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Organic Nitrates

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Organic Nitrates

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Author : P. Needleman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Organic Nitrates written by P. Needleman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.

Organic Nitrates

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Author : P Needleman
language : en
Publisher:
Release Date : 1975-04-08

Organic Nitrates written by P Needleman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975-04-08 with categories.

Advances In Nitrate Therapy

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Author : Adam Schneeweiss
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Advances In Nitrate Therapy written by Adam Schneeweiss and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

All aspects of nitrate therapy, including conventional and new formulations and delivery systems, are covered in this book. For each drug the formulation, mechanism of action, indications, effects, adverse reactions and special problems are systematically described. The use of nitrates in specific population groups, such as infants, children and the elderly, is dealt with separately. The book is updated, based not only on the world literature but also on the most recent conference presentations, and provides the reader with thorough and practice-oriented coverage.

Organic Nitrates In Energetic Materials Research

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Author : Tobias Lenz
language : en
Publisher:
Release Date : 2023

Organic Nitrates In Energetic Materials Research written by Tobias Lenz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with categories.

120 Years Of Nitrate Therapy Prepared For The Next Millenium

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Author : Thomas F. Lüscher
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-10-12

120 Years Of Nitrate Therapy Prepared For The Next Millenium written by Thomas F. Lüscher and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-12 with Medical categories.

No detailed description available for "120 Years of Nitrate Therapy - Prepared for the Next Millenium".

Nitrite And Nitrate In Human Health And Disease

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Author : Nathan S. Bryan
language : en
Publisher: Humana Press
Release Date : 2017-01-31

Nitrite And Nitrate In Human Health And Disease written by Nathan S. Bryan and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-31 with Medical categories.

This fully revised and updated new edition provides a comprehensive look at nitrite and nitrate and their effect on human health and disease. The first section describes the biochemical analysis of nitrite and nitrate and its role in human physiology. The book then shifts to sources of human exposure of nitrite and nitrate, including environmental and dietary. Finally, the last section discusses nitric oxide-based therapeutics and how nitrite and nitrate biochemistry can be safely harnessed to improve human health. Each chapter provides a balanced, evidence-based view and heavily cites the most recent published literature. They follow a strict chapter format which includes keywords, key points, a conclusion highlighting major findings, and extensive references. The second edition contains new chapters on nitrite and nitrate in age medicine, nitrite and nitrate as a treatment for hypertension, and nitrite and nitrate in exercise performance. Additionally, the editors have expanded the biochemistry section to include chapters on nitrate reducing oral bacteria, nitrite mediated S-Nitrosation, epigenetics and the regulation of nitric oxide, and nitrite control of mitochondrial function. Nitrate and Nitrite in Human Health and Disease, 2e, will be of interest to health professionals, nutritionists, dieticians, biomedical scientists, and food scientists.

Nitrates Updated

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Author : Udho Thadani
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Nitrates Updated written by Udho Thadani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Nitrates remain among the most commonly used therapeutic agents in cardiology. That they can re lieve pain in angina pectoris has been known at least since 1867, when Lauder Brunton described their clinical use. Now, almost 130 years later, we are constantly learning more about their optimal use in anginal syndromes. For example, there is no doubt that nitrate tolerance occurs, but equally no doubt that certain drug dosages help to attenuate such toler ance. Thus, our understanding of nitrate tolerance has been taken further by the advent of new nitrate preparations and by studies at a basic science level. The current intense interest in nitrates has been rekindled by the growing emphasis on the role of the endothelium in the production of nitric oxide, a basic cardiovascular regulator. If nitric oxide is vasodilator and protects the vascular endothelium, then nitrates should also have similar properties. Hence this book starts off with the role of the endothelium and ni trates in vasodilation. Next, the mechanisms of ac tion of nitrates are considered with emphasis on the role of cyclic GMP. The chief limitation to the use of nitrates lies in nitrate tolerance. After carefully looking at all the evidence, the authors of the third chapter conclude that the mechanism is likely to be multifactorial. The mechanism responsible for the tolerance still remains unknown. In vitro tolerance may be due to enhanced production of vascular superoxide [1].

No detailed description available for "Nitroglycerin 9".

Organic Nitrates

Organic Nitrates

Organic Nitrates

Advances In Nitrate Therapy

Organic Nitrates In Energetic Materials Research

120 Years Of Nitrate Therapy Prepared For The Next Millenium

Nitrite And Nitrate In Human Health And Disease

Nitrates Updated

Nitrate Volatile Organic Compounds And Pesticides In Ground Water

Nitrate Therapy Nitrate Tolerance

Nitroglycerin 9

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