Paleogenomics

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Paleogenomics
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Author : Charlotte Lindqvist
language : en
Publisher: Springer
Release Date : 2019-01-07
Paleogenomics written by Charlotte Lindqvist and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-07 with Science categories.
Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches. Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.
Population Genomics
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Author : Om P. Rajora
language : en
Publisher: Springer
Release Date : 2019-01-07
Population Genomics written by Om P. Rajora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-07 with Science categories.
Population genomics has revolutionized various disciplines of biology including population, evolutionary, ecological and conservation genetics, plant and animal breeding, human health, medicine and pharmacology by allowing to address novel and long-standing questions with unprecedented power and accuracy. It employs large-scale or genome-wide genetic information and bioinformatics to address various fundamental and applied aspects in biology and related disciplines, and provides a comprehensive genome-wide perspective and new insights that were not possible before. These advances have become possible due to the development of new and low-cost sequencing and genotyping technologies and novel statistical approaches and software, bioinformatics tools, and models. Population genomics is tremendously advancing our understanding the roles of evolutionary processes, such as mutation, genetic drift, gene flow, and natural selection, in shaping up genetic variation at individualloci and across the genome and populations; improving the assessment of population genetic parameters or processes such as adaptive evolution, effective population size, gene flow, admixture, inbreeding and outbreeding depression, demography, and biogeography; resolving evolutionary histories and phylogenetic relationships of extant, ancient and extinct species; understanding the genomic basis of fitness, adaptation, speciation, complex ecological and economically important traits, and disease and insect resistance; facilitating forensics, genetic medicine and pharmacology; delineating conservation genetic units; and understanding the genetic effects of resource management practices, and assisting conservation and sustainable management of genetic resources. This Population Genomics book discusses the concepts, approaches, applications and promises of population genomics in addressing most of the above fundamental and applied crucial aspects in a variety of organisms from microorganisms to humans. The book provides insights into a range of emerging population genomics topics including population epigenomics, landscape genomics, seascape genomics, paleogenomics, ecological and evolutionary genomics, biogeography, demography, speciation, admixture, colonization and invasion, genomic selection, and plant and animal domestication. This book fills a vacuum in the field and is expected to become a primary reference in Population Genomics world-wide.
Frontiers In Developmental Biology
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Author : Robert A. Meyers
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-02
Frontiers In Developmental Biology written by Robert A. Meyers and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-02 with Science categories.
Dieser aktuelle Band aus der renommierten enzyklopädischen Reihe ist der erste in vielen Jahren, der alle wichtigen Aspekte der Entwicklungsbiologie vereint, von der Morphogenese und Organogenese, über die epigenetische Regulation der Genexpression bis hin zur evolutionären Entwicklungsbiologie. Der Herausgeber hat ein herausragendes Team zusammengestellt, das diese Themen beleuchtet, und damit ein wegweisendes Werk für die kommenden Jahre geschaffen. Das Ergebnis ist ein einzigartiges, herausragendes Referenzwerk der Entwicklungsbiologie für Forscher, Studenten und Fachexperten.
Africa The Cradle Of Human Diversity
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Author :
language : en
Publisher: BRILL
Release Date : 2021-11-22
Africa The Cradle Of Human Diversity written by and has been published by BRILL this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-22 with History categories.
This book explores important chapters of past and recent African history from a multidisciplinary perspective. It covers an extensive time range from the evolution of early humans to the complex cultural and genetic diversity of modern-day populations in Africa. Through a comprehensive list of chapters, the book focuses on different time-periods, geographic regions and cultural and biological aspects of human diversity across the continent. Each chapter summarises current knowledge with perspectives from a varied set of international researchers from diverse areas of expertise. The book provides a valuable resource for scholars interested in evolutionary history and human diversity in Africa. Contributors are Shaun Aron, Ananyo Choudhury, Bernard Clist, Cesar Fortes-Lima, Rosa Fregel, Jackson S. Kimambo, Faye Lander , Marlize Lombard, Fidelis T. Masao, Ezekia Mtetwa, Gilbert Pwiti, Michèle Ramsay, Thembi Russell, Carina Schlebusch, Dhriti Sengupta, Plan Shenjere-Nyabezi, Mário Vicente.
Working With And For Ancestors
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Author : Chelsea H. Meloche
language : en
Publisher: Routledge
Release Date : 2020-11-29
Working With And For Ancestors written by Chelsea H. Meloche and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-29 with Social Science categories.
Working with and for Ancestors examines collaborative partnerships that have developed around the study and care of Indigenous ancestral human remains. In the interest of reconciliation, museums and research institutions around the world have begun to actively seek input and direction from Indigenous descendants in establishing collections care and research policies. However, true collaboration is difficult, time-consuming, and sometimes awkward. By presenting examples of projects involving ancestral remains that are successfully engaged in collaboration, the book provides encouragement for scientists and descendant communities alike to have open and respectful discussions around the research and care of ancestral human remains. Key themes for discussion include new approaches to the care for ancestors; the development of culturally sensitive museum policies; the emergence of mutually beneficial research partnerships; and emerging issues such as those of intellectual property, digital data, and alternatives to destructive analyses. Critical discussions by leading scholars also identify the remaining challenges in the repatriation process and offer a means to continue moving forward. This volume will appeal to a broad, interdisciplinary audience interested in collaborative research and management strategies that are aimed at developing mutually beneficial relationships between researchers and descendant communities. This includes students and researchers in archaeology, anthropology, museums studies, and Indigenous communities.
