Paclitaxel
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Paclitaxel
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Author : Mallappa Kumara Swamy
language : en
Publisher: Academic Press
Release Date : 2021-10-08
Paclitaxel written by Mallappa Kumara Swamy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-08 with Science categories.
Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer. This is a valuable resource for cancer researchers, biotechnologists and members of biomedical field who are interested in the promising anticancer qualities of this antineoplastic drug and how to enhance them for better treatments. Presents detailed information about Paclitaxel research, from its discovery to clinical uses and biotechnological routes of commercial production Focuses on Paclitaxel development as an effective chemotherapeutic drug, along with its application in different types of cancers Encompasses descriptive illustrations and workflows to help the reader fully understand the content and easily apply it to their research
Paclitaxel
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Author : Diego Morales
language : en
Publisher: Nova Science Publishers
Release Date : 2013
Paclitaxel written by Diego Morales and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Cancer categories.
Paclitaxel is an antimitotic drug that promotes microtubule polymerisation and produces sensitisation to radiation. Paclitaxel is a first-line drug for the treatment of non-small cell lung cancer and is used to treat metastatic ovarian cancer, breast cancer, head and neck cancer, and advanced cases of Kaposi's sarcoma. In this book, the authors discuss the biosynthesis, mechanisms of action and clinical uses of paclitaxel. Topics include paclitaxel resistance and overcoming strategies with structurally or functionally related drugs; molecular mechanisms that mediate resistance to paclitaxel in cancer; the biosynthesis of paclitaxel and its pharmaceutical application for cancer treatment; current status and clinical trials of paclitaxel-containing therapy for urothelial cancer; mesenchymal stromal cells used for carrying and delivering paclitaxel; and the role of paclitaxel in ovarian cancer.
Paclitaxel
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Author : Diego Morales
language : en
Publisher:
Release Date : 2013-01-01
Paclitaxel written by Diego Morales and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-01 with HEALTH & FITNESS categories.
Paclitaxel is an antimitotic drug that promotes microtubule polymerization and produces sensitization to radiation. Paclitaxel is a first-line drug for the treatment of non-small cell lung cancer and is used to treat metastatic ovarian cancer, breast cancer, head and neck cancer, and advanced cases of Kaposi's sarcoma. In this book, the authors discuss the biosynthesis, mechanisms of action and clinical uses of paclitaxel. Topics include paclitaxel resistance and overcoming strategies with structurally or functionally related drugs; molecular mechanisms that mediate resistance to paclitaxel in cancer; the biosynthesis of paclitaxel and its pharmaceutical application for cancer treatment; current status and clinical trials of paclitaxel-containing therapy for urothelial cancer; mesenchymal stromal cells used for carrying and delivering paclitaxel; and the role of paclitaxel in ovarian cancer.
The Story Of Taxol
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Author : Jordan Goodman
language : en
Publisher: Cambridge University Press
Release Date : 2001-03-05
The Story Of Taxol written by Jordan Goodman and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-05 with Juvenile Nonfiction categories.
Taxol is arguably the most celebrated, talked-about and controversial natural product in recent years. It is celebrated because of its efficacy as an anti-cancer drug and because its discovery has provided powerful support for policies concerned with biodiversity; talked about because in the late 1980s and early 1990s the American public was bombarded with news reports and special programmes about the molecule and its host, the Pacific yew; and controversial because during the early 1990s the drug and the tree became embroiled in a number of very sensitive political issues with wide implications for the conduct of public policy. The Story of Taxol tells this story.
Taxol
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Author : Matthew Suffness
language : en
Publisher: CRC Press
Release Date : 2021-12-17
Taxol written by Matthew Suffness and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-17 with Science categories.
This volume brings together all aspects of TAXOL® research, development, and clinical use. It provides comprehensive knowledge of the compound and a perspective of the complex interrelationships needed for its development and production. Each chapter is written by an authority in the field. Chapters are carefully coordinated to maximize information on key topics while avoiding overlap and duplication. Previously unpublished material is presented along with thorough reviews of each topic.
Guidance On The Use Of Paclitaxel In The Treatment Of Ovarian Cancer
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Author : National Institute for Clinical Excellence (Great Britain)
language : en
Publisher:
Release Date : 2003
Guidance On The Use Of Paclitaxel In The Treatment Of Ovarian Cancer written by National Institute for Clinical Excellence (Great Britain) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.
The Current Role Of Paclitaxel In The First Line Chemotherapy Of Ovarian Cancer
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Author :
language : en
Publisher:
Release Date : 1998
The Current Role Of Paclitaxel In The First Line Chemotherapy Of Ovarian Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Medicine categories.
Patlitaxel In Cancer Treatment
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Author : William McGuire
language : en
Publisher: CRC Press
Release Date : 1995-03-14
Patlitaxel In Cancer Treatment written by William McGuire and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-03-14 with Medical categories.
This breakthrough reference-the only book of its kind on the subject-provides in-depth coverage of paclitaxel, one of the most broadly active compounds available to treat human malignancy.
The Chemistry And Pharmacology Of Taxol And Its Derivatives
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Author : H. Timmerman
language : en
Publisher: Elsevier
Release Date : 1995-06-16
The Chemistry And Pharmacology Of Taxol And Its Derivatives written by H. Timmerman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-06-16 with Medical categories.
Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and metastatic breast cancer) may soon be expanded since the drug is showing activity against lung and head-and-neck cancers. The book opens with a review of the naturally occurring taxoids, a chapter which is not a comprehensive list of all taxoids isolated to date, but attempts a systematic approact to describing the different classes of taxoids, with particular reference to all skeletal types and the various functionality patterns. Biosynthetic studies are also discussed, as well as some of the basic chemistry and common functionalities of taxoidic skeleton. Structural identification of taxoids, mostly by spectroscopic means; the formulation of taxanes; the metabolism and pharmacokinetics of Taxol® are also discussed, as are the chemistry of taxanes in relation to SAR studies; SAR aspects of the phenylisoserine side chain; and the mode of action of the taxanes and the mechanisms of resistance. The book is therefore written for medical chemists, in order to stimulate further research in this area and to provide the reader with the necessary background information to start a research program in the area.
Guidance On The Use Of Docetaxel Paclitaxel Gemcitabine And Vinorelbine For The Treatment Of Non Small Cell Lung Cancer
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Author :
language : en
Publisher:
Release Date : 2001
Guidance On The Use Of Docetaxel Paclitaxel Gemcitabine And Vinorelbine For The Treatment Of Non Small Cell Lung Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Lungs categories.