Parasite Infections From Experimental Models To Natural Systems
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Parasite Infections From Experimental Models To Natural Systems
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Author : Toni Aebischer
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-06
Parasite Infections From Experimental Models To Natural Systems written by Toni Aebischer and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-06 with categories.
Eukaryotic parasites (including parasitic protozoans, worms and arthropods) are more complex and heterogeneous organisms than pathogenic bacteria and viruses. This notion implies different evolutionary strategies of host exploitation. Typically, parasites establish long-term infections and induce relatively little mortality, as they often limit pathological changes by modulating host cells and downregulating adverse immune responses. Their pattern of distribution tends to be endemic rather than epidemic. Despite these seemingly benign traits, parasites usually cause substantial chronic morbidity, thus constituting an enormous socioeconomic burden in humans, particularly in resource poor countries, and in livestock worldwide. Parasite-induced fitness costs are an evolutionary force that can shape populations and contribute to species diversity. Therefore, a thorough understanding of parasites and parasitic diseases requires detailed knowledge of the respective biochemical, molecular and immunological aspects as well as of population genetics, epidemiology and ecology. This Research Topic (RT) bridges disciplines to connect molecular, immunological and wildlife aspects of parasitic infections. The RT puts emphases on four groups of parasites: Plasmodium, Toxoplasma, Giardia and intestinal helminths. Co-infections are also covered by the RT as they represent the most common form of parasite infections in wildlife and domestic animal populations. Within the four types of parasites the following topics are addressed: (1) Experimental models: hypothesis testing, translation and limits. (2) Critical appraisal of experimental models. (3) Natural systems: Technological advances for investigations in natural parasite-host systems and studies in natural systems. (4) The urgent need for better models and methods in natural parasite systems. Hence, the RT covers and illustrate by the means of four main parasitic infections the parasite-host system at the molecular, cellular and organismic level.
Parasite Infections From Experimental Models To Natural Systems
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Author :
language : en
Publisher:
Release Date : 2018
Parasite Infections From Experimental Models To Natural Systems written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
Eukaryotic parasites (including parasitic protozoans, worms and arthropods) are more complex and heterogeneous organisms than pathogenic bacteria and viruses. This notion implies different evolutionary strategies of host exploitation. Typically, parasites establish long-term infections and induce relatively little mortality, as they often limit pathological changes by modulating host cells and downregulating adverse immune responses. Their pattern of distribution tends to be endemic rather than epidemic. Despite these seemingly benign traits, parasites usually cause substantial chronic morbidity, thus constituting an enormous socioeconomic burden in humans, particularly in resource poor countries, and in livestock worldwide. Parasite-induced fitness costs are an evolutionary force that can shape populations and contribute to species diversity. Therefore, a thorough understanding of parasites and parasitic diseases requires detailed knowledge of the respective biochemical, molecular and immunological aspects as well as of population genetics, epidemiology and ecology. This Research Topic (RT) bridges disciplines to connect molecular, immunological and wildlife aspects of parasitic infections. The RT puts emphases on four groups of parasites: Plasmodium, Toxoplasma, Giardia and intestinal helminths. Co-infections are also covered by the RT as they represent the most common form of parasite infections in wildlife and domestic animal populations. Within the four types of parasites the following topics are addressed: (1) Experimental models: hypothesis testing, translation and limits. (2) Critical appraisal of experimental models. (3) Natural systems: Technological advances for investigations in natural parasite-host systems and studies in natural systems. (4) The urgent need for better models and methods in natural parasite systems. Hence, the RT covers and illustrate by the means of four main parasitic infections the parasite-host system at the molecular, cellular and organismic level.
Wildlife Disease Ecology
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Author : Kenneth Wilson
language : en
Publisher: Cambridge University Press
Release Date : 2019-11-14
Wildlife Disease Ecology written by Kenneth Wilson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-14 with Mathematics categories.
Introduces readers to key case studies that illustrate how theory and data can be integrated to understand wildlife disease ecology.
Controlling Intestinal Helminths While Eliminating Lymphatic Filariasis
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Author : L. S. Stephenson
language : en
Publisher: Cambridge University Press
Release Date : 2001-11-16
Controlling Intestinal Helminths While Eliminating Lymphatic Filariasis written by L. S. Stephenson and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-16 with Medical categories.
Reviews the WHO Global Programme to Eliminate Lymphatic Filariasis and its potential impact for health.