Genomics Based Approaches For Tropical Tree Improvement And Conservation
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Author : Ani A. Elias
language : en
Publisher: Springer Nature
Release Date : 2025-04-30
Genomics Based Approaches For Tropical Tree Improvement And Conservation written by Ani A. Elias and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-30 with Technology & Engineering categories.
This book offers foundational knowledge to advance genomic approaches in forest tree improvement and genetic resource conservation. The tropical tree breeding sector has fallen behind in genomic breeding not due to a lack of resources but rather a limited understanding and an underdeveloped genomic breeding pipeline. While marker-assisted selection (MAS) has been the preferred method for incorporating genomic data into breeding programs, it primarily targets major genes, overlooking minor gene effects. This limitation makes MAS less effective for enhancing quantitative traits such as heartwood content. The primary goal of statistical methodologies using whole-genome information is to predict promising candidates for breeding advancement/commercialization while efficiently managing resources such as land, labor, and, most critically, time. Given the long rotation period of forest tree crops, the ability to identify, select, and modify genotypes with high heritability for economically valuable traits within a shorter timeframe marks a significant advancement in breeding. This book provides comprehensive guidelines on leveraging genomic data, including pathogenomics, to breed resilient, future-ready trees and manage populations effectively. To reinforce these guidelines, the book presents case studies on species such as Tectona grandis, Santalum album, Casuarina, Shorea, Artocarpus, tropical and sub-tropical pines, and tropical fruit trees. Additionally, the book explores broader applications of genetic data, including timber tracing and the conservation of germplasm while minimizing genetic redundancy. This book will be a valuable resource for tropical tree breeders and researchers, equipping them with the methods and tools needed to adopt advanced genomic breeding. Additionally, students and scholars will benefit from the comprehensive information it provides, enhancing their understanding of modern breeding techniques.
Genomics Of Plant Genetic Resources
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Author : Roberto Tuberosa
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-08
Genomics Of Plant Genetic Resources written by Roberto Tuberosa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-08 with Science categories.
Our lives and well being intimately depend on the exploitation of the plant genetic resources available to our breeding programs. Therefore, more extensive exploration and effective exploitation of plant genetic resources are essential prerequisites for the release of improved cultivars. Accordingly, the remarkable progress in genomics approaches and more recently in sequencing and bioinformatics offers unprecedented opportunities for mining germplasm collections, mapping and cloning loci of interest, identifying novel alleles and deploying them for breeding purposes. This book collects 48 highly interdisciplinary articles describing how genomics improves our capacity to characterize and harness natural and artificially induced variation in order to boost crop productivity and provide consumers with high-quality food. This book will be an invaluable reference for all those interested in managing, mining and harnessing the genetic richness of plant genetic resources.
The Ethics And Challenges Of Studying The Genetics Of Marginalized Populations
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Author : Arslan A. Zaidi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-25
The Ethics And Challenges Of Studying The Genetics Of Marginalized Populations written by Arslan A. Zaidi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-25 with Science categories.
A Companion To Biological Anthropology
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Author : Clark Spencer Larsen
language : en
Publisher: John Wiley & Sons
Release Date : 2023-03-10
A Companion To Biological Anthropology written by Clark Spencer Larsen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-10 with Social Science categories.
A Companion to Biological Anthropology The discipline of biological anthropology—the study of the variation and evolution of human beings and their evolutionary relationships with past and living hominin and primate relatives—has undergone enormous growth in recent years. Advances in DNA research, behavioral anthropology, nutrition science, and other fields are transforming our understanding of what makes us human. A Companion to Biological Anthropology provides a timely and comprehensive account of the foundational concepts, historical development, current trends, and future directions of the discipline. Authoritative yet accessible, this field-defining reference work brings together 37 chapters by established and younger scholars on the biological and evolutionary components of the study of human development. The authors discuss all facets of contemporary biological anthropology including systematics and taxonomy, population and molecular genetics, human biology and functional adaptation, early primate evolution, paleoanthropology, paleopathology, bioarchaeology, forensic anthropology, and paleogenetics. Updated and expanded throughout, this second edition explores new topics, revisits key issues, and examines recent innovations and discoveries in biological anthropology such as race and human variation, epidemiology and catastrophic disease outbreaks, global inequalities, migration and health, resource access and population growth, recent primate behavior research, the fossil record of primates and humans, and much more. A Companion to Biological Anthropology, Second Edition is an indispensable guide for researchers and advanced students in biological anthropology, geosciences, ancient and modern disease, bone biology, biogeochemistry, behavioral ecology, forensic anthropology, systematics and taxonomy, nutritional anthropology, and related disciplines.
Next Generation Genome Sequencing
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Author : Michal Janitz
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-24
Next Generation Genome Sequencing written by Michal Janitz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-24 with Science categories.
Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug discovery and health care. As such, it presents a detailed comparative analysis of commercially available platforms as well as insights into alternative, emerging sequencing techniques. In addition, the book not only covers the principles of DNA sequencing techniques but also social, ethical and commercial aspects, the concept of personalized medicine and a five-year perspective of DNA sequencing.