Patient Derived Xenografts
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Patient Derived Tumor Xenograft Models
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Author : Rajesh Uthamanthil
language : en
Publisher: Academic Press
Release Date : 2016-10-13
Patient Derived Tumor Xenograft Models written by Rajesh Uthamanthil and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-13 with Medical categories.
Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry
Patient Derived Xenografts
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Author : Mohamed I. Saad
language : en
Publisher: Springer Nature
Release Date :
Patient Derived Xenografts written by Mohamed I. Saad and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Patient Derived Xenograft Models Of Human Cancer
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Author : Yuzhuo Wang
language : en
Publisher: Springer
Release Date : 2017-06-27
Patient Derived Xenograft Models Of Human Cancer written by Yuzhuo Wang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-27 with Medical categories.
This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field.
Patient Derived Mouse Models Of Cancer
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Author : Robert M. Hoffman
language : en
Publisher: Humana
Release Date : 2018-06-15
Patient Derived Mouse Models Of Cancer written by Robert M. Hoffman and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-15 with Medical categories.
This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently available and the transplantation techniques that can be used as well as state-of-the-art imaging techniques. Practical applications of the models from drug discovery, genome analysis to personalized treatment are also covered. Written by experts in that field, each of these sections address these critical issues. A brief review of the existing literature addressing the particular topic follows in each section. Presently, there is no single source to provide information on technique and uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists, pharmaceutical and biotechnology industry scientists as well as molecular biologists studying in vivo systems
Patient Derived Mouse Models Of Cancer
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Author : Robert M. Hoffman
language : en
Publisher: Springer
Release Date : 2017-08-01
Patient Derived Mouse Models Of Cancer written by Robert M. Hoffman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-01 with Medical categories.
This text highlights seminal discoveries and also provides comprehensive and state-of the-art approach to mouse models of human patient tumors. These areas include training, basic techniques, as well as general troubleshooting. Subsequent chapters focus on the different mouse models of patient tumors including the various strains of immunodeficient mice currently available and the transplantation techniques that can be used as well as state-of-the-art imaging techniques. Practical applications of the models from drug discovery, genome analysis to personalized treatment are also covered. Written by experts in that field, each of these sections address these critical issues. A brief review of the existing literature addressing the particular topic follows in each section. Presently, there is no single source to provide information on technique and uses of mouse models of human patient tumors. Patient-Derived Mouse Models of Cancer will satisfy this need for cancer researchers, oncologists, pharmaceutical and biotechnology industry scientists as well as molecular biologists studying in vivo systems
Patient Derived Xenografts As Pre Clinical Models Of Response To Chemotherapy
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Author : Paulina Cybulska
language : en
Publisher:
Release Date : 2014
Patient Derived Xenografts As Pre Clinical Models Of Response To Chemotherapy written by Paulina Cybulska and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
Modeling Human Cancer Therapy Response In Patient Derived Xenografts
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Author : Joan Malcolm
language : en
Publisher:
Release Date : 2018
Modeling Human Cancer Therapy Response In Patient Derived Xenografts written by Joan Malcolm and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Cancer categories.
Establishment Of Patient Derived Xenografts Pdxs From Metastatic Nasopharyngeal Carcinoma
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Author : 游嬋平
language : en
Publisher:
Release Date : 2021
Establishment Of Patient Derived Xenografts Pdxs From Metastatic Nasopharyngeal Carcinoma written by 游嬋平 and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Nasopharynx categories.
Translational Research In Breast Cancer
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Author : Dong-Young Noh
language : en
Publisher: Springer Nature
Release Date : 2021-05-13
Translational Research In Breast Cancer written by Dong-Young Noh and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-13 with Medical categories.
This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
Patient Derived Tumor Models For Drug Development
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Author : Hatim E. Sabaawy
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-31
Patient Derived Tumor Models For Drug Development written by Hatim E. Sabaawy and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-31 with Medical categories.