Pathogenesis Diagnostics Treatments Of Mycobacterium Tuberculosis And Its Co Infection With Hiv Or Sars Cov 2
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Pathogenesis Diagnostics Treatments Of Mycobacterium Tuberculosis And Its Co Infection With Hiv Or Sars Cov 2
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Author : Amit Singh
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-30
Pathogenesis Diagnostics Treatments Of Mycobacterium Tuberculosis And Its Co Infection With Hiv Or Sars Cov 2 written by Amit Singh and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-30 with Medical categories.
Mycobacterium tuberculosis is the major cause of tuberculosis (TB) across the globe. Around one-fourth of the world’s population is infected with TB asymptomatically. Longer regimen of anti-TB drugs (longer treatment leading to poor adherence to treatment), interrupted anti-TB drugs treatment (long regimen with incomplete anti-TB treatment), and ineffectiveness of the anti-TB drugs due to the re-emergence of latent TB infections are just a few mechanisms that play a major hindrance to achieving the end of the global TB epidemic by 2035 as WHO plans. The emergence of drug-resistant in Mycobacterium tuberculosis and co-infections with HIV as well as SARS-CoV-2 poses a serious threat to global health agencies. It was reported that the TB cases in India and other endemic countries are two to three times higher than in the last few years. Different mechanisms were acquired by the bacteria to become multidrug-resistant such as an alternation in the target site, drug efflux by overexpression of efflux pumps, inactivation of drugs by enzymes and biofilms. Mechanisms adopted by bacteria and longer anti-tuberculosis treatment regimens are the greatest threat in TB control programs especially in malnourished, immune-compromised, M. tuberculosis co-infection with HIV and SARS-CoV-2 individuals in developing countries. There is a great need for shorter anti-TB regimens and novel drugs with a different mode of action to encounter the emergence of drug resistance in Mycobacterium tuberculosis. Combinatorial drug treatments by anti-TB drugs along with the repurposed drugs are also the novel choice against this deadly TB. The current issue will focus on different mechanisms adopted by mycobacterium to develop multidrug-resistant mycobacteria and the impact of SARS-CoV-2 pandemics in TB treatment and management. Furthermore, the modern techniques used for the early diagnosis and management of M. tuberculosis and its co-infection with HIV and SARS-CoV-2 are the point of innovative interest that shows the potential development in technologies and applications for the management of these co-infections.
Disease Control Priorities Third Edition Volume 6
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Author : King K. Holmes
language : en
Publisher: World Bank Publications
Release Date : 2017-11-06
Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-06 with Medical categories.
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Case Studies In Infectious Disease Mycobacterium Tuberculosis
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Author : Peter Lydyard
language : en
Publisher: Garland Science
Release Date : 2009-12
Case Studies In Infectious Disease Mycobacterium Tuberculosis written by Peter Lydyard and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12 with Medical categories.
Case Studies in Infectious Disease: Mycobacterium tuberculosis presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.
Understanding The Host Immune Response Against Mycobacterium Tuberculosis Infection
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Author : Vishwanath Venketaraman
language : en
Publisher: Springer
Release Date : 2018-09-26
Understanding The Host Immune Response Against Mycobacterium Tuberculosis Infection written by Vishwanath Venketaraman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-26 with Medical categories.
According to the World Health Organization, approximately one third of the world’s population is latently infected with Mycobacterium tuberculosis (M. tb [LTBI]), of whom about 9 million have active tuberculosis (TB). It is estimated that approximately 2 million individuals die each year from active TB. An estimated 14.4% of these individuals have HIV and M. tb co-infection. TB has long been known to be one of the leading causes of death in HIV-infected individuals. Recent evidence now indicates that individuals with type 2 diabetes, the elderly, and chronic smokers are also increasingly susceptible to TB infection, the ability of their immune system to fight off active TB infection having been compromised by their condition. This book therefore aims to provide a detailed review of recent advances in the research that involves characterizing the host’s immune responses against TB infection in conditions such as HIV, diabetes, chronic cigarette smoking and aging, and strategies to restore favorable immune responses against this deadly pathogen.