Immunity To Parasitic Infection
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Author : Tracey Lamb
language : en
Publisher: John Wiley & Sons
Release Date : 2012-08-10
Immunity To Parasitic Infection written by Tracey Lamb and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-10 with Science categories.
Parasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system. This book examines current knowledge about immune responses to parasitic infections affecting humans, including interactions that occur during co-infections, and how immune responses may be manipulated to develop therapeutic interventions against parasitic infection. For easy reference, the most commonly studied parasites are examined in individual chapters written by investigators at the forefront of their field. An overview of the immune system, as well as introductions to protozoan and helminth parasites, is included to guide background reading. A historical perspective of the field of immunoparasitology acknowledges the contributions of investigators who have been instrumental in developing this field of research.
Parasitic Infections And The Immune System
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Author : Felipe Kierzenbaum
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Parasitic Infections And The Immune System written by Felipe Kierzenbaum and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Featuring the work of several world authorities, this volume places primary emphasis on the mechanism of parasite produced changes in the immune response (i.e. immunosuppression). The text covers parasitic diseases on which the World Health Organization has aggressively promoted research through its Program on Research and Training In Tropical Diseases. Chapters cover parasitic diseases such as malaria, American trypanosomiasis (Chagas' disease), African trypanosomiasis (sleeping sickness), leishmaniasis, schistosomiasis and onchocerciasis. Also included are discussions of toxoplasmosis and amebiasis. The material is drawn from the body of literature that has been rapidly accumulating for the last 15 years. An important feature of this text is that the contributors first outline existing knowledge about the immunology of each infection, thereby enabling the reader to more easily appreciate why and how the immunological alterations that accompany a disease are important, and then, to review the postulated mechanisms for such alterations. Consequently, the impact that each parasitic infection has on the immune system is always described in the "heart" of each chapter rather than at the beginning.
Parasitic Nematodes
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Author : Malcolm W. Kennedy
language : en
Publisher: CABI
Release Date : 2013
Parasitic Nematodes written by Malcolm W. Kennedy and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Medical categories.
Covering a wide range of rapidly-developing fields of research into parasitic nematodes, this comprehensive volume discusses the genetics, biochemistry and immunology of nematode parasites of humans as well as domestic animals and plants. This fully-updated edition also covers new advances including horizontal gene transfer, immune expulsion mechanisms, genetics of susceptibility in humans, nematode protein structures, role of bacterial symbionts, intrinsic immune response, host immune system modulation, modulation of allergic and autoimmune diseases and the use of parasitic nematodes or their products as therapeutics.
Handbook Of Laboratory Animal Science
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Author : Jann Hau
language : en
Publisher: CRC Press
Release Date : 2004-11-29
Handbook Of Laboratory Animal Science written by Jann Hau and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-11-29 with Medical categories.
Building upon the success of the Handbook of Laboratory Animal Science and completing Volumes I and II of the Second Edition, Handbook of Laboratory Animal Science, Second Edition: Animal Models, Volume III provides the final component to present a comprehensive overview of animal models in biomedical research.As with Volume II, this new volume add
Handbook Of Laboratory Animal Science Volume Iii
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Author : Jann Hau
language : en
Publisher: CRC Press
Release Date : 2013-12-26
Handbook Of Laboratory Animal Science Volume Iii written by Jann Hau and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-26 with Medical categories.
While replacing and reducing the use of laboratory animals are integral parts of the 3Rs-replace, reduce, refine-which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestsel
Handbook Of Laboratory Animal Science Volume Iii Third Edition
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Author : Jann Hau
language : en
Publisher: CRC Press
Release Date : 2013-12-26
Handbook Of Laboratory Animal Science Volume Iii Third Edition written by Jann Hau and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-26 with Medical categories.
While replacing and reducing the use of laboratory animals are integral parts of the 3Rs—replace, reduce, refine—which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestselling previous edition, the Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models complements volumes I and II of the third edition by completing the task of providing a comprehensive overview of animal models in all biomedical disciplines. The three Rs have been integrated throughout this handbook to promote efficient and humane experimental work with animals. Written by international experts, each chapter focuses on an important subdiscipline of laboratory animal science and can be used as a stand-alone text. This volume contains new chapters for six additional disease animal models: spinal cord injury, cardiovascular diseases, sudden infant death syndrome, developmental disorders, eye diseases, and human cancer. It also presents a new chapter on applying reduction and refinement to animal models. This handbook can be used for undergraduate and postgraduate laboratory animal science courses, and as a handbook for scientists who work with animals in their research, for university veterinarians, for regulators, and for other specialists in laboratory animal science.