Particles And Health 2021 An International Conference Addressing Issues In Science And Regulation
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Particles And Health 2021 An International Conference Addressing Issues In Science And Regulation
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Author : Robert McCunney
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-30
Particles And Health 2021 An International Conference Addressing Issues In Science And Regulation written by Robert McCunney and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-30 with Medical categories.
Particles and Health is an international conference taking place in October 2021 addressing issues in science and regulation. Regulatory initiatives in the European Union (EU) have suggested uniform hazard classifications for all poorly soluble low toxicity particles (PSLTs). Examples of PSLTs include carbon black, titanium dioxide and iron oxide, among others. Approaches have also been proposed for setting workplace exposure limits for PSLTs such as those of the German MAK Commission. The conference will include specific sections over a two day period of about 25 presentations, associated with PSLTs regarding the following major topics: (1) human studies, (2) animal inhalation studies associated with lung cancer,(3) animal and human studies associated with non pulmonary impacts, including reproductive, genetic and cardiac effects, and (4) regulatory application of scientific studies. This conference will include presentations regarding: Definition of PSLT’s with attention to both similarities and differences among these substances. • Address scientific studies regarding human health effects of PSLTs. The value of human studies over animal studies-when human-exposed populations can be studied adequately- will be emphasized. • Address translational toxicology challenges, including the appropriateness of rats as models for human lung pathogenesis (particularly lung cancer) in light of lung overload phenomena and species differences. • Serve as a platform to present current scientific information about PSLTs important for regulatory action. • Publication of pertinent conference presentations in the peer reviewed scientific literature will allow the presentations to live beyond the conference and subsequently be reviewed part of regulatory deliberations. • Establish an interdisciplinary setting for industry, academia and regulatory professionals to interact on an important topic. Such interaction can facilitate enhanced understanding of the science and ideally, more appropriate regulations, appropriate classification and labeling as well as for setting exposure limits, among others. • Recommend areas for further clarifying research regarding the significance of the rat as a model for translation toxicology. The goal of this conference is to present current scientific evidence regarding the numerous dimensions of particles and health and to facilitate interaction and discussions among attendees with expertise in toxicology, epidemiology, occupational and pulmonary medicine and exposure assessment. Interactions between these disciplines will aid in the sound and evidence-based scientific underpinning of regulatory considerations regarding PSLTs. Although regulatory concern regarding PSLTs has focused on lung cancer risk as a result of rat inhalation overload studies, this conference will address all relevant health end points, including genetic and reproductive issues as well, consistent with ECHA guidelines. Sample of Topics related to substances that may be characterized as PSLTs, including carbon black, coal, titanium dioxide, cerium oxide, aluminum oxide barium sulfate and iron oxide, among others. • Defining PSLTs • Epidemiological studies of PSLTs • Inhalation studies evaluating human cellular response to particles • Basic research studies on inflammatory to malignancy pathways • Animal studies, PLSTs and human risk: “New Insights into old data.” • New studies on PSLTs; 2 year carcinogenicity assays • Animal studies and gender specific responses to PSLTs. How does the USA National Cancer Institute (NCI) and National Institute of Environmental Health Sciences (NIEHS) address this challenge of extrapolating rodent data to human risk assessment? • Role of the rodent model in human risk assessment of PSLTs and lung cancer risk • Adverse Outcome Pathways (AOPs) and Modes of Action (MOA): identification and recommendations for closing gaps in knowledge for rodents and humans. • Are there lessons to be learned from how the pharmaceutical industry’s approach to translational science (safety and efficacy) as evolved in recent years? • Setting exposure limits for PSLTs and Translational Toxicology. • Genotoxicity and Reproductive toxicity studies of PSLTs.
Sricoenv 2022
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Author : Hermione Froehlicher
language : en
Publisher: European Alliance for Innovation
Release Date : 2023-04-12
Sricoenv 2022 written by Hermione Froehlicher and has been published by European Alliance for Innovation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-12 with Nature categories.
The 3rd Sriwijaya International Conference on Environmental Issues (3rd SRICOENV) 2022 was successfully held on OCTOBER 5th, 2022, in Palembang, South Sumatera-Indonesia (virtual conference). The 3rd SRICOENV 2022 created a forum for exchanging ideas and research results, opened new perspectives in related fields and broadened the horizons of all participants. The conference was attended by 350 people from all over the world. The conference was divided into three parts, including keynote lectures, oral presentations and online discussions. First, the keynote speakers had 30-45 minutes to present. Then, in the oral presentations, their authors presented the outstanding papers we selected individually. We are pleased to announce that we have selected many high-quality papers from the submissions and included them in the conference proceedings after a rigorous review. These papers cover all environmental topics to present the state of the art in environmental and climate change issues. All papers have undergone rigorous review to meet the requirements for publication. We would like to thank everyone who supported the 3rd SRICOENV 2022 and made it a great success. In particular, we would like to thank the European Alliance for Innovation (EAI) for the hard work of all their colleagues in publishing this volume. We sincerely hope that the 3rd SRICOENV 2022 was a forum for excellent discussions, enabling new ideas and promoting collaborative research.
