Pediatric Lymphomas
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Pediatric Lymphomas
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Author : Howard J. Weinstein
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-20
Pediatric Lymphomas written by Howard J. Weinstein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-20 with Medical categories.
This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.
Cancer Genomics
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Author : Nathanael G. Bailey
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-11-21
Cancer Genomics written by Nathanael G. Bailey and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-21 with Medical categories.
Lymphomas account for approximately 10% of childhood malignancies. Pediatric lymphomas are typically aggressive: lymphoblastic lymphoma, Burkitt lymphoma (BL), diffuse large B-cell lymphoma (DLBCL), and anaplastic large cell lymphoma (ALCL) are among the most common pediatric lymphoma subtypes. The genetic basis of these neoplasms is beginning to be understood. Lymphoblastic lymphomas arise through a variety of genetic pathways, dependent upon B- or T-progenitor origin. Aggressive B-cell lymphomas (BL and DLBCL) commonly arise secondary to errors that occur during physiologic B-cell development. BL is characterized by MYC translocation with an immunoglobulin locus enhancer. This lesion may also be present in DLBCL, particularly in children, but DLBCLs often have mutations of a variety of other genes, such as BCL6. DLBCL may be separated into germinal center B-cell-like (GCB) and activated B-cell-like groups. Pediatric DLBCL are more commonly in the GCB category than are adult DLBCL. Adult DLBCL has a tendency toward increased genomic complexity compared with pediatric DLBCL. ALCL is a T-cell lymphoma that is typically characterized by ALK fusions, most commonly with NPM. Genomic profiling has identified areas of recurrent genetic gains and losses in ALCL. Understanding the underlying genetic basis of lymphoma provides hope for the development of more targeted therapies for this group of diseases. However, further investigation of the lymphoma genome is necessary, particularly in pediatric patients.
Non Hodgkin S Lymphoma In Childhood And Adolescence
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Author : Oussama Abla
language : en
Publisher: Springer
Release Date : 2019-04-09
Non Hodgkin S Lymphoma In Childhood And Adolescence written by Oussama Abla and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-09 with Medical categories.
This text provides a state-of-the-art overview on Non-Hodgkin's lymphoma (NHL) in children and adolescents. The volume is divided into seven sections, each of which focuses on a critical component of pediatric NHL, including history and epidemiology, pathology and molecular biology, disease evaluation and response, common and rare sub-types of NHL, and current and novel treatment strategies. The text also comprehensively reviews the late effects of treatment, quality of patient life, and NHL treatment in countries with limited resources. Written by experts in the field, Non-Hodgkin's Lymphoma in Childhood and Adolescence is a valuable resource for clinicians and practitioners who treat children and adolescents with NHL.
Non Hodgkin S Lymphomas In Children
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Author : John Graham-Pole
language : en
Publisher:
Release Date : 1980
Non Hodgkin S Lymphomas In Children written by John Graham-Pole and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Medical categories.
Hematological Malignancies In Children Adolescents And Young Adults
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Author : Mitchell S. Cairo
language : en
Publisher: World Scientific
Release Date : 2012
Hematological Malignancies In Children Adolescents And Young Adults written by Mitchell S. Cairo and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Bringing together intellectual and scientific experts from pediatrics, adolescent medicine, general medicine, pathology, biology, nursing and psychology, this book is the first of its kind to cover the topics of leukemias and lymphomas in young patients ranging from infants to young adults. The content is organized and subdivided into four major sections -- under the main headings of General Considerations, Pathobiology, Clinical Manifestations and Treatment, and Supportive Care and Complications -- for ease of reference to readers. Hematological Malignancies in Children, Adolescents and Young Adults presents a comprehensive multidisciplinary review of the field of hematological malignancies and brings forth illuminating perspectives from an internationally recognized group of leading authorities in the field.
Cancer Incidence And Survival Among Children And Adolescents
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Author :
language : en
Publisher:
Release Date : 1999
Cancer Incidence And Survival Among Children And Adolescents written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Cancer categories.
Pediatric Oncology
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Author : Ka Wah Chan
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-30
Pediatric Oncology written by Ka Wah Chan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-30 with Medical categories.
Childhood cancer was almost always fatal before 1970. Today, 80% of ch- dren diagnosed with cancer will survive at least 5 years; 70% will be cured. However, cancer continues to be the leading cause of nonaccident-related deaths in children. More children die each year from cancer than from c- tic ?brosis, diabetes, asthma, AIDS, and congenital abnormalities combined. Nine children die from cancer every school day. Despite the fact that pediatric cancers account for only a small p- centage of the total cancer burden, more effective therapies are needed to improve mortality rates in children. Therefore, our research priority must be the development of new agents and new therapies for childhood cancer. M. D. Anderson Cancer Center has been caring for children with c- cer since its doors opened over 60 years ago. This institution has been home to several research and clinical pioneers whose innovative work has in?uenced and shaped the practice of pediatric oncology throughout the world. Notably, Drs. Wataru W. Sutow, Donald Pinkel, and Norman Jaffe have been credited with introducing curative therapies for children with leukemia and solid tumors. Cancer treatment involves far more than administering chemoth- apy and surgically excising tumors. It requires a multidisciplinary - proach to patient management, particularly in the treatment of solid - mors, which pose the biggest challenge in cancer care today. Surgery and radiotherapy as well as radiographic and pathologic assessments of response are critical factors in the treatment of children with cancer.
Pediatric Hematopathology
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Author : Robert D. Collins (M.D.)
language : en
Publisher:
Release Date : 2001
Pediatric Hematopathology written by Robert D. Collins (M.D.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Blood categories.
Written by the most esteemed experts in the field, this is the only reference completely dedicated to this topic. It offers comprehensive coverage of the full spectrum of hematologic, lymphatic, and myeloid diseases in children, including both neoplastic and non-neoplastic disorders, exploring the most important clinical/pathologic childhood syndromes in depth. Over 500 full-color illustrations, "perils and pitfalls," as well as a logical anatomic organization makes this an accessible and essential resource!
Oncology
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Author :
language : en
Publisher:
Release Date : 2009
Oncology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Hematopoietic Cell Transplantation In Children With Cancer
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Author : Franklin O. Smith
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-26
Hematopoietic Cell Transplantation In Children With Cancer written by Franklin O. Smith and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Medical categories.
This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.