Roles Of Skeletal Muscle In Organ Development
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Roles Of Skeletal Muscle In Organ Development
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Author : Boris Kablar
language : en
Publisher: Springer Nature
Release Date : 2023-11-13
Roles Of Skeletal Muscle In Organ Development written by Boris Kablar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-13 with Science categories.
Muscle is the only tissue of the four basic types that make the body that can be completely ablated while allowing fetal survival. This book is a result of 25 years of research employing engineered mouse fetuses with no skeletal muscle, a model system that provides a unique opportunity to study body development holistically. A systematic anatomical analysis of such fetuses have shown that several anatomical locations are affected by the absence of the skeletal muscle. This book contains a summarized description of affected anatomical locations such as the alveolar lung epithelium, motor neurons and giant pyramidal cells in the CNS, cholinergic amacrine cells of the retina, and type I hair cells of the crista ampullaris. Several specific bioinformatics and systems biology interventions are also described. The book provides an update on skeletal muscle development, musculoskeletal developmental interactions, trophic relationships between the skeletal muscle and the motor neurons, mechanics of lung development, functional development of two special senses, eye and ear, and finally, skeletal muscle-related reasons for human fetal akinesia and its consequences. This volume in the Advances in Anatomy, Embryology and Cell Biology series stresses the need to think about the developing body and its organs in terms of their mutual interdependence, and to think about diseases, such as pulmonary hypoplasia, amyotrophic lateral sclerosis, or cleft palate, in terms of that interdependence. Directed to developmental biologists, neuroscientists, tissue engineers and health professionals, this book exposes the ideas of interorgan communication and interdependence in homeostasis and disease.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Botulinum Neurotoxins
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Author : Andreas Rummel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-14
Botulinum Neurotoxins written by Andreas Rummel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-14 with Medical categories.
The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.
Anatomy And Physiology
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Author : J. Gordon Betts
language : en
Publisher:
Release Date : 2013-04-25
Anatomy And Physiology written by J. Gordon Betts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-25 with categories.
The Role Of Protein And Amino Acids In Sustaining And Enhancing Performance
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1999-09-15
The Role Of Protein And Amino Acids In Sustaining And Enhancing Performance written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-15 with Technology & Engineering categories.
It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Anatomy Physiology
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Author : Lindsay Biga
language : en
Publisher:
Release Date : 2019-09-26
Anatomy Physiology written by Lindsay Biga and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-26 with categories.
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Skeletal Muscle Circulation
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Author : Ronald J. Korthuis
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011
Skeletal Muscle Circulation written by Ronald J. Korthuis and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References
Designing Foods
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 1988-02-01
Designing Foods written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-02-01 with Medical categories.
This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
Muscle Development In Drosophilia
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Author : Helen Sink
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-02-26
Muscle Development In Drosophilia written by Helen Sink and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-26 with Science categories.
The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.
Muscle Regeneration
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Author : Alexander Mauro
language : en
Publisher: Raven Press (ID)
Release Date : 1979
Muscle Regeneration written by Alexander Mauro and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.