Organofluorines
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Organofluorines
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Author : A.H. Neilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-07-03
Organofluorines written by A.H. Neilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-07-03 with Medical categories.
This volume, written by a range of international experts, covers a wide range of topics involving organic fluorine compounds. Each chapter is preceded by a summary and includes extensive illustrations and references. The chapters cover atmospheric chemistry, application of 19F NMR, partition, degradation and transformation, naturally occurring organic fluorine compounds, toxicology of perfluoroalkanes and phosphorofluoridates, and application of aromatic compounds to the elucidation of the mechanism of cytochrome P450.
Organofluorine Chemistry
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Author : Richard D. Chambers
language : en
Publisher: Springer
Release Date : 2003-09-05
Organofluorine Chemistry written by Richard D. Chambers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-05 with Science categories.
The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.
Organofluorine Chemistry
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Author : Richard D. Chambers
language : en
Publisher: Springer
Release Date : 2013-10-03
Organofluorine Chemistry written by Richard D. Chambers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-03 with Science categories.
Fluorine is unique in that it is possible to replace hydrogen by fluorine either singly or multiply,in an organic molecule and,in so-doing create a potentially infinite extension to organic chemistry that is entirely synthetic. The excitement of the chemistry of these systems stems from the unique reactions that ensue and the “special-effects”that introduction of fluorine impart. Indeed,these effects are now exploited in a remarkable array of applications across the whole of the chemical,pharmaceutical,and plant-protection industries,although this is not widely appreciated. In this book, we have gathered authors with immense experience in various aspects of their field and each is a world-authority on the important topics they have described. Some topics, like the use of elemental fluorine, and enzymes in synthesis, are relatively new areas that are rapidly growing. We dedicate the book to a long standing friend,Professor George Olah,in the year of his 70th birthday,in recognition of his massive achievements. Durham,May 1997 Dick Chambers Contents Elemental Fluorine in Organic Chemistry J. Hutchinson and G. Sandford . . . . . . . . . . . . . . . . . . . . . . . . 1 Fluorinated Organometallic Compounds D. J. Burton and L. Lu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Enzymatically Controlled Reactions of Organofluorine Compounds T. Kitazume and T. Yamazaki . . . . . . . . . . . . . . . . . . . . . . . . . 91 Building Block Approaches to Aliphatic Organofluorine Compounds J. M. Percy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131 Electrofluorination of Organic Compounds F. G. Drakesmith . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197 Author Index Volumes 151–193 . . . . . . . . . . . . . . . . . . . . . . . 243 Contents of Volume 192 Organofluorine Chemistry: Fluorinated Alkenes and Reactive Intermediates Volume Editor: R. D. Chambers Nucleophilic Reactions of Fluorinated Alkenes R. D. Chambers and J. F. S.
Organofluorine Chemistry
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Author : Richard D Chambers
language : en
Publisher: Springer
Release Date : 2014-01-15
Organofluorine Chemistry written by Richard D Chambers and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Organofluorine Chemistry
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Author :
language : en
Publisher:
Release Date : 1998
Organofluorine Chemistry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Organofluorines
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Author : A. H. Neilson
language : en
Publisher:
Release Date : 2014-01-15
Organofluorines written by A. H. Neilson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
Organofluorine Chemistry
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Author : Kalman J. Szabo
language : en
Publisher: John Wiley & Sons
Release Date : 2021-03-22
Organofluorine Chemistry written by Kalman J. Szabo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-22 with Science categories.
By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!
Natural Production Of Organohalogen Compounds
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Author : Gordon W. Gribble
language : en
Publisher: Springer
Release Date : 2010-12-07
Natural Production Of Organohalogen Compounds written by Gordon W. Gribble and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-07 with Science categories.
This book summarizes the state-of-the-art knowledge on naturally occurring organohalogens, of which more than 3700 are documented. The chapters cover all aspects of this field, including the structural diversity and sources of organohalogens, the mechanisms for their formation and biodegradation, the clinical use of dichloroacetate, and the synthesis of the powerful anticancer chlorine-containing cryptophycin. Both biogenic and abiogenic sources of organohalogens are treated, the latter of which include volcanic emissions and abiogenic formation in soil. Halogenation in humans, fungi, and in the ocean are covered in separate chapters. Sources and biosynthesis of the relatively rare natural organofluorines are also discussed in this volume. By better understanding of the role nature plays in the area of organohalogens, we can more intelligently regulate the production, use, and disposal of man-made organohalogen compounds.
Organofluorine Compounds In Biology And Medicine
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Author : V Prakash Reddy
language : en
Publisher: Newnes
Release Date : 2015-01-25
Organofluorine Compounds In Biology And Medicine written by V Prakash Reddy and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-25 with Science categories.
Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry
Fluorine And Health
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Author : Alain Tressaud
language : en
Publisher: Elsevier
Release Date : 2008-06-06
Fluorine And Health written by Alain Tressaud and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-06 with Medical categories.
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. New approach of topics involving chemistry, biology and medicinal techniques Transdisciplinar papers on fluoride products Importance of fluoride products in health Updated data on specific topics