Organogenesis From Development To Disease
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Organogenesis From Development To Disease
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Author : Sunder Sims-Lucas
language : en
Publisher: Frontiers Media SA
Release Date : 2017-11-03
Organogenesis From Development To Disease written by Sunder Sims-Lucas and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-03 with categories.
Organogenesis From Development To Disease
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Author :
language : en
Publisher:
Release Date : 2017
Organogenesis From Development To Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
During embryonic development there are many processes that must take place to produce a viable and healthy fetus. Alterations in the cellular and/or molecular interactions within any particular organ can cause catastrophic defects leading to defective organogenesis and death of the embryo. Even slight malformations of the organs can cause developmental reprogramming and increase the likelihood of adult onset diseases. The use of experimental animals with genetic mutations that mimic many human conditions has lead to significant scientific advancement of these complex and multifaceted diseases. Furthermore, the utilization of organ culture systems has made for profound insights into the formation of organs. Over recent years, the technology related to molecular profiling and imaging of developing organs has dramatically improved, leading to the identification of subtle genetic and phenotypic alterations. This research topic will focus on the area of organ formation and modeling of human developmental diseases.
Organogenesis In Development
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Author : Peter Koopman
language : en
Publisher:
Release Date : 2010
Organogenesis In Development written by Peter Koopman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. Summarizes the key morphological and cellular events Emphasizes up-to-date research relating to molecular control mechanisms Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease Distils common themes and differences for comparative studies Highlights key remaining questions and sets the agenda for future research
Organogenesis In Development
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Author : Peter Koopman
language : en
Publisher: Academic Press
Release Date : 2010-08-04
Organogenesis In Development written by Peter Koopman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-04 with Science categories.
Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. Summarizes the key morphological and cellular events Emphasizes up-to-date research relating to molecular control mechanisms Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease Distils common themes and differences for comparative studies Highlights key remaining questions and sets the agenda for future research
Translational Research And Discovery In Gastroenterology
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Author : Deborah L. Gumucio
language : en
Publisher: John Wiley & Sons
Release Date : 2014-08-11
Translational Research And Discovery In Gastroenterology written by Deborah L. Gumucio and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-11 with Science categories.
Translational Gastroenterology: Organogenesis to Disease bridges the gap between basic and clinical research by providing information on GI (gastrointestinal) organ development discovered through scientific inquiry, alongside clinical observations of acquired and congenital abnormalities. Paired chapters, written from basic science and clinical viewpoints, review the major biological pathways and molecules at work in organ ontogeny and disease. In addition to a comprehensive survey of GI organ development and pathologies, the book also highlights model organisms and new areas of research, with chapters devoted to recent advances in the field of GI stem cell biology, and the potential for tissue engineering of GI organs. The topics covered provide a unique window onto current activity in the field of gastroenterology, fostering enhanced knowledge for developmental biologists as well as for clinical practitioners. Notable features include the following: • Basic science chapters review the molecular and cellular pathways of GI organ development alongside clinical chapters examining organ-based diseases, closing the gap between the bench and the clinic. • Derivative organs – esophagus, stomach, pylorus, small intestine, colon, liver, and pancreas –as well as tissues such as serosa and enteric nervous system that are common to multiple GI organs. • Chapters detailing the use of model organisms – Drosophila, sea urchin, zebrafish, C. elegans, Xenopus – for basic discovery studies are included. • Chapters on GI stem cells and the potential for tissue engineering of the GI organs provide a view to the future of research and therapy in these organs.
Organ Development
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-02-21
Organ Development written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-21 with Science categories.
Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists. Provides the authority and expertise of leading contributors from an international board of author Presents the latest release in this series Updated release includes the latest information on organ development
Medaka
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Author : Kiyoshi Naruse
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-30
Medaka written by Kiyoshi Naruse and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-30 with Science categories.
Oryzias latipes, known as medaka, is a model organism from East Asia. Breeding of this small, egg-laying freshwater teleost fish has long been popular among hobbyists in Japan. Now, as biological science has entered the genome era, the medaka provides significant advantages that make it one of the most valuable vertebrate models: a large collection of spontaneous mutants collected over a century, the presence of highly polymorphic inbred lines established over decades, and a recently completed genome sequence. This book is the first comprehensive monograph to cover a variety of medaka research. It opens with a historical view of medaka, followed by a series of research topics in the four major areas where the medaka is increasingly important: genomics, genetics, and resources; organogenesis and disease models; germ cells, sex determination, and reproduction; and evolution. Readers will find state-of-the-art information on medaka genetics and genomics such as the first isolation of active transposons in vertebrates, the influence of chromatin structure on sequence variation, fine QTL analysis, and versatile mutants as human disease models.
Mouse Development
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Author : Janet Rossant
language : en
Publisher: Gulf Professional Publishing
Release Date : 2002-03
Mouse Development written by Janet Rossant and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-03 with Medical categories.
This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production
Xenopus Models Of Organogenesis And Disease
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Author : John Noel Griffin
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-09
Xenopus Models Of Organogenesis And Disease written by John Noel Griffin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-09 with categories.
Heart Development
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Author : Richard P. Harvey
language : en
Publisher: Gulf Professional Publishing
Release Date : 1999
Heart Development written by Richard P. Harvey and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...