Oecd Science Technology And Innovation Outlook 2021 Times Of Crisis And Opportunity
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2021-01-12
Oecd Science Technology And Innovation Outlook 2021 Times Of Crisis And Opportunity written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-12 with categories.
In immediate responses to the COVID-19 crisis, science and innovation are playing essential roles in providing a better scientific understanding of the virus, as well as in the development of vaccines, treatments and diagnostics. Both the public and private sectors have poured billions of dollars into these efforts, accompanied by unprecedented levels of global cooperation.
Particle Toxicology
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Author : Ken Donaldson
language : en
Publisher: CRC Press
Release Date : 2006-12-21
Particle Toxicology written by Ken Donaldson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-21 with Medical categories.
Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to transl
Translational Toxicology
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Author : Claude L. Hughes
language : en
Publisher: Humana Press
Release Date : 2016-03-23
Translational Toxicology written by Claude L. Hughes and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-23 with Medical categories.
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.
Climate Change And Cities
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Author : Cynthia Rosenzweig
language : en
Publisher:
Release Date : 2018-03-29
Climate Change And Cities written by Cynthia Rosenzweig and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-29 with Nature categories.
Climate Change and Cities bridges science-to-action for climate change adaptation and mitigation efforts in cities around the world.
Plastics And Microplastics
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Author : David E. Newton
language : en
Publisher: Bloomsbury Publishing USA
Release Date : 2021-07-19
Plastics And Microplastics written by David E. Newton and has been published by Bloomsbury Publishing USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-19 with Political Science categories.
Plastic plays a vital role in today's world but has become increasingly problematic. Plastics and Microplastics: A Reference Handbook discusses the history and evolution of plastic and its many uses, both in the United States and around the world. Beginning with a history of plastic—from the first scientific discovery of the material to its diversity of forms and uses in the present day—Plastics and Microplastics: A Reference Handbook discusses the history and evolution of plastic and its many uses, both in the United States and around the world. Importantly, it delves into the problems and controversies concerning plastic and microplastics, such as the pollution of oceans, rivers, and streams; its exceptionally long shelf life; its contribution to air pollution; and ingestion of microplastics by marine life. One of the most valuable aspects of the book is its survey of the history of plastics and microplastics conducted in a manner that helps readers to identify key issues to address. Moreover, it discusses both implemented and proposed solutions. A perspectives chapter includes a broad range of voices, allowing crucial, diverse perspectives to round out the author's expertise.
How To Talk To A Science Denier
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Author : Lee McIntyre
language : en
Publisher: MIT Press
Release Date : 2022-08-02
How To Talk To A Science Denier written by Lee McIntyre and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-02 with Science categories.
Can we change the minds of science deniers? Encounters with flat earthers, anti-vaxxers, coronavirus truthers, and others. "Climate change is a hoax--and so is coronavirus." "Vaccines are bad for you." These days, many of our fellow citizens reject scientific expertise and prefer ideology to facts. They are not merely uninformed--they are misinformed. They cite cherry-picked evidence, rely on fake experts, and believe conspiracy theories. How can we convince such people otherwise? How can we get them to change their minds and accept the facts when they don't believe in facts? In this book, Lee McIntyre shows that anyone can fight back against science deniers, and argues that it's important to do so. Science denial can kill. Drawing on his own experience--including a visit to a Flat Earth convention--as well as academic research, McIntyre outlines the common themes of science denialism, present in misinformation campaigns ranging from tobacco companies' denial in the 1950s that smoking causes lung cancer to today's anti-vaxxers. He describes attempts to use his persuasive powers as a philosopher to convert Flat Earthers; surprising discussions with coal miners; and conversations with a scientist friend about genetically modified organisms in food. McIntyre offers tools and techniques for communicating the truth and values of science, emphasizing that the most important way to reach science deniers is to talk to them calmly and respectfully--to put ourselves out there, and meet them face to face.
Recent Hurricane Research
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Author : Anthony Lupo
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-04-19
Recent Hurricane Research written by Anthony Lupo and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-19 with Science categories.
This book represents recent research on tropical cyclones and their impact, and a wide range of topics are covered. An updated global climatology is presented, including the global occurrence of tropical cyclones and the terrestrial factors that may contribute to the variability and long-term trends in their occurrence. Research also examines long term trends in tropical cyclone occurrences and intensity as related to solar activity, while other research discusses the impact climate change may have on these storms. The dynamics and structure of tropical cyclones are studied, with traditional diagnostics employed to examine these as well as more modern approaches in examining their thermodynamics. The book aptly demonstrates how new research into short-range forecasting of tropical cyclone tracks and intensities using satellite information has led to significant improvements. In looking at societal and ecological risks, and damage assessment, authors investigate the use of technology for anticipating, and later evaluating, the amount of damage that is done to human society, watersheds, and forests by land-falling storms. The economic and ecological vulnerability of coastal regions are also studied and are supported by case studies which examine the potential hazards related to the evacuation of populated areas, including medical facilities. These studies provide decision makers with a potential basis for developing improved evacuation techniques.
Social Science Research
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Author : Anol Bhattacherjee
language : en
Publisher: CreateSpace
Release Date : 2012-04-01
Social Science Research written by Anol Bhattacherjee and has been published by CreateSpace this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-01 with Science categories.
This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.