Tuberculosis And Co Infection With Hiv Aids
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Author : Pranveer Singh
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2019-10-09
Tuberculosis And Co Infection With Hiv Aids written by Pranveer Singh and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-09 with Medical categories.
This book deals with Tuberculosis in exhaustive detail. It incorporates the most recent research on the disease, and is divided into different sections highlighting the chronological history of its development, global spread, the current scenario in India with regards to the disease, seasonality, co-infection with HIV-AIDS, and the novel combinatorial-therapy with special reference to underprivileged and tribal populations. Avoiding lengthy and irrelevant descriptions, it will help the reader, particularly students, to grasp the facts. The book is supplemented with figures and ray diagrams to allow full visualisation of the concepts discussed.
Re Emergence Of Neglected Tropical Diseases Amid The Covid 19 Pandemic Epidemiology Transmission Mitigation Strategies And Recent Advances In Chemotherapy And Vaccines
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Author : Ranjan K. Mohapatra
language : en
Publisher: Frontiers Media SA
Release Date : 2023-11-09
Re Emergence Of Neglected Tropical Diseases Amid The Covid 19 Pandemic Epidemiology Transmission Mitigation Strategies And Recent Advances In Chemotherapy And Vaccines written by Ranjan K. Mohapatra and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-09 with Science categories.
Global Infectious Disease Surveillance And Detection
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2007-11-11
Global Infectious Disease Surveillance And Detection written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-11 with Medical categories.
Early detection is essential to the control of emerging, reemerging, and novel infectious diseases, whether naturally occurring or intentionally introduced. Containing the spread of such diseases in a profoundly interconnected world requires active vigilance for signs of an outbreak, rapid recognition of its presence, and diagnosis of its microbial cause, in addition to strategies and resources for an appropriate and efficient response. Although these actions are often viewed in terms of human public health, they also challenge the plant and animal health communities. Surveillance, defined as "the continual scrutiny of all aspects of occurrence and spread of a disease that are pertinent to effective control", involves the "systematic collection, analysis, interpretation, and dissemination of health data." Disease detection and diagnosis is the act of discovering a novel, emerging, or reemerging disease or disease event and identifying its cause. Diagnosis is "the cornerstone of effective disease control and prevention efforts, including surveillance." Disease surveillance and detection relies heavily on the astute individual: the clinician, veterinarian, plant pathologist, farmer, livestock manager, or agricultural extension agent who notices something unusual, atypical, or suspicious and brings this discovery in a timely way to the attention of an appropriate representative of human public health, veterinary medicine, or agriculture. Most developed countries have the ability to detect and diagnose human, animal, and plant diseases. Global Infectious Disease Surveillance and Detection: Assessing the Challenges-Finding Solutions, Workshop Summary is part of a 10 book series and summarizes the recommendations and presentations of the workshop.
Sars Mers And Other Viral Lung Infections
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Author : David S. Hui
language : en
Publisher: European Respiratory Society
Release Date : 2016-06-01
Sars Mers And Other Viral Lung Infections written by David S. Hui and has been published by European Respiratory Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-01 with Medical categories.
Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.
Who Consolidated Guidelines On Tuberculosis
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Author : World Health Organization
language : en
Publisher:
Release Date : 2022
Who Consolidated Guidelines On Tuberculosis written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
The WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment - Tuberculosis Care and Support informs health care professionals in Member States on how to improve treatment and care for patients with TB. These guidelines group all recommendations on TB care and support in one document and are complemented by an operational handbook. The guidelines are to be used primarily by national TB programmes, or their equivalents in Ministries of Health, stakeholders and technical organizations working on TB care in the public and private sectors and in the community.
Mycobacterium Tuberculosis Pathogenesis Infection Prevention And Treatment
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Author : Riccardo Miggiano
language : en
Publisher: Mdpi AG
Release Date : 2020-10
Mycobacterium Tuberculosis Pathogenesis Infection Prevention And Treatment written by Riccardo Miggiano and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10 with Science categories.
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled "Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment" that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.