Pediatric Lymphomas
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Pediatric Lymphomas
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Author : Howard J. Weinstein
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-20
Pediatric Lymphomas written by Howard J. Weinstein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-20 with Medical categories.
This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.
Cancer Genomics
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Author : Nathanael G. Bailey
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-21
Cancer Genomics written by Nathanael G. Bailey and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.
Lymphomas account for approximately 10% of childhood malignancies. Pediatric lymphomas are typically aggressive: lymphoblastic lymphoma, Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL), and anaplastic large cell lymphoma (ALCL) are among the most common pediatric lymphoma subtypes. The genetic basis of these neoplasms is beginning to be understood. Lymphoblastic lymphomas arise through a variety of genetic pathways, dependent upon B- or T-progenitor origin. Aggressive B-cell lymphomas (BL and DLBCL) commonly arise secondary to errors that occur during physiologic B-cell development. BL is characterized by MYC translocation with an immunoglobulin locus enhancer. This lesion may also be present in DLBCL, particularly in children, but DLBCLs often have mutations of a variety of other genes, such as BCL6. DLBCL may be separated into germinal center B-cell-like (GCB) and activated B-cell-like groups. Pediatric DLBCL are more commonly in the GCB category than are adult DLBCL. Adult DLBCL has a tendency toward increased genomic complexity compared with pediatric DLBCL. ALCL is a T-cell lymphoma that is typically characterized by ALK fusions, most commonly with NPM. Genomic profiling has identified areas of recurrent genetic gains and losses in ALCL. Understanding the underlying genetic basis of lymphoma provides hope for the development of more targeted therapies for this group of diseases. However, further investigation of the lymphoma genome is necessary, particularly in pediatric patients.
Non Hodgkin S Lymphoma In Childhood And Adolescence
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Author : Oussama Abla
language : en
Publisher: Springer
Release Date : 2019-04-09
Non Hodgkin S Lymphoma In Childhood And Adolescence written by Oussama Abla and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-09 with Medical categories.
This text provides a state-of-the-art overview on Non-Hodgkin's lymphoma (NHL) in children and adolescents. The volume is divided into seven sections, each of which focuses on a critical component of pediatric NHL, including history and epidemiology, pathology and molecular biology, disease evaluation and response, common and rare sub-types of NHL, and current and novel treatment strategies. The text also comprehensively reviews the late effects of treatment, quality of patient life, and NHL treatment in countries with limited resources. Written by experts in the field, Non-Hodgkin's Lymphoma in Childhood and Adolescence is a valuable resource for clinicians and practitioners who treat children and adolescents with NHL.
Non Hodgkin S Lymphomas In Children
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Author : John Graham-Pole
language : en
Publisher:
Release Date : 1980
Non Hodgkin S Lymphomas In Children written by John Graham-Pole and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.
Hematological Malignancies In Children Adolescents And Young Adults
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Author : Mitchell S. Cairo
language : en
Publisher: World Scientific
Release Date : 2012
Hematological Malignancies In Children Adolescents And Young Adults written by Mitchell S. Cairo and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Bringing together intellectual and scientific experts from pediatrics, adolescent medicine, general medicine, pathology, biology, nursing and psychology, this book is the first of its kind to cover the topics of leukemias and lymphomas in young patients ranging from infants to young adults. The content is organized and subdivided into four major sections -- under the main headings of General Considerations, Pathobiology, Clinical Manifestations and Treatment, and Supportive Care and Complications -- for ease of reference to readers. Hematological Malignancies in Children, Adolescents and Young Adults presents a comprehensive multidisciplinary review of the field of hematological malignancies and brings forth illuminating perspectives from an internationally recognized group of leading authorities in the field.
Cancer Incidence And Survival Among Children And Adolescents
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Author :
language : en
Publisher:
Release Date : 1999
Cancer Incidence And Survival Among Children And Adolescents written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Cancer categories.
Pediatric Hematopathology
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Author : Robert D. Collins (M.D.)
language : en
Publisher:
Release Date : 2001
Pediatric Hematopathology written by Robert D. Collins (M.D.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Blood categories.
Written by the most esteemed experts in the field, this is the only reference completely dedicated to this topic. It offers comprehensive coverage of the full spectrum of hematologic, lymphatic, and myeloid diseases in children, including both neoplastic and non-neoplastic disorders, exploring the most important clinical/pathologic childhood syndromes in depth. Over 500 full-color illustrations, "perils and pitfalls," as well as a logical anatomic organization makes this an accessible and essential resource!
Clinical Pediatric Oncology
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Author : Wataru Walter Sutow
language : en
Publisher:
Release Date : 1984
Clinical Pediatric Oncology written by Wataru Walter Sutow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Medical categories.
Pediatric Acute Lymphoblastic Leukemia
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Author : Motohiro Kato
language : en
Publisher: Springer Nature
Release Date : 2019-11-26
Pediatric Acute Lymphoblastic Leukemia written by Motohiro Kato and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with Medical categories.
This book discusses key aspects of childhood acute lymphoblastic leukemia (ALL), presenting the latest research on the biology and treatment of the disease and related issues. The cure rate for ALL has improved dramatically due to advances such as supportive care, treatment stratification based on relapse risk, and the optimization of treatment regimens. Gathering contributions by eminent scholars Pediatric Acute Lymphoblastic Leukemia is a valuable resource for pediatric hematologists as well as for medical students, interns, residents and fellows. It not only offers comprehensive insights, but also provides a springboard for future research.
Childhood Acute Lymphoblastic Leukemia
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Author : Ajay Vora
language : en
Publisher: Springer
Release Date : 2017-04-21
Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-21 with Medical categories.
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.