected vertebrate and invertebrate species that illustrate how developmental biologists are solving the complex puzzle of organ formation. This volume is aimed to students, researchers and medical doctors alike who want to find a simple but rigorous introduction on how gene networks control organ formation.“div> /div