Organoselenium Compounds In Biology And Medicine


Organoselenium Compounds In Biology And Medicine
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Organoselenium Compounds In Biology And Medicine


Organoselenium Compounds In Biology And Medicine
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Author : Vimal Kumar Jain
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-10-03

Organoselenium Compounds In Biology And Medicine written by Vimal Kumar Jain and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-03 with Organoselenium compounds categories.


Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.



Selenium In Biology And Medicine


Selenium In Biology And Medicine
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Author : Albrecht Wendel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Selenium In Biology And Medicine written by Albrecht Wendel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


In July, 1988, more than 300 scientists from 29 different countries gathered at Tiibingen, W. Germany, in order to spend 4 days discussing their favourite trace element, selenium. This meeting continued the good tradition of three previous meetings held in Corvallis/Oregon, 1976, in Lubbock/Texas, 1980, and in Beijing/China, in 1984. Incidentally, the University of Tiibingen provided a unique historical background for a Symposium devoted to recent advances in biochemistry, pharmacology, human nutrition and human health; here, the first independent depart ment of Physiological Chemistry in Germany was founded in 1845. Pro fessor H9Ppe-Seyler elucidated here the hemin structure and his student Friedrich Miescher discovered the nucleic acids. This book contains one-half of the oral or poster presentations which were selected before the meeting was held on the basis of a one page abstract. It is the reader who will have to decide whether this time consuming policy of quality assessment was warranted or not.



New Frontiers In Organoselenium Compounds


New Frontiers In Organoselenium Compounds
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Author : Eder João Lenardão
language : en
Publisher: Springer
Release Date : 2018-06-29

New Frontiers In Organoselenium Compounds written by Eder João Lenardão and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-29 with Science categories.


This book presents recent advances in and perspectives on the use of organoselenium compounds, primarily highlighting the new frontiers in the field of Green Chemistry, their therapeutic and biological relevance and new materials. Throughout its 200 pages, readers will find an updated and comprehensive review of new aspects of organoselenium chemistry and biochemistry. Fully referenced and written in an easy to read style, it offers readers a primary resource for including organoselenium derivatives in their projects. This book will be of interest to specialists, students and researchers involved in a broad range of fields, from synthetic green chemistry to medicinal chemistry and the chemistry of natural products. The connection between organoselenium compounds and green chemistry, despite having only recently emerged, is one of the subjects of this book. The first chapter highlights the use of Se-containing molecules as reagents and catalysts in new green protocols to access important organic transformations. The book provides a wealth of examples of bioactive Se-containing molecules, especially focusing on those with potential therapeutic uses. The second chapter focuses on the state of the art concerning the role of organoselenium compounds as antioxidants, GPx mimics, and derivatives endowed with different bioactive properties. “Organoselenium in nature” is the title of the third chapter, which equips readers with essential information on the main natural organoselenium compounds and where they are found. Selected aspects of the metabolism of selenium in plants and microorganisms are also discussed. In closing, the book includes a chapter dedicated to recent advances concerning the nonbonding interactions between organochalcogen compounds. This is currently a hot topic in selenium chemistry and biochemistry, and here readers will find key insights into the chalcogen bond and its role in the biological activity of organoselenium compounds.



Selenium In Biology And Medicine


Selenium In Biology And Medicine
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Author : Albrecht Wendel
language : en
Publisher:
Release Date : 1989

Selenium In Biology And Medicine written by Albrecht Wendel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.




Organoselenium Compounds In Biology And Medicine


Organoselenium Compounds In Biology And Medicine
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Author : Vimal Kumar Jain
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-09-26

Organoselenium Compounds In Biology And Medicine written by Vimal Kumar Jain and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-26 with Science categories.


Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.



Selenium In Biology And Medicine


Selenium In Biology And Medicine
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Author : Albrecht Wendel
language : en
Publisher:
Release Date : 1989-08-16

Selenium In Biology And Medicine written by Albrecht Wendel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-08-16 with categories.


The book gives an account of the most recent development in the understanding of the essential trace element selenium with respect to its role in animals and man. It is divided into five sections covering biochemistry, metabolism, pharmacology, human nutrition and epidemiology, and the interaction of selenium with malignant diseases. Primary new information is available on the synthesis of selenoproteins, metabolic selenium-dependent modulations in animals, and brand-new results on the development of a new, selenium-containing anti-inflammatory drug. For the first time, data from China are presented on the chronic toxicity of selenium in man. A critical appraisal of the debate on the anticarcinogenic effect of selenium is given. Recommended daily intakes of selenium for man and epidemiological data on different countries of the world are reported.



Organoselenium Chemistry


Organoselenium Chemistry
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Author : Brindaban C. Ranu
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-04-20

Organoselenium Chemistry written by Brindaban C. Ranu and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-20 with Science categories.


Organoselenium Chemistry is a unique resource in this branch of organic/organometallic chemistry. The authors give an overview of synthesis strategies, introduce bioactive and environmentally friendly organoselenium compounds and discuss their applications from organic synthesis to the clinic.



Organoselenium Chemistry Between Synthesis And Biochemistry


Organoselenium Chemistry Between Synthesis And Biochemistry
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Author : Claudio Santi
language : en
Publisher: Bentham Science Publishers
Release Date : 2014-04-30

Organoselenium Chemistry Between Synthesis And Biochemistry written by Claudio Santi and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-30 with Science categories.


The use of organoselenium reagents as catalysts is a common thread that runs through the chapters of this book, introducing important aspects of the modern organoselenium chemistry: organocatalysis, green chemistry, bioinspiration, antioxidant activity. The eBook covers the most recent developments in the classical synthetic application of organoselenium reagents such as electrophilic, nucleophilic and free radical reagents. The volume also features a discussion on the synthesis and the synthetic applications of some emerging classes of selenium compounds such as hypervalent selenium species and selenoamides, and also addresses some biological aspects such as the antimicrobial activity of organoselenium derivatives and the biochemistry of selenoproteins. A number of eminent scientists from different research groups were involved in the preparation of the 13 chapters of the book, making Organoselenium Chemistry: Between Synthesis and Biochemistry an excellent reference about selenium chemistry for researchers and graduate students in the field of selenium chemistry.



Atypical Elements In Drug Design


Atypical Elements In Drug Design
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Author : Jacob Schwarz
language : en
Publisher: Springer
Release Date : 2016-04-29

Atypical Elements In Drug Design written by Jacob Schwarz and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-29 with Science categories.


Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.



Organochalcogen Compounds


Organochalcogen Compounds
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Author : Eder João Lenardão
language : en
Publisher: Elsevier
Release Date : 2022-05-17

Organochalcogen Compounds written by Eder João Lenardão and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-17 with Science categories.


Organochalcogen compounds reviews the state of the art in new green protocols involving organochalcogen compounds (Se, S, and Te), including the use of nonconventional reaction media, alternative solvents, and solvent-free protocols to prepare these important compounds. Bringing together several leading researchers in organochalcogen chemistry, it provides an authoritative overview of the current state of the field and compiles recent advances in methodologies for the application of green chemistry principles in compound development. These include the use of organochalcogen compounds as intermediates, catalysts, or target products across a range of applications. The recent developments outlined in in the book reflect the efforts of the researchers in this area to move toward a more sustainable chemistry, giving the book the dual benefit of highlighting the latest developments in the field while also showing how the principles of green chemistry can effectively be included in active research projects. Thus it is a valuable reference for chemists, particularly those working in organic, green, and synthetic chemistry across both academia and industry. Highlights green synthetic methods with potential application in the synthesis of natural compounds or other biologically active scaffolds Explores the chemical modification of natural compounds by insertion of organochalcogen groups for the preparation of boosted bioactive semisynthetic molecules Discuss how redox catalysis and catalysis in flow conditions using eco-friendly oxidant can provide new opportunities for the synthesis of linear ad cyclic derivatives