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Organ Tissue Engineering


Organ Tissue Engineering
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Tissue Engineering


Tissue Engineering
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Author : W. Mark Saltzman
language : en
Publisher: Oxford University Press
Release Date : 2004-07-15

Tissue Engineering written by W. Mark Saltzman and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-07-15 with Medical categories.


Tissue or organ transplantation are among the few options available for patients with excessive skin loss, heart or liver failure, and many common ailments, and the demand for replacement tissue greatly exceeds the supply, even before one considers the serious constraints of immunological tissue type matching to avoid immune rejection. Tissue engineering promises to help sidestep constraints on availability and overcome the scientific challenges, with huge medical benefits. This book lays out the principles of tissue engineering. It will be a useful reference work for those associated with this field and as a textbook for specialized courses in the subject. It is a companion volume to Saltzman's OUP book on drug delivery.



Organ Tissue Engineering


Organ Tissue Engineering
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Author : Daniel Eberli
language : en
Publisher: Springer
Release Date : 2021-04-23

Organ Tissue Engineering written by Daniel Eberli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-23 with Technology & Engineering categories.


The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.



Organ Tissue Engineering


Organ Tissue Engineering
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Author : Daniel Eberli
language : en
Publisher: Springer
Release Date : 2021-04-22

Organ Tissue Engineering written by Daniel Eberli and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-22 with Technology & Engineering categories.


The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.



Tissue Engineering Strategies For Organ Regeneration


Tissue Engineering Strategies For Organ Regeneration
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Author : Naznin Sultana
language : en
Publisher: CRC Press
Release Date : 2020-02-04

Tissue Engineering Strategies For Organ Regeneration written by Naznin Sultana and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-04 with Medical categories.


Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies



Tissue Engineering For Tissue And Organ Regeneration


Tissue Engineering For Tissue And Organ Regeneration
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Author : Daniel Eberli
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-08-17

Tissue Engineering For Tissue And Organ Regeneration written by Daniel Eberli and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-17 with Technology & Engineering categories.


Tissue Engineering may offer new treatment alternatives for organ replacement or repair deteriorated organs. Among the clinical applications of Tissue Engineering are the production of artificial skin for burn patients, tissue engineered trachea, cartilage for knee-replacement procedures, urinary bladder replacement, urethra substitutes and cellular therapies for the treatment of urinary incontinence. The Tissue Engineering approach has major advantages over traditional organ transplantation and circumvents the problem of organ shortage. Tissues reconstructed from readily available biopsy material induce only minimal or no immunogenicity when reimplanted in the patient. This book is aimed at anyone interested in the application of Tissue Engineering in different organ systems. It offers insights into a wide variety of strategies applying the principles of Tissue Engineering to tissue and organ regeneration.



Frontiers In Tissue Engineering


Frontiers In Tissue Engineering
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Author : C.W. Patrick
language : en
Publisher: Elsevier
Release Date : 1998-02-20

Frontiers In Tissue Engineering written by C.W. Patrick and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-02-20 with Technology & Engineering categories.


Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.



Principles Of Tissue Engineering


Principles Of Tissue Engineering
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Author : Robert Lanza
language : en
Publisher: Academic Press
Release Date : 2013-10-17

Principles Of Tissue Engineering written by Robert Lanza and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-17 with Technology & Engineering categories.


Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout



Introduction To Tissue Engineering


Introduction To Tissue Engineering
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Author : Ravi Birla
language : en
Publisher: John Wiley & Sons
Release Date : 2014-06-05

Introduction To Tissue Engineering written by Ravi Birla and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-05 with Science categories.


A comprehensive reference and teaching aid on tissue engineering—covering everything from the basics of regenerative medicine to more advanced and forward thinking topics such as the artificial liver, bladder, and trachea Regenerative medicine/tissue engineering is the process of replacing or regenerating human cells, tissues, or organs to restore or establish normal function. It is an incredibly progressive field of medicine that may, in the near future, help with the shortage of life-saving organs available through donation for transplantation. Introduction to Tissue Engineering: Applications and Challenges makes tissue engineering more accessible to undergraduate and graduate students alike. It provides a systematic and logical eight-step process for tissue fabrication. Specific chapters have been dedicated to provide in-depth principles for many of the supporting and enabling technologies during the tissue fabrication process and include biomaterial development and synthesis, bioreactor design, and tissue vascularization. The tissue fabrication process is further illustrated with specific examples for liver, bladder, and trachea. Section-coverage includes an overall introduction of tissue engineering; enabling and supporting technologies; clinical applications; and case studies and future challenges. Introduction to Tissue Engineering: Presents medical applications of stem cells in tissue engineering Deals with the effects of chemical stimulation (growth factors and hormones) Covers current disease pathologies and treatment options (pacemakers, prosthesis) Explains bioengineering, design and fabrication, and critical challenges during tissue fabrication Offers PowerPoint slides for instructors Features case studies and a section on future directions and challenges As pioneering individuals look ahead to the possibility of generating entire organ systems, students may turn to this text for a comprehensive understanding and preparation for the future of regenerative medicine.



Tissue Engineering


Tissue Engineering
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Author : Clemens van Blitterswijk
language : en
Publisher: Academic Press
Release Date : 2014-12-10

Tissue Engineering written by Clemens van Blitterswijk and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-10 with Science categories.


Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering



Biomaterials For Organ And Tissue Regeneration


Biomaterials For Organ And Tissue Regeneration
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Author : Nihal Vrana
language : en
Publisher: Woodhead Publishing
Release Date : 2020-03-20

Biomaterials For Organ And Tissue Regeneration written by Nihal Vrana and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-20 with Medical categories.


Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations