Oxidants And Antioxidant Defense Systems
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Oxidants And Antioxidant Defense Systems
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Author : Tilman Grune
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-01-18
Oxidants And Antioxidant Defense Systems written by Tilman Grune and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-18 with Medical categories.
Oxidative stress is one of the major symptoms accompanying physiological functions and numerous diseases. Oxidants and free radicals are connected with diseases such as cancer, diabetes, infectious, cardiovascular and neurodegenerative diseases and also in the aging process itself. Therefore, comprehensive knowledge of the underlying mechanisms of oxidant and free radical production and the defence against this permanent threat to cells is important for the understanding of many physiological and pathophysiological processes. This book overviews the basic mechanisms of oxidant formation and antioxidant defences. In addition, the formation of oxidants and their detoxification, the damage of macromolecules and the major repair and removal systems will be highlighted.
Oxidants Antioxidants And Free Radicals
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Author : Steven Baskin
language : en
Publisher: Routledge
Release Date : 2017-11-01
Oxidants Antioxidants And Free Radicals written by Steven Baskin and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-01 with Medical categories.
This volume collates articles investigating antioxidant, oxidant and free radical research. It examines the role of such research in health and disease, particulary with respect to developing greater understanding about the many interactions between oxidants and antioxidants, and how such substances may act as natural protectants and /or natural toxicants.
Handbook Of Oxidants And Antioxidants In Exercise
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Author : C. Sen
language : en
Publisher: Elsevier
Release Date : 2000-02-16
Handbook Of Oxidants And Antioxidants In Exercise written by C. Sen and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-16 with Science categories.
Interest in the science of exercise dates back to the time of ancient Greece. Today exercise is viewed not only as a leisurely activity but also as an effective preventive and therapeutic tool in medicine. Further biomedical studies in exercise physiology and biochemistry reports that strenuous physical exercise might cause oxidative lipid damage in various tissues. The generation of reactive oxygen species is elevated to a level that overwhelms the tissue antioxidant defense systems resulting in oxidative stress. The Handbook of Oxidants and Antioxidants in Exercise examines the different aspects of exercise-induced oxidative stress, its management, and how reactive oxygen may affect the functional capacity of various vital organs and tissues. It includes key related issues such as analytical methods, environmental factors, nutrition, aging, organ function and several pathophysiological processes. This timely publication will be of relevance to those in biomedical science and was designed to be readily understood by the general scientific audience.
Glutathione System And Oxidative Stress In Health And Disease
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Author : Margarete Dulce Bagatini
language : en
Publisher:
Release Date : 2020
Glutathione System And Oxidative Stress In Health And Disease written by Margarete Dulce Bagatini and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Glutathione categories.
Basic Principles And Clinical Significance Of Oxidative Stress
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Author : Sivakumar Joghi Thatha Gowder
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-11-11
Basic Principles And Clinical Significance Of Oxidative Stress written by Sivakumar Joghi Thatha Gowder and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-11 with Science categories.
It is a natural phenomenon for all living organisms in the world to undergo different kinds of stress during their life span. Stress has become a common problem for human beings in this materialistic world. In this period, a publication of any material on stress will be helpful for the human society. The book Basic Principles and Clinical Significance of Oxidative Stress targets all aspects of oxidative stress, including principles, mechanisms, and clinical significance. This book covers four sections: Free Radicals and Oxidative Stress, Natural Compounds as Antioxidants, Antioxidants - Health and Disease, and Oxidative Stress and Therapy. Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to scientists, physicians, healthcare professionals, and students who are interested in exploring the effect of stress on human life.
Oxidative Stress
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Author : Helmut Sies
language : en
Publisher:
Release Date : 1991
Oxidative Stress written by Helmut Sies and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.
Life on earth utilizes oxygen and oxygen metabolites in energy conversion, and the constant generation of prooxidants is an essential attribute to aerobic life. This challenge is met by a system of antioxidants in order to maintain a steady state; a disturbance in the prooxidant/antioxidant system is defined as oxidative stress.**In recent years oxidants and antioxidants have attracted widespread interest in many scientific disciplines ranging from free radical chemistry to biochemistry, biology, pharmacology, toxicology, and medicine. This book highlights some of the fascinating research developments in the field, including occurrence of oxidants, defense against oxidants, processes and cell responses, and clinical aspects of oxidative stress. Occurrence of oxidants**Defense against oxidants**Processes and cell response**The role of research in the area of clinical medicine
Cellular Antioxidant Defense Mechanisms
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Author : Ching Kuang Chow
language : en
Publisher: CRC Press
Release Date : 2019-07-17
Cellular Antioxidant Defense Mechanisms written by Ching Kuang Chow and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Medical categories.
First Published in 1988, this three-volume set offers a full insight into the immune systems and its response to antioxidants. Carefully compiled and filled with diagrams, references and information this set is recommended for students of immunology and other professionals in their respective fields.
Leading Edge Antioxidants Research
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Author : Harold V. Panglossi
language : en
Publisher: Nova Publishers
Release Date : 2007
Leading Edge Antioxidants Research written by Harold V. Panglossi and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Antioxidants categories.
In biological systems, the normal processes of oxidation (plus a minor contribution from ionising radiation) produce highly reactive free radicals. These can readily react with and damage other molecules. In some cases the body uses free radicals to destroy foreign or unwanted objects, such as in an infection. However, in the wrong place, the body's own cells may become damaged. Should the damage occur to DNA, the result could be cancer. Antioxidants decrease the damage done to cells by reducing oxidants before they can damage the cell.Virtually all studies of mammals have concluded that a restricted calorie diet extends the lifespan of mammals by as much as 100 percent. This remarkable finding suggests that food is actually more damaging than smoking. As food produces free radicals (oxidants) when metabolised, antioxidant-rich diets are thought to stave off the effects of ageing significantly better than diets lacking in antioxidants. The reduced levels of free radicals, resulting from a reduction in their production by metabolism, is thought to be a major cause of the success of caloric restriction in increasing life span. Antioxidants consist of a group of vitamins including vit
Oxidants In Biology
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Author : Giuseppe Valacchi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-06
Oxidants In Biology written by Giuseppe Valacchi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-06 with Medical categories.
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing. Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
Biomarkers For Antioxidant Defense And Oxidative Damage
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Author : Giancarlo Aldini
language : en
Publisher: John Wiley & Sons
Release Date : 2011-06-09
Biomarkers For Antioxidant Defense And Oxidative Damage written by Giancarlo Aldini and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-09 with Medical categories.
Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications critically evaluates the basic concepts and methodologies of conventional biomarkers as well as current state-of-the-art assays for measuring antioxidant activity/oxidative stress and their practical applications. . Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications will be of a great interest to scientists who are involved in basic research on oxidation, applied scientists evaluating the effects of nutraceuticals or pharmaceutical compounds on antioxidant activity/oxidative stress, and physicians who want to understand the degree of oxidative damage in patients with certain chronic diseases. Discovering sensitive and specific biomarkers for systemic oxidative damage is essential to understand the role of oxidative stress in human disease. Once these roles are clearly understood, we are able to identify novel drug and nutraceutical targets. This volume goes beyond conventional analytical methods of measuring overall antioxidant activity and provides insight to the discovery of biomarkers that reveal information on specific areas of oxidative stress. Contributed by an international list of experts, Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications describes both conventional biomarkers and recent developments in this area. Special Features: Discusses conventional biomarkers as well as recent advances for measuring antioxidants and oxidative stress Biomarkers for lipid peroxidation: isoprostane, hydroxyloctadecaenoic acid, oxysterols, and reactive carbonyl species from lipid peroxidation Biomarkers for protein oxidation: carbonylation, tyrosine oxidation, ubiquitin-conjugation Biomarkers for DNA oxidative damage: comet assay, hydroxylated nucleotides, and exocylcic DNA adducts Recently developed biomarkers from cutting-edge technology