Origin And Evolution Of New Gene Functions


Origin And Evolution Of New Gene Functions
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Origin And Evolution Of New Gene Functions


Origin And Evolution Of New Gene Functions
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Author : Manyuan Long
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Origin And Evolution Of New Gene Functions written by Manyuan Long and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Although interest in evolutionary novelties can be that these different mechanisms cooperate in the mak traced back to the time of Darwin, the appreciation ing of new genes. In the second phase of new gene evolution, conventional models of new gene evolution, and systematical experimental pursuit of the origin and evolution of new gene functions did not appear for example by gene duplication, held that the muta until the early years of last decade. Since the 1970s, tions fixed in the early stages of the new genes are Susumu Ohno, Walter Gilbert, and others from the assumed to be neutral or nearly neutral. However, it area of evolutionary genetics have made pioneer ef appears that the force of Darwinian positive selection has been detectably strong from the outset in avail forts to elaborate possibilities for major biological mechanisms, for example, gene duplication and exon able population genetic studies of young genes created through the process of exon recombination. This may shuffling, by which new gene functions could arise. However, the problem of new gene evolution did not account for a common phenomenon in phylogenetic catch significant attention among biologists generally analyses of genes with changed functions: the early even recently. One of the reasons was the lack of ex stages of such genes are usually associated with accel perimental or observational systems for investigating erated substitution rates. Nonetheless, a more general factual details of the 'birth' process of new genes.



Genome Evolution


Genome Evolution
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Author : Axel Meyer
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28

Genome Evolution written by Axel Meyer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Science categories.


In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.



Evolution After Gene Duplication


Evolution After Gene Duplication
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Author : Katharina Dittmar
language : en
Publisher: John Wiley & Sons
Release Date : 2011-06-09

Evolution After Gene Duplication written by Katharina Dittmar and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-09 with Science categories.


Gene duplication has long been believed to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. The first book to examine gene duplication across all levels of biological organization, Evolution after Gene Duplication presents a comprehensive picture of the mechanistic process by which gene duplication may have played a role in generating biodiversity. Key Features: Explores comparative genomics, genome evolution studies and analysis of multi-gene families such as Hox, globins, olfactory receptors and MHC (immune system) A complete post-genome treatment of the topic originally covered by Ohno's 1970 classic, this volume extends coverage to include the fate of associated regulatory pathways Taps the significant increase in multi-gene family data that has resulted from comparative genomics Comprehensive coverage that includes opposing theoretical viewpoints, comparative genomics data, theoretical and empirical evidence and the role of bioinformatics in the study of gene duplication This up-to-date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students.



Evolution By Gene Duplication


Evolution By Gene Duplication
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Author : Susumu Ohno
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-11

Evolution By Gene Duplication written by Susumu Ohno and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-11 with Medical categories.


It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.



The Logic Of Chance


The Logic Of Chance
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Author : Eugene V. Koonin
language : en
Publisher: FT Press
Release Date : 2011-06-23

The Logic Of Chance written by Eugene V. Koonin and has been published by FT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-23 with Science categories.


The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and hypotheses on the key aspects of the evolution of life on earth in light of comparative genomics and systems biology. The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept; the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes. "Koonin's account of viral and pre-eukaryotic evolution is undoubtedly up-to-date. His "mega views" of evolution (given what was said above) and his cosmological musings, on the other hand, are interesting reading." Summing Up: Recommended Reprinted with permission from CHOICE, copyright by the American Library Association.



Evolution By Tumor Neofunctionalization


Evolution By Tumor Neofunctionalization
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Author : Andrei P. Kozlov
language : en
Publisher: Academic Press
Release Date : 2014-02-15

Evolution By Tumor Neofunctionalization written by Andrei P. Kozlov and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-15 with Science categories.


Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. Covers the role that tumors might play in evolution. Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more



Gene And Protein Evolution


Gene And Protein Evolution
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Author : Jean-Nicolas Volff
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2007-01-01

Gene And Protein Evolution written by Jean-Nicolas Volff and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Medical categories.


"Our way of understanding evolution has changed completely with the era of genomics, particularly since the emergence of comparative genomics, a discipline allowing the analysis of complete genomes and biological processes over vast periods of time. In this volume, internationally recognized experts present and discuss an update of the evolutionary processes at the onset of organismal diversification and complexity, and review the mechanisms leading to the acquisition of new traits and functions. Different levels of evolution are considered, from internal modules in genes and proteins to interactomes and biological networks, with integration of the influence of both the genomic environment and the ecological context. Particular emphasis will be given to the origin of novel genes and gene functions as well as to the evolutionary impact of the duplication of genetic information, with several chapters devoted to transposable elements. Providing an excellent update on gene and protein evolution, this book will be appreciated by researchers in biology and medicine, biology teachers and anyone interested in evolution and genomics."--Publisher's description.



Gene Sharing And Evolution


Gene Sharing And Evolution
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Author : Joram Piatigorsky
language : en
Publisher: Harvard University Press
Release Date : 2007-02-28

Gene Sharing And Evolution written by Joram Piatigorsky and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-02-28 with Science categories.


In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.



The Concept Of The Gene In Development And Evolution


The Concept Of The Gene In Development And Evolution
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Author : Peter J. Beurton
language : en
Publisher: Cambridge University Press
Release Date : 2000-05-29

The Concept Of The Gene In Development And Evolution written by Peter J. Beurton and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-05-29 with Philosophy categories.


Advances in molecular biological research in the latter half of the twentieth century have made the story of the gene vastly complicated: the more we learn about genes, the less sure we are of what a gene really is. Knowledge about the structure and functioning of genes abounds, but the gene has also become curiously intangible. This collection of essays renews the question: what are genes? Philosophers, historians and working scientists re-evaluate the question in this volume, treating the gene as a focal point of interdisciplinary and international research. It will be of interest to professionals and students in the philosophy and history of science, genetics and molecular biology.



In The Light Of Evolution


In The Light Of Evolution
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Author : National Academy of Sciences
language : en
Publisher: Sackler Colloquium
Release Date : 2007

In The Light Of Evolution written by National Academy of Sciences and has been published by Sackler Colloquium this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.


The